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TargetSerine/threonine-protein kinase ATR(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  4.47E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50341209(9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phen...)
Affinity DataEC50:  35nMAssay Description:Inhibition of ATR in human HCT116 cells assessed as after 1 hr by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  11nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50043407(CHEMBL3355476)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human ATR using ATP substrate measured after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM412060(US10392391, Compound I-G-32 | 2-amino-6-fluoro-N-[...)
Affinity DataIC50: 0.150nMMore data for this Ligand-Target Pair
Ligand InfoPurchaseSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM350086(US10208027, Compound II-2 | 3-[3-[4-[dideuterio-(t...)
Affinity DataIC50: 0.170nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50043409(CHEMBL3355474)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human ATR using ATP substrate measured after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM411480(US10392376, Example 40b | US10392376, Example 40a ...)
Affinity DataIC50: 0.300nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/20/2020
Entry Details
Go to US Patent

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM411480(US10392376, Example 40b | US10392376, Example 40a ...)
Affinity DataIC50: 0.300nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM411480(US10392376, Example 40b | US10392376, Example 40a ...)
Affinity DataIC50: 0.300nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
11/13/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase ATR(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50043385(CHEMBL3355072)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of ATR (unknown origin) using Avi-tagged protein substrate by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM724380(US20250066350, Example RP3500)
Affinity DataIC50: 0.330nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM411490(US10392376, Example 44b | US10392376, Example 44a ...)
Affinity DataIC50: 0.400nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/20/2020
Entry Details
Go to US Patent

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM411535(US10392376, Example 86 | (R)-((2-(2-(difluoro- met...)
Affinity DataIC50: 0.400nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/20/2020
Entry Details
Go to US Patent

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM411490(US10392376, Example 44b | US10392376, Example 44a ...)
Affinity DataIC50: 0.400nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM411535(US10392376, Example 86 | (R)-((2-(2-(difluoro- met...)
Affinity DataIC50: 0.400nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase ATR(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50043387(CHEMBL3355074)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of ATR (unknown origin) using Avi-tagged protein substrate by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50043408(CHEMBL3355475 | US20250051362, Comparative Compoun...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human ATR using ATP substrate measured after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM570458(US11434233, Example 44b)
Affinity DataIC50: 0.400nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2022
Entry Details
Go to US Patent

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM411535(US10392376, Example 86 | (R)-((2-(2-(difluoro- met...)
Affinity DataIC50: 0.400nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
11/13/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase ATR(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM714736(US20250026742, Example 35-1)
Affinity DataIC50: 0.410nMAssay Description:Prepare various buffer systems required for the experiment:1. Prepare ATR reaction buffer containing 25 mM HEPES (Gibco, Cat #15630-080), 5 mM DTT (S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
Go to US Patent

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM411502(US10392376, Example 53 | US10800769, Example 53 | ...)
Affinity DataIC50: 0.5nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2020
Entry Details
Go to US Patent

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM411502(US10392376, Example 53 | US10800769, Example 53 | ...)
Affinity DataIC50: 0.5nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase ATR(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50043382(CHEMBL3355069)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of ATR (unknown origin) using Avi-tagged protein substrate by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50043384(CHEMBL3355071)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of ATR (unknown origin) using Avi-tagged protein substrate by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50043411(CHEMBL3355480)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human ATR using ATP substrate measured after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM411502(US10392376, Example 53 | US10800769, Example 53 | ...)
Affinity DataIC50: 0.5nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase ATR [14-953](Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM647614(US20240025899, Compound 3 | (R)-N,N-dimethyl-4-(3-...)
Affinity DataIC50: 0.510nMAssay Description:In this experiment, the phosphorylation level of substrate protein P53 (Eurofins, 14-952) was detected by HTRF technology to measure the activity of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase ATR(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM714737(5-(5-amino-6-(5-(4-((1-methylpiperidin-4-yl)amino)...)
Affinity DataIC50: 0.570nMAssay Description:Prepare various buffer systems required for the experiment:1. Prepare ATR reaction buffer containing 25 mM HEPES (Gibco, Cat #15630-080), 5 mM DTT (S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase ATR(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM268079(2-[(3R)-3-methylmorpholin-4-yl]-4-(1-methyl-1H-pyr...)
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR [14-953](Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM647613(US20240025899, Compound 2 | (R)-3-methyl-4-(1-(met...)
Affinity DataIC50: 0.690nMAssay Description:In this experiment, the phosphorylation level of substrate protein P53 (Eurofins, 14-952) was detected by HTRF technology to measure the activity of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM411476(US10392376, Example 38b | US10392376, Example 38a ...)
Affinity DataIC50: 0.700nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/20/2020
Entry Details
Go to US Patent

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM411476(US10392376, Example 38b | US10392376, Example 38a ...)
Affinity DataIC50: 0.700nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM411476(US10392376, Example 38b | US10392376, Example 38a ...)
Affinity DataIC50: 0.700nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
11/13/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase ATR(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM714724(1-(4-(5-(3-amino-6-(4-(cyclopropylsulfonyl)phenyl)...)
Affinity DataIC50: 0.700nMAssay Description:Prepare various buffer systems required for the experiment:1. Prepare ATR reaction buffer containing 25 mM HEPES (Gibco, Cat #15630-080), 5 mM DTT (S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase ATR(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM714739(US20250026742, Example 38-1)
Affinity DataIC50: 0.75nMAssay Description:Prepare various buffer systems required for the experiment:1. Prepare ATR reaction buffer containing 25 mM HEPES (Gibco, Cat #15630-080), 5 mM DTT (S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase ATR(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM714728(1-(4-(5-(3-amino)-6-(1,1-dioxo-2,3-dihydrobenzo[b]...)
Affinity DataIC50: 0.75nMAssay Description:Prepare various buffer systems required for the experiment:1. Prepare ATR reaction buffer containing 25 mM HEPES (Gibco, Cat #15630-080), 5 mM DTT (S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase ATR(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM714738(5-(5-amino-6-(5-(4-((methylamino)methyl)phenyl)-1,...)
Affinity DataIC50: 0.770nMAssay Description:Prepare various buffer systems required for the experiment:1. Prepare ATR reaction buffer containing 25 mM HEPES (Gibco, Cat #15630-080), 5 mM DTT (S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
Go to US Patent

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM411480(US10392376, Example 40b | US10392376, Example 40a ...)
Affinity DataIC50: 0.800nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/20/2020
Entry Details
Go to US Patent

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM411482(US10392376, Example 41b | US10392376, Example 41a ...)
Affinity DataIC50: 0.800nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/20/2020
Entry Details
Go to US Patent

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM411480(US10392376, Example 40b | US10392376, Example 40a ...)
Affinity DataIC50: 0.800nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM411482(US10392376, Example 41b | US10392376, Example 41a ...)
Affinity DataIC50: 0.800nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase ATR(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM730138(US12264155, Compound 24)
Affinity DataIC50: 0.800nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM570452(US11434233, Example 41b)
Affinity DataIC50: 0.800nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2022
Entry Details
Go to US Patent

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM411480(US10392376, Example 40b | US10392376, Example 40a ...)
Affinity DataIC50: 0.800nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
11/13/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase ATR(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM714712(1-(4-(5-(3-amino-6-(4-(isopropylsulfonyl)phenyl)py...)
Affinity DataIC50: 0.820nMAssay Description:Prepare various buffer systems required for the experiment:1. Prepare ATR reaction buffer containing 25 mM HEPES (Gibco, Cat #15630-080), 5 mM DTT (S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase ATR(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM714705(1-(4-(5-(3-amino-6-(4-isopropylsulfonyl)phenyl)pyr...)
Affinity DataIC50: 0.830nMAssay Description:Prepare various buffer systems required for the experiment:1. Prepare ATR reaction buffer containing 25 mM HEPES (Gibco, Cat #15630-080), 5 mM DTT (S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase ATR(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM714734(US20250026742, Example 33-1)
Affinity DataIC50: 0.830nMAssay Description:Prepare various buffer systems required for the experiment:1. Prepare ATR reaction buffer containing 25 mM HEPES (Gibco, Cat #15630-080), 5 mM DTT (S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
Go to US Patent

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM411501(US10392376, Example 52 | US10800769, Example 52 | ...)
Affinity DataIC50: 0.900nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/20/2020
Entry Details
Go to US Patent

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM411544(US10392376, Example 95 | Cyclopropyl(methyl)((2- (...)
Affinity DataIC50: 0.900nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/20/2020
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