Compile Data Set for Download or QSAR
Report error Found 130 of affinity data for UniProtKB/TrEMBL: Q5JUK3
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607089(CHEMBL5219661)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of wild-type human Slack expressed in HEK293 cells measured by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607090(CHEMBL5219508)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of wild-type human Slack expressed in HEK293 cells measured by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607091(CHEMBL5220385)
Affinity DataEC50:  4.60E+3nMAssay Description:Activation of wild-type human Slack expressed in HEK293 cells measured by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607092(CHEMBL5220710)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of wild-type human Slack expressed in HEK293 cells measured by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607093(CHEMBL5219707)
Affinity DataEC50:  7.60E+3nMAssay Description:Activation of wild-type human Slack expressed in HEK293 cells measured by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607094(CHEMBL5219059)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of wild-type human Slack expressed in HEK293 cells measured by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607095(CHEMBL5219384)
Affinity DataEC50:  4.10E+3nMAssay Description:Activation of wild-type human Slack expressed in HEK293 cells measured by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607096(CHEMBL5218718)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of wild-type human Slack expressed in HEK293 cells measured by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607097(CHEMBL5220290)
Affinity DataEC50:  3.80E+3nMAssay Description:Activation of wild-type human Slack expressed in HEK293 cells measured by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607098(CHEMBL5219750)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of wild-type human Slack expressed in HEK293 cells measured by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607099(CHEMBL5220142)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of wild-type human Slack expressed in HEK293 cells measured by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607100(CHEMBL5218865)
Affinity DataEC50:  9.00E+3nMAssay Description:Activation of wild-type human Slack expressed in HEK293 cells measured by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607101(CHEMBL5219578)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of wild-type human Slack expressed in HEK293 cells measured by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607102(CHEMBL5221109)
Affinity DataEC50:  9.30E+3nMAssay Description:Activation of wild-type human Slack expressed in HEK293 cells measured by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607103(CHEMBL5219977)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of wild-type human Slack expressed in HEK293 cells measured by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607104(CHEMBL5219883)
Affinity DataEC50:  1.00E+4nMAssay Description:Activation of wild-type human Slack expressed in HEK293 cells measured by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50593373(CHEMBL5182581)
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of SLACK channel (unknown origin) by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50557676(CHEMBL4763955)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50557672(CHEMBL4788669)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50557680(CHEMBL4741793)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50557680(CHEMBL4741793)
Affinity DataIC50: 40nMAssay Description:Inhibition of wild-type human Slack expressed in HEK293 cells measured by automated patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50557678(CHEMBL4754084)
Affinity DataIC50: 61nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50557660(CHEMBL4783741)
Affinity DataIC50: 136nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50557666(CHEMBL4786255)
Affinity DataIC50: 165nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50557652(CHEMBL4793291)
Affinity DataIC50: 167nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50557679(CHEMBL4793279)
Affinity DataIC50: 195nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50557677(CHEMBL4750925)
Affinity DataIC50: 322nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50557656(CHEMBL4783466)
Affinity DataIC50: 335nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50557674(CHEMBL4795194)
Affinity DataIC50: 454nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50557675(CHEMBL4743249)
Affinity DataIC50: 505nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50557673(CHEMBL4781553)
Affinity DataIC50: 573nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50557682(CHEMBL4745211)
Affinity DataIC50: 744nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50557683(CHEMBL4758890)
Affinity DataIC50: 778nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50557659(CHEMBL4779088)
Affinity DataIC50: 977nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM617412(US20230285377, Example 1)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM617413(US20230285377, Example 2)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM617415(US20230285377, Example 4)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM617416(US20230285377, Example 5)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM617418(US20230285377, Example 6)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM617419(US20230285377, Example 7)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM617422(US20230285377, Example 10)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM617423(US20230285377, Example 11)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM617424(US20230285377, Example 12)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM617425(US20230285377, Example 13)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM617426(US20230285377, Example 14)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM617428(US20230285377, Example 16)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM617431(US20230285377, Example 19)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM617434(US20230285377, Example 21)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM617439(US20230285377, Example 25)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

TargetPotassium channel subfamily T member 1(Human)
University of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM617447(US20230285377, Example 31)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

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