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TargetDNA gyrase subunit A(Escherichia coli)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50521804(CHEMBL4581035)
Affinity DataIC50: 19nMAssay Description:Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50521806(CHEMBL4449908)
Affinity DataIC50: 37nMAssay Description:Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50521803(CHEMBL4568624)
Affinity DataIC50: 82nMAssay Description:Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50521799(CHEMBL4459270)
Affinity DataIC50: 86nMAssay Description:Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50521800(CHEMBL4470688)
Affinity DataIC50: 89nMAssay Description:Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50521805(CHEMBL4436644)
Affinity DataIC50: 120nMAssay Description:Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50521801(CHEMBL4521306)
Affinity DataIC50: 150nMAssay Description:Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50521802(CHEMBL4465300)
Affinity DataIC50: 200nMAssay Description:Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 280nMAssay Description:Inhibition of Escherichia coli DNA gyrase (A2B2 tetramer) using relaxed pBR322 as substrate preincubated for 30 mins followed by enzyme addition by S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50521807(CHEMBL4577939)
Affinity DataIC50: 410nMAssay Description:Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50045004(9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-ox...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Escherichia coli DNA gyrase GyrA/GyrBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50366824(Avelox | MOXIFLOXACIN | Moxifl-oxacin)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Escherichia coli DNA gyrase GyrA/GyrBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Escherichia coli)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM50296358(enofloxacin | 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of Escherichia coli DNA gyrase GyrA/GyrBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM21691(1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridi...)
Affinity DataIC50: 2.15E+5nMAssay Description:Inhibition of Escherichia coli DNA gyrase GyrA/GyrBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed