Compile Data Set for Download or QSAR
Report error Found 50 of affinity data for UniProtKB/TrEMBL: Q13003
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50178136((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl)...)
Affinity DataIC50: 4.00E+3nMAssay Description:Antagonist activity at recombinant GluK3 receptor (unknown origin) expressed in Xenopus oocyte assessed as inhibition of glutamate-induced current am...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50207594(2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(f)quinoxali...)
Affinity DataIC50: 4.40E+4nMAssay Description:Displacement of [3H]kainate from human GLUK7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50364074(CHEMBL1950805)
Affinity DataIC50: 8.13E+4nMAssay Description:Antagonist activity at human recombinant GluK3 receptor expressed in human HEK293 cells assessed as inhibition of glutamate-stimulated calcium influx...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50185318((S)-3-((3-(2-amino-2-carboxyethyl)-2,6-dioxo-2,3-d...)
Affinity DataIC50: 2.64E+5nMAssay Description:Displacement of [3H]kainate from human GLUK7 expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50178148((RS)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl...)
Affinity DataIC50: 8.80E+5nMAssay Description:Displacement of [3H]kainate from human GLUK7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50646139(DOMOIC ACID)
Affinity DataKi:  4.80nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50002369(Digensaeure | (3S,4R)-3-(carboxymethyl)-4-(prop-1-...)
Affinity DataKi:  10nMAssay Description:Ability to bind to Ionotropic glutamate receptor ionotropic kainate 3 was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50002369(Digensaeure | (3S,4R)-3-(carboxymethyl)-4-(prop-1-...)
Affinity DataKi:  10nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 3 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50088216(LY-339296 | E-2-Amino-4-[3-(2-methoxy-phenyl)-ally...)
Affinity DataKi:  42nMAssay Description:Compound was tested for binding affinity against human Ionotropic glutamate receptor ionotropic kainate 3 in HEK293 cells using [3H]kainate as radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50116040((7-{3-[3-(4-Nitro-phenyl)-ureidomethyl]-pyrrol-1-y...)
Affinity DataKi:  46nMAssay Description:Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50591738(CHEMBL5193862)
Affinity DataKi:  142nMAssay Description:Binding affinity to GluK3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50088197(E-2-Amino-4-[3-(4-chloro-phenyl)-allyl]-pentanedio...)
Affinity DataKi:  423nMAssay Description:Ability to bind to Ionotropic glutamate receptor ionotropic kainate 3 was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50091474(LY-339637 | (2S,4E)-2-amino-4-(2-methylpropylidene...)
Affinity DataKi:  518nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 3 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50116044({6-Nitro-2,3-dioxo-7-[3-(4-phenyl-piperidin-1-ylme...)
Affinity DataKi:  530nMAssay Description:Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50088222(LY-339434 | (2S,4R)-2-Amino-4-((E)-3-naphthalen-2-...)
Affinity DataKi:  617nMAssay Description:Ability to bind to Ionotropic glutamate receptor ionotropic kainate 3 was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50088222(LY-339434 | (2S,4R)-2-Amino-4-((E)-3-naphthalen-2-...)
Affinity DataKi:  617nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 3 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50116042({7-[3-(4-Benzyl-piperazin-1-ylmethyl)-pyrrol-1-yl]...)
Affinity DataKi:  680nMAssay Description:Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM17657(L-Glutamic acid | L-Glu | (2S)-2-aminopentanedioic...)
Affinity DataKi:  789nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 3 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | D-Glu | D-Glutamat...)
Affinity DataKi:  789nMAssay Description:Ability to bind to Ionotropic glutamate receptor ionotropic kainate 3 was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50591736(CHEMBL5173718)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity to GluK3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50591735(CHEMBL5209119)
Affinity DataKi:  1.19E+3nMAssay Description:Binding affinity to GluK3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50116048({6-Nitro-2,3-dioxo-7-[3-(4-phenethyl-piperazin-1-y...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50116047((6-Nitro-2,3-dioxo-7-{3-[(3-phenyl-propylamino)-me...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50116043(3-(6-Nitro-2,3-dioxo-7-pyrrol-1-yl-3,4-dihydro-2H-...)
Affinity DataKi:  2.50E+3nMAssay Description:Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50591737(CHEMBL5206048)
Affinity DataKi:  2.91E+3nMAssay Description:Binding affinity to GluK3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50116050(1-(4-Carboxymethyl-7-nitro-2,3-dioxo-1,2,3,4-tetra...)
Affinity DataKi:  4.10E+3nMAssay Description:Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50116041([6-Nitro-2,3-dioxo-7-(3-piperidin-1-ylmethyl-pyrro...)
Affinity DataKi:  5.70E+3nMAssay Description:Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50091477((S)-2-Amino-4-cyclopentylidene-pentanedioic acid |...)
Affinity DataKi:  5.73E+3nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 3 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50591734(CHEMBL5208673)
Affinity DataKi:  6.60E+3nMAssay Description:Binding affinity to GluK3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50200526(CHEMBL1234118)
Affinity DataKi:  8.90E+3nMAssay Description:Inhibition of GluK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2019
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM86754(LY-466195 | LY 466195)
Affinity DataKi:  8.90E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50591739(CHEMBL5186117)
Affinity DataKi:  8.90E+3nMAssay Description:Binding affinity to GluK3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50168962(LY 382884 | CHEMBL274226 | 6-(4-Carboxy-benzyl)-de...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM86751(CHEMBL14935 | LY-293558 | LY 293558)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50091475((2S,4Z)-2-amino-4-(2-methylpropylidene)pentanedioi...)
Affinity DataKi:  1.05E+4nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 3 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50091473(LY-339687 | (S)-2-Amino-4-(1-ethyl-propylidene)-pe...)
Affinity DataKi:  1.24E+4nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 3 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50207594(2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(f)quinoxali...)
Affinity DataKi:  1.80E+4nMAssay Description:Displacement of [3H]kainate from human GLUK7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50591732(CHEMBL5198336)
Affinity DataKi:  3.70E+4nMAssay Description:Binding affinity to GluK3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50591730(CHEMBL5177751)
Affinity DataKi:  5.90E+4nMAssay Description:Binding affinity to GluK3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50591743(CHEMBL1375097)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to GluK3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM86751(CHEMBL14935 | LY-293558 | LY 293558)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to GluR7More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50591733(CHEMBL5190991)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to GluK3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50591731(CHEMBL5174264)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to GluK3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50591744(CHEMBL5195778)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to GluK3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50591742(CHEMBL5199355)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to GluK3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50591741(CHEMBL5187440)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to GluK3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50591740(CHEMBL5179605)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to GluK3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50591729(CHEMBL5188085)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to GluK3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50185318((S)-3-((3-(2-amino-2-carboxyethyl)-2,6-dioxo-2,3-d...)
Affinity DataKi:  1.11E+5nMAssay Description:Displacement of [3H]kainate from human GLUK7 expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50178148((RS)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl...)
Affinity DataKi:  3.74E+5nMAssay Description:Displacement of [3H]kainate from human GLUK7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed