Compile Data Set for Download or QSAR
Report error Found 35 of affinity data for UniProtKB/TrEMBL: Q05921
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50189862({[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-[({[(2...)
Affinity DataEC50:  3.60nMAssay Description:Activation of mouse RNase L assessed as ability to cleave 5'-[32P]r(C11U2C7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50189858({[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-[({[(2...)
Affinity DataEC50:  393nMAssay Description:Activation of mouse RNase L assessed as ability to cleave 5'-[32P]r(C11U2C7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50189859({[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-[({[(2...)
Affinity DataEC50:  0.900nMAssay Description:Activation of mouse RNase L assessed as ability to cleave 5'-[32P]r(C11U2C7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50189860({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-[({[(2...)
Affinity DataEC50:  323nMAssay Description:Activation of mouse RNase L assessed as ability to cleave 5'-[32P]r(C11U2C7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50189861({[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-[({[(2...)
Affinity DataEC50:  1.30nMAssay Description:Activation of mouse RNase L assessed as ability to cleave 5'-[32P]r(C11U2C7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50189863({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-[({[(2...)
Affinity DataEC50:  396nMAssay Description:Activation of mouse RNase L assessed as ability to cleave 5'-[32P]r(C11U2C7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50421415(CHEMBL414948)
Affinity DataIC50: 0.950nMAssay Description:Inhibitory activity to prevent binding of added ppp5'A2'p5'A2'pA2'p5'A3'[32P]p5' (c3 label) to RNase L in mouse L cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50370220(CHEMBL1163094)
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]-labeled 2-5A from 2-5A dependent Ribonuclease L (RNase L) of mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50370219(CHEMBL610868)
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]-labeled 2-5A from 2-5A dependent Ribonuclease L (RNase L) of mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50025002(ppp5'A2'p5'A2'p5'A | ppp'A2'p5'A2'p5'A | CHEMBL404...)
Affinity DataIC50: 2.30nMAssay Description:Compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50373177(CHEMBL404038)
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]-labeled 2-5A from 2-5A dependent Ribonuclease L (RNase L) of mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50421415(CHEMBL414948)
Affinity DataIC50: 4nMAssay Description:Displacement of [125I]-labeled 2-5A from 2-5A dependent Ribonuclease L (RNase L) of mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50025005(pp5'(br8A)2'p5'(br8A)2'p5'(br8A) | CHEMBL3143469)
Affinity DataIC50: 48nMAssay Description:Compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50366437(CHEMBL608874)
Affinity DataIC50: 50nMAssay Description:Compound concentration which displaces 50% of [125I]-labeled 2-5A probe bound to RNase L from mouse L cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50370222(CHEMBL610866)
Affinity DataIC50: 50nMAssay Description:Displacement of [125I]-labeled 2-5A from 2-5A dependent Ribonuclease L (RNase L) of mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50370227(CHEMBL610609)
Affinity DataIC50: 70nMAssay Description:Displacement of [125I]-labeled 2-5A from 2-5A dependent Ribonuclease L (RNase L) of mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50025001(pp5'(br8A)2'p5'(br8A)2'p5'(br8A)2'p5'(br8A)2'p5'(b...)
Affinity DataIC50: 150nMAssay Description:Compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50025000(ppp5'(br8A)2'p5'(br8A)2'p5'(br8A) | CHEMBL3143409)
Affinity DataIC50: 250nMAssay Description:Compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50021104((2'-5'(pAris)3)
Affinity DataIC50: 320nMAssay Description:Inhibitory activity to prevent binding of added ppp5'A2'p5'A2'pA2'p5'A3'[32P]p5' (c3 label) to RNase L in mouse L cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50370221(CHEMBL610855)
Affinity DataIC50: 500nMAssay Description:Displacement of [125I]-labeled 2-5A from 2-5A dependent Ribonuclease L (RNase L) of mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50024997(p5'(br8A)2'p5'(br8A)2'p5'(br8A) | CHEMBL3143462)
Affinity DataIC50: 700nMAssay Description:Compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50025003((br8A)2'p5'(br8A)2'p5'(br8A) | CHEMBL3143413)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50370224(CHEMBL610867)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]-labeled 2-5A from 2-5A dependent Ribonuclease L (RNase L) of mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50370229(CHEMBL607600)
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of [125I]-labeled 2-5A from 2-5A dependent Ribonuclease L (RNase L) of mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50025006((br8A)2'p5'(br8A)2'p5'(br8A)2'p5'(br8A) | CHEMBL31...)
Affinity DataIC50: 4.00E+4nMAssay Description:Compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50366438(CHEMBL608875)
Affinity DataIC50: 4.00E+4nMAssay Description:Compound concentration which displaces 50% of [125I]-labeled 2-5A probe bound to RNase L from mouse L cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50366436(CHEMBL605454)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound concentration which displaces 50% of [125I]-labeled 2-5A probe bound to RNase L from mouse L cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50025004(p5'(br8A)2'p5'(br8A)2'p5'(br8A)2'p5'(br8A)2'p5'(br...)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50370226(CHEMBL607595)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [125I]-labeled 2-5A from 2-5A dependent Ribonuclease L (RNase L) of mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50370225(CHEMBL608161)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [125I]-labeled 2-5A from 2-5A dependent Ribonuclease L (RNase L) of mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50370228(CHEMBL607882)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [125I]-labeled 2-5A from 2-5A dependent Ribonuclease L (RNase L) of mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50370223(CHEMBL607888)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [125I]-labeled 2-5A from 2-5A dependent Ribonuclease L (RNase L) of mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50370230(CHEMBL610610)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [125I]-labeled 2-5A from 2-5A dependent Ribonuclease L (RNase L) of mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50024999(Sulfuric acid mono-{5-(6-amino-purin-9-yl)-4-[(5-(...)
Affinity DataIC50: 2.00E+5nMAssay Description:Compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50024998(p5'(br8A)2'p5'(br8A)2'p5'(br8A)2'p5'(br8A) | CHEMB...)
Affinity DataIC50: 2.00E+5nMAssay Description:Compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed