Compile Data Set for Download or QSAR
Report error Found 332 for UniProtKB: Q04631
LigandPNGBDBM50082910((S)-2-({5-[((S)-1-Cyclohexylmethyl-2-ethanesulfony...)
Affinity DataIC50: 0.140nMAssay Description:In vitro inhibitory activity against Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50082897((S)-2-({5-[((S)-2-Cyclohexyl-1-hydroxymethyl-ethyl...)
Affinity DataIC50: 0.160nMAssay Description:In vitro inhibitory activity against Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50082909(2-[(5-{[tert-Butoxycarbonyl-(2-cyclohexyl-ethyl)-a...)
Affinity DataIC50: 0.170nMAssay Description:In vitro inhibitory activity against Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50082918(2-({5-[(2-Cyclohexyl-ethylamino)-methyl]-2'-methyl...)
Affinity DataIC50: 0.170nMAssay Description:In vitro inhibitory activity against Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50082904((S)-2-({5-[((S)-1-Cyclohexylmethyl-2-phenylsulfany...)
Affinity DataIC50: 0.200nMAssay Description:In vitro inhibitory activity against Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM16180((2S)-2-{[4-({[(2S)-1-cyclohexyl-3-(ethylsulfanyl)p...)
Affinity DataIC50: 0.200nMAssay Description:In vitro inhibitory activity against Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50082895(2-({5-[(1-Cyclohexylmethyl-5-methyl-hex-2-enylamin...)
Affinity DataIC50: 0.220nMAssay Description:In vitro inhibitory activity against Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50082914(2-({5-[(2-Cyclohexyl-1-cyclohexylmethyl-ethylamino...)
Affinity DataIC50: 0.25nMAssay Description:In vitro inhibitory activity against Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50082899(2-({5-[(1-Cyclohexylmethyl-5-methyl-hex-2-enylamin...)
Affinity DataIC50: 0.280nMAssay Description:In vitro inhibitory activity against Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50082919((S)-2-({5-[((S)-1-Cyclohexylmethyl-2-cyclohexylsul...)
Affinity DataIC50: 0.410nMAssay Description:In vitro inhibitory activity against Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50082915((S)-2-({5-[((S)-1-Cyclohexylmethyl-2-o-tolylsulfan...)
Affinity DataIC50: 0.420nMAssay Description:In vitro inhibitory activity against Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50082907(2-({5-[(1-Cyclohexylmethyl-pentylamino)-methyl]-2'...)
Affinity DataIC50: 0.460nMAssay Description:In vitro inhibitory activity against Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50082905((S)-2-({5-[((S)-2-tert-Butylsulfanyl-1-cyclohexylm...)
Affinity DataIC50: 0.600nMAssay Description:In vitro inhibitory activity against Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50082911(2-({5-[(2-Cyclohexyl-1-methoxymethyl-ethylamino)-m...)
Affinity DataIC50: 0.660nMAssay Description:In vitro inhibitory activity against Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM13320(CHEMBL181102 | N-{6-cyano-1-[(1-methyl-1H-imidazol...)
Affinity DataIC50: 0.700nMAssay Description:Assays for PFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). IC50 values were cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2007
Entry Details Article
PubMed
LigandPNGBDBM50082901(2-({5-[(2-Cyclohexyl-1-methyl-ethylamino)-methyl]-...)
Affinity DataIC50: 0.700nMAssay Description:In vitro inhibitory activity against Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50082896(2-({5-[(1-Cyclohexylmethyl-propylamino)-methyl]-2'...)
Affinity DataIC50: 0.700nMAssay Description:In vitro inhibitory activity against Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50048399((S)-2-[((S)-2-{(S)-2-[2-(3H-Imidazol-4-yl)-ethylam...)
Affinity DataIC50: 0.790nMAssay Description:Activity against rat FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
LigandPNGBDBM50059856(2-(2-{(S)-3-[((S)-2-Amino-3-mercapto-propionyl)-me...)
Affinity DataIC50: 0.790nMAssay Description:Activity against rat FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
LigandPNGBDBM13321(N-(2-bromoprop-2-en-1-yl)-N-{6-cyano-1-[(1-methyl-...)
Affinity DataIC50: 0.800nMAssay Description:Assays for PFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). IC50 values were cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2007
Entry Details Article
PubMed
LigandPNGBDBM50059861(2-(2-{(S)-3-[((S)-2-Amino-3-mercapto-propionyl)-me...)
Affinity DataIC50: 0.850nMAssay Description:Activity against rat FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
LigandPNGBDBM50082913(2-[(5-{[(2-Cyclohexyl-ethyl)-methyl-amino]-methyl}...)
Affinity DataIC50: 0.870nMAssay Description:In vitro inhibitory activity against Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50082898((S)-2-({5-[((S)-2-Cyclohexyl-1-ethylsulfanylmethyl...)
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory activity against Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50082903(2-[(5-{[Benzoyl-(2-cyclohexyl-ethyl)-amino]-methyl...)
Affinity DataIC50: 1.10nMAssay Description:In vitro inhibitory activity against Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM13319(tetrahydroquinoline (THQ)-based inhibitor 4a | ter...)
Affinity DataIC50: 1.20nMAssay Description:Assays for PFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). IC50 values were cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2007
Entry Details Article
PubMed
LigandPNGBDBM13323(N-benzyl-N-{6-cyano-1-[(1-methyl-1H-imidazol-5-yl)...)
Affinity DataIC50: 1.20nMAssay Description:Assays for PFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). IC50 values were cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2007
Entry Details Article
PubMed
LigandPNGBDBM50082894((S)-2-({5-[((S)-1-Cyclohexylmethyl-2-ethanesulfony...)
Affinity DataIC50: 1.20nMAssay Description:In vitro inhibitory activity against Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM13322(N-tert-butyl-2-({6-cyano-1-[(1-methyl-1H-imidazol-...)
Affinity DataIC50: 1.5nMAssay Description:Assays for PFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). IC50 values were cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2007
Entry Details Article
PubMed
LigandPNGBDBM13331(N-tert-butyl-2-({6-isocyano-1-[(1-methyl-1H-imidaz...)
Affinity DataIC50: 1.80nMAssay Description:Assays for PFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). IC50 values were cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2007
Entry Details Article
PubMed
LigandPNGBDBM14459((+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of rat brain FTase assessed as decrease in transfer of [3H]farnesyl from [3H]farnesyl PPi to H-Ras-CVLS after 30 mins by liquid scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50060140([(S)-1-{(4-Benzyloxy-benzyl)-[(2-cyano-2-phenyl-et...)
Affinity DataIC50: 2nMAssay Description:In vitro inhibition of rat farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50284631(2-(2-{3-[(2-Amino-3-mercapto-propionyl)-methyl-ami...)
Affinity DataIC50: 2.10nMAssay Description:Tested for inhibitory activity against rat brain p21ras Ras Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50059864((S)-2-({(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propy...)
Affinity DataIC50: 2.80nMAssay Description:Activity against rat FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
LigandPNGBDBM50082906(2-[(5-{[Acetyl-(2-cyclohexyl-ethyl)-amino]-methyl}...)
Affinity DataIC50: 2.90nMAssay Description:In vitro inhibitory activity against Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM13328(N-{6-cyano-1-[(1-methyl-1H-imidazol-5-yl)methyl]-1...)
Affinity DataIC50: 3nMAssay Description:Assays for PFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). IC50 values were cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2007
Entry Details Article
PubMed
LigandPNGBDBM50060144([(S)-1-{(4-Benzyloxy-benzyl)-[((R)-1-methyl-2-phen...)
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of rat farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM13325(tert-butyl 4-[({6-cyano-1-[(1-methyl-1H-imidazol-5...)
Affinity DataIC50: 3.20nMAssay Description:Assays for PFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). IC50 values were cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2007
Entry Details Article
PubMed
LigandPNGBDBM13324(N-{6-cyano-1-[(1-methyl-1H-imidazol-5-yl)methyl]-1...)
Affinity DataIC50: 3.40nMAssay Description:Assays for PFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). IC50 values were cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2007
Entry Details Article
PubMed
LigandPNGBDBM50082902(2-[(5-{[Benzyl-(2-cyclohexyl-ethyl)-amino]-methyl}...)
Affinity DataIC50: 3.5nMAssay Description:In vitro inhibitory activity against Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM13327(N-{6-cyano-1-[(1-methyl-1H-imidazol-5-yl)methyl]-1...)
Affinity DataIC50: 3.80nMAssay Description:Assays for PFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). IC50 values were cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2007
Entry Details Article
PubMed
LigandPNGBDBM50062250(trisodium 5-[2-benzo[d][1,3]dioxol-5-yl-5-benzo[d]...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of Farnesyltransferase from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50062251(trisodium 5-[2-benzo[d][1,3]dioxol-5-yl-5-benzo[d]...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of Farnesyltransferase from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50060141([(S)-1-{(4-Benzyloxy-benzyl)-[(2-methyl-2-phenyl-p...)
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of rat farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50082912((S)-2-({5-[((S)-1-Cyclohexyl-2-hydroxy-ethylamino)...)
Affinity DataIC50: 4nMAssay Description:In vitro inhibitory activity against Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055595([(R)-1-((R)-2-(4-Benzyloxy-phenyl)-1-{(S)-1-[(R)-1...)
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration against rat brain farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50082916((S)-2-({5-[((S)-1-Hydroxymethyl-2-phenyl-ethylamin...)
Affinity DataIC50: 4.60nMAssay Description:In vitro inhibitory activity against Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50100279(2-[3-(3-Ethyl-1-methyl-2-oxo-azepan-3-yl)-phenoxy]...)
Affinity DataIC50: 4.90nMAssay Description:Displacement of radiolabeled FTI from Farnesyltransferase in cultured v-Ha-ras-transformed RAT1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM13335(N-tert-butyl-2-({6-cyano-1-[(1-methyl-1H-imidazol-...)
Affinity DataIC50: 5nMAssay Description:Assays for PFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). IC50 values were cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2007
Entry Details Article
PubMed
LigandPNGBDBM50062249(trisodium 5-[2-benzo[d][1,3]dioxol-5-yl-5-benzo[d]...)
Affinity DataIC50: 5nMAssay Description:Inhibition of Farnesyltransferase from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50060145([(S)-1-{(4-Benzyloxy-benzyl)-[((S)-2-phenyl-propyl...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibition of rat farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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