Compile Data Set for Download or QSAR
Report error Found 558 for UniProtKB: Q02880
LigandPNGBDBM50213794(CHEMBL7690)
Affinity DataEC50:  360nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

LigandPNGBDBM50213296(CHEMBL267017)
Affinity DataEC50: >2.10E+5nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

LigandPNGBDBM50213808(CHEMBL7689)
Affinity DataEC50: >2.10E+5nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

LigandPNGBDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataEC50:  30nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286484(2-Cyclohexyl-5-cyclopropyl-7-(2,6-dimethyl-pyridin...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286474(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50: >6.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286486(5-Cyclopropyl-2-(2-dimethylamino-ethyl)-7-(2,6-dim...)
Affinity DataEC50:  930nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50127140(4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylid...)
Affinity DataEC50: >7.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article
PDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286489(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286490(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  2.70E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM87351(m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...)
Affinity DataEC50:  1.10E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article
PDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286492(2-(4-Amino-cyclohexyl)-5-cyclopropyl-7-(2,6-dimeth...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286491(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286496(2-(4-Amino-cyclohexyl)-5-cyclopropyl-7-(2,6-dimeth...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286488(5-Cyclopropyl-2-(4-dimethylamino-cyclohexyl)-7-(2,...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286497(N-{4-[5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-...)
Affinity DataEC50: >5.10E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50045698(WIN-57294 | 1-Cyclopropyl-7-(2,6-dimethyl-pyridin-...)
Affinity DataEC50: >5.40E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286495(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  1.20E+3nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286493([5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-d...)
Affinity DataEC50: >6.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286494(5-Cyclopropyl-2-(4-dimethylamino-cyclohexyl)-7-(2,...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286499(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50: >6.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286498(N-{4-[5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-...)
Affinity DataEC50: >5.20E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286501(5-Cyclopropyl-2-(3-dimethylamino-propyl)-7-(2,6-di...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286500(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50: >6.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286485(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286487([5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-d...)
Affinity DataEC50: >6.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50045706(1-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50: >5.50E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

LigandPNGBDBM50213994(CHEMBL280609)
Affinity DataEC50: >2.40E+5nMAssay Description:Inhibition of topoisomerase II purified from HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

LigandPNGBDBM50213995(CHEMBL25908)
Affinity DataEC50: >2.30E+5nMAssay Description:Inhibition of topoisomerase II purified from HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

LigandPNGBDBM50213996(CHEMBL30104)
Affinity DataEC50:  550nMAssay Description:Inhibition of topoisomerase II purified from HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

LigandPNGBDBM50213997(CHEMBL30099)
Affinity DataEC50: >2.20E+5nMAssay Description:Inhibition of topoisomerase II purified from HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

LigandPNGBDBM87351(m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...)
Affinity DataEC50:  720nMAssay Description:Inhibition of topoisomerase II purified from HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details
PDB3D3D Structure (crystal)
LigandPNGBDBM50213998(CHEMBL27542)
Affinity DataEC50: >2.40E+5nMAssay Description:Inhibition of topoisomerase II purified from HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

LigandPNGBDBM50213999(CHEMBL287205)
Affinity DataEC50: >2.60E+5nMAssay Description:Inhibition of topoisomerase II purified from HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

LigandPNGBDBM50214091(CHEMBL27233)
Affinity DataEC50:  330nMAssay Description:Inhibition of topoisomerase II purified from HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

LigandPNGBDBM50214092(CHEMBL27064)
Affinity DataEC50: >2.60E+5nMAssay Description:Inhibition of topoisomerase II purified from HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

LigandPNGBDBM50214093(CHEMBL281022)
Affinity DataEC50: >2.50E+5nMAssay Description:Inhibition of topoisomerase II purified from HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

LigandPNGBDBM50214094(CHEMBL30053)
Affinity DataEC50: >2.10E+5nMAssay Description:Inhibition of topoisomerase II purified from HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

LigandPNGBDBM50214148(CHEMBL283395)
Affinity DataEC50:  3.00E+3nMAssay Description:Inhibition of topoisomerase II purified from HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

LigandPNGBDBM50214149(CHEMBL29836)
Affinity DataEC50: >2.20E+5nMAssay Description:Inhibition of topoisomerase II purified from HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

LigandPNGBDBM50213799(CHEMBL440642)
Affinity DataEC50:  96nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

LigandPNGBDBM50213795(CHEMBL268458)
Affinity DataEC50:  330nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

LigandPNGBDBM50213809(CHEMBL7564)
Affinity DataEC50:  7.20E+3nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

LigandPNGBDBM50213292(CHEMBL7368)
Affinity DataEC50:  5.10E+3nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

LigandPNGBDBM50213297(CHEMBL8138)
Affinity DataEC50:  6.80E+3nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

LigandPNGBDBM50045706(1-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  1.70E+4nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

LigandPNGBDBM50213810(CHEMBL7534)
Affinity DataEC50:  1.20E+3nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

LigandPNGBDBM50213806(CHEMBL7831)
Affinity DataEC50:  1.40E+4nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

LigandPNGBDBM50213290(CHEMBL7216)
Affinity DataEC50:  9.10E+3nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

LigandPNGBDBM50213798(CHEMBL7618)
Affinity DataEC50:  5.10E+3nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

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