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Report error Found 31 for UniProtKB: Q13148
TargetTAR DNA-binding protein 43(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50544712(CHEMBL4635203)
Affinity DataIC50: 100nMAssay Description:Inhibition of TDP-43 (unknown origin) binding to RNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetTAR DNA-binding protein 43(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50544711(CHEMBL4647070)
Affinity DataIC50: 100nMAssay Description:Inhibition of TDP-43 (unknown origin) binding to RNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetTAR DNA-binding protein 43(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  176nMAssay Description:Binding affinity to human TARDBP incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM645392(US20240016810, Compound TABLE 16.5 | US20240208964...)
Affinity DataIC50: 230nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandPNGBDBM50590927(Apilimod | Sta-5326 | STA 5326 | STA-5326 | APILIM...)
Affinity DataIC50: 450nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandPNGBDBM645399(US20240016810, Compound TABLE 16.12 | US2024020896...)
Affinity DataIC50: 693nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetTAR DNA-binding protein 43(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  814nMAssay Description:Binding affinity to human TARDBP incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM645389(US20240016810, Compound TABLE 16.3 | US20240208964...)
Affinity DataIC50: 1.12E+3nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandPNGBDBM50590929(CHEMBL4303292 | US20240016810, Compound TABLE 16.2...)
Affinity DataIC50: 1.39E+3nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandPNGBDBM645402(US20240016810, Compound TABLE 16.15 | US2024020896...)
Affinity DataIC50: 1.45E+3nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandPNGBDBM645407(US20240016810, Compound TABLE 16.20 | US2024020896...)
Affinity DataIC50: 2.69E+3nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandPNGBDBM739550(US20250145642, Compound 45 | US20250197375, Compou...)
Affinity DataIC50: 4.27E+3nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandPNGBDBM645378(US20240016810, Compound TABLE 16.11 | US2024001681...)
Affinity DataIC50: 4.72E+3nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandPNGBDBM645410(US20240016810, Compound TABLE 16.23 | US2024020896...)
Affinity DataIC50: 5.75E+3nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandPNGBDBM645401(US20240016810, Compound TABLE 16.14 | US2024020896...)
Affinity DataIC50: 8.21E+3nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandPNGBDBM645400(US20240016810, Compound TABLE 16.13 | US2024020896...)
Affinity DataIC50: 9.11E+3nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetTAR DNA-binding protein 43(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM67690(SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TDP-43 (unknown origin) binding to RNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
LigandPNGBDBM645394(US20240016810, Compound TABLE 16.7 | US20240208964...)
Affinity DataIC50: 1.50E+4nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandPNGBDBM645393(US20240016810, Compound TABLE 16.6 | US20240208964...)
Affinity DataIC50: 1.50E+4nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandPNGBDBM645409(US20240016810, Compound TABLE 16.22 | US2024020896...)
Affinity DataIC50: 1.50E+4nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandPNGBDBM645408(US20240016810, Compound TABLE 16.21 | US2024020896...)
Affinity DataIC50: 1.50E+4nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandPNGBDBM645391(US20240016810, Compound TABLE 16.4 | US20240208964...)
Affinity DataIC50: 1.50E+4nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandPNGBDBM645380(US20240016810, Compound TABLE 16.10 | US2024001681...)
Affinity DataIC50: 1.50E+4nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandPNGBDBM645405(US20240016810, Compound TABLE 16.18 | US2024020896...)
Affinity DataIC50: 1.50E+4nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandPNGBDBM645396(US20240016810, Compound TABLE 16.9 | US20240208964...)
Affinity DataIC50: 1.50E+4nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandPNGBDBM645404(US20240016810, Compound TABLE 16.17 | US2024020896...)
Affinity DataIC50: 1.50E+4nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandPNGBDBM645395(US20240016810, Compound TABLE 16.8 | US20240208964...)
Affinity DataIC50: 1.50E+4nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandPNGBDBM645403(US20240016810, Compound TABLE 16.16 | US2024020896...)
Affinity DataIC50: 1.50E+4nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetTAR DNA-binding protein 43(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50106731((R)-(+)-lipoic acid | (R)-1,2-Dithiolane-3-pentano...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of TDP-43 (unknown origin) binding to RNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetTAR DNA-binding protein 43(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM16435(5-(1,2-dithiolan-3-yl)pentanamide | Thioctamide | ...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of TDP-43 (unknown origin) binding to RNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetTAR DNA-binding protein 43(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50544713(CHEMBL4638490)
Affinity DataKd:  8.90E+4nMAssay Description:Binding affinity to TDP-43 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed