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TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM85115(Cyclophilin Inhibitor, 3a)
Affinity DataKd:  1.28E+5nMAssay Description:Electrospray mass spectrometry assay is a immunophilin-ligand binding assay which allows us to rapidly probe the affinity of potential inhibitors for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2012
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM85116(Cyclophilin Inhibitor, 15 | Cyclophilin Inhibitor,...)
Affinity DataKd:  7.26E+4nMAssay Description:Electrospray mass spectrometry assay is a immunophilin-ligand binding assay which allows us to rapidly probe the affinity of potential inhibitors for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2012
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM85117(Cyclophilin Inhibitor, 3c)
Affinity DataKd:  3.19E+4nMAssay Description:Electrospray mass spectrometry assay is a immunophilin-ligand binding assay which allows us to rapidly probe the affinity of potential inhibitors for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2012
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM85118(Cyclophilin Inhibitor, 3d)
Affinity DataKd:  8.51E+4nMAssay Description:Electrospray mass spectrometry assay is a immunophilin-ligand binding assay which allows us to rapidly probe the affinity of potential inhibitors for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2012
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM85119(Cyclophilin Inhibitor, 3e)
Affinity DataKd:  1.13E+5nMAssay Description:Electrospray mass spectrometry assay is a immunophilin-ligand binding assay which allows us to rapidly probe the affinity of potential inhibitors for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2012
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM85120(Cyclophilin Inhibitor, 3f)
Affinity DataKd:  1.33E+5nMAssay Description:Electrospray mass spectrometry assay is a immunophilin-ligand binding assay which allows us to rapidly probe the affinity of potential inhibitors for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2012
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM85115(Cyclophilin Inhibitor, 3a)
Affinity DataKd:  2.28E+4nMAssay Description:The promising ligand from the results obtained from ESI-MS assay are subjected to fluorescence in vitro assay. The fluorescence assay takes advantag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2012
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM85116(Cyclophilin Inhibitor, 15 | Cyclophilin Inhibitor,...)
Affinity DataKd:  1.59E+4nMAssay Description:The promising ligand from the results obtained from ESI-MS assay are subjected to fluorescence in vitro assay. The fluorescence assay takes advantag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2012
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM85117(Cyclophilin Inhibitor, 3c)
Affinity DataKd:  2.96E+4nMAssay Description:The promising ligand from the results obtained from ESI-MS assay are subjected to fluorescence in vitro assay. The fluorescence assay takes advantag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2012
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM85119(Cyclophilin Inhibitor, 3e)
Affinity DataKd:  2.19E+4nMAssay Description:The promising ligand from the results obtained from ESI-MS assay are subjected to fluorescence in vitro assay. The fluorescence assay takes advantag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2012
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM85116(Cyclophilin Inhibitor, 15 | Cyclophilin Inhibitor,...)
Affinity DataKd: >5.00E+4nMAssay Description:The promising ligand from the results obtained from ESI-MS assay are subjected to fluorescence in vitro assay. The fluorescence assay takes advantag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2012
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM93251(CypA Inhibitor, 1a)
Affinity DataKd:  2.43E+4nMpH: 7.4 T: 2°CAssay Description:CypA in vitro were determined by employing surface plasmon resonance (SPR) technology. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2013
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM93252(CypA Inhibitor, 1b)
Affinity DataKd:  3.07E+3nMpH: 7.4 T: 2°CAssay Description:CypA in vitro were determined by employing surface plasmon resonance (SPR) technology. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2013
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM93253(CypA Inhibitor, 1c)
Affinity DataKd:  212nMpH: 7.4 T: 2°CAssay Description:CypA in vitro were determined by employing surface plasmon resonance (SPR) technology. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2013
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM93254(CypA Inhibitor, 1d)
Affinity DataKd:  1.72E+4nMpH: 7.4 T: 2°CAssay Description:CypA in vitro were determined by employing surface plasmon resonance (SPR) technology. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2013
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM93255(CypA Inhibitor, 1e)
Affinity DataKd:  3.41E+3nMpH: 7.4 T: 2°CAssay Description:CypA in vitro were determined by employing surface plasmon resonance (SPR) technology. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2013
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM93256(CypA Inhibitor, 2a)
Affinity DataKd:  76.2nMpH: 7.4 T: 2°CAssay Description:CypA in vitro were determined by employing surface plasmon resonance (SPR) technology. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2013
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM93257(CypA Inhibitor, 2b)
Affinity DataKd:  2.88E+4nMpH: 7.4 T: 2°CAssay Description:CypA in vitro were determined by employing surface plasmon resonance (SPR) technology. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2013
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM93258(CypA Inhibitor, 3a)
Affinity DataKd:  8.18E+3nMpH: 7.4 T: 2°CAssay Description:CypA in vitro were determined by employing surface plasmon resonance (SPR) technology. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2013
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM93259(CypA Inhibitor, 3b)
Affinity DataKd:  1.08E+4nMpH: 7.4 T: 2°CAssay Description:CypA in vitro were determined by employing surface plasmon resonance (SPR) technology. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2013
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM93261(CypA Inhibitor, 4b)
Affinity DataKd:  2.73E+4nMpH: 7.4 T: 2°CAssay Description:CypA in vitro were determined by employing surface plasmon resonance (SPR) technology. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2013
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM93263(CypA Inhibitor, 4d)
Affinity DataKd:  3.08E+4nMpH: 7.4 T: 2°CAssay Description:CypA in vitro were determined by employing surface plasmon resonance (SPR) technology. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2013
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50339127((3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-25,30-d...)
Affinity DataKd:  2.20nMAssay Description:Binding affinity to human cyclophilin A by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50339126((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-24-sec-buty...)
Affinity DataKd:  7.5nMAssay Description:Binding affinity to human cyclophilin A by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50030494(CHEMBL3344503)
Affinity DataKd:  1.10nMAssay Description:Binding affinity to human cyclophilin A by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50030533(CHEMBL3344502)
Affinity DataKd:  1.10nMAssay Description:Binding affinity to human cyclophilin A by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50030493(CHEMBL3344501 | US9566312, Compound 2.17.4)
Affinity DataKd:  1.20nMAssay Description:Binding affinity to human cyclophilin A by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50030534(CHEMBL3344500 | US9566312, Compound 2.5.22)
Affinity DataKd:  1.80nMAssay Description:Binding affinity to human cyclophilin A by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50030535(CHEMBL3344499 | US9566312, Compound 2.5.26)
Affinity DataKd:  1.40nMAssay Description:Binding affinity to human cyclophilin A by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50030536(CHEMBL3344498 | US9566312, Compound 2.5.3)
Affinity DataKd:  2.5nMAssay Description:Binding affinity to human cyclophilin A by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50030538(CHEMBL3344497 | US9566312, Compound 2.5.18)
Affinity DataKd:  4nMAssay Description:Binding affinity to human cyclophilin A by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50030541(CHEMBL3344496 | US9566312, Compound 2.5.21)
Affinity DataKd:  1.90nMAssay Description:Binding affinity to human cyclophilin A by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50030542(CHEMBL3344495 | US9566312, Compound 2.5.2)
Affinity DataKd:  3.10nMAssay Description:Binding affinity to human cyclophilin A by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50030554(CHEMBL3344494 | US9566312, Compound 2.1)
Affinity DataKd:  1.70nMAssay Description:Binding affinity to human cyclophilin A by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50030555(CHEMBL3344493 | US9566312, Compound 2.10)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to human cyclophilin A by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50323721((3S,6S,9S,12R,15S,18S,21S,24S,27S,30S,33S)-27-(2-(...)
Affinity DataKd:  3.20nMAssay Description:Binding affinity to human cyclophilin A by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50044551(CHEMBL3327189)
Affinity DataKd: <60nMAssay Description:Binding affinity to cyclophilin A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50267744(4-(3-(4-Chlorophenyl)thioureido)-N-(thiazol-2-yl)b...)
Affinity DataKd:  5.10E+4nMAssay Description:Binding affinity to human cyclophilin A by intrinsic tryptophan fluorescence titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50267743(4-(3-(3-Chloro-4-methylphenyl)thioureido)-N-(thiaz...)
Affinity DataKd:  5.16E+4nMAssay Description:Binding affinity to human cyclophilin A by intrinsic tryptophan fluorescence titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50267741(4-(3-(3-Chloro-4-methylphenyl)thioureido)-N-(5-met...)
Affinity DataKd:  5.58E+4nMAssay Description:Binding affinity to human cyclophilin A by intrinsic tryptophan fluorescence titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50267742(4-(3-(4-Chlorophenyl)thioureido)-N-(4-methoxypheny...)
Affinity DataKd:  6.08E+4nMAssay Description:Binding affinity to human cyclophilin A by intrinsic tryptophan fluorescence titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50267547(1-(3-Chloro-4-methylphenyl)-3-(2-(2-(diethylamino)...)
Affinity DataKd:  7.33E+4nMAssay Description:Binding affinity to human cyclophilin A by intrinsic tryptophan fluorescence titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50267745(N-(Thiazol-2-yl)-4-(3-ptolylthioureido) benzenesul...)
Affinity DataKd:  7.69E+4nMAssay Description:Binding affinity to human cyclophilin A by intrinsic tryptophan fluorescence titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50267548(1-(3-Bromophenyl)-3-(2-(2-(diethylamino)-6-methyl-...)
Affinity DataKd:  7.93E+4nMAssay Description:Binding affinity to human cyclophilin A by intrinsic tryptophan fluorescence titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50267591(1-(4-Methoxyphenyl)-3-(3-oxo-1,3-dihydroisobenzofu...)
Affinity DataKd:  1.72E+5nMAssay Description:Binding affinity to human cyclophilin A by intrinsic tryptophan fluorescence titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50267549(1-(3-Bromophenyl)-3-(2-(2-(diethylamino)-6-methylp...)
Affinity DataKd:  2.01E+5nMAssay Description:Binding affinity to human cyclophilin A by intrinsic tryptophan fluorescence titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50267589(1-(4-Chlorophenyl)-3-(3-oxo-1,3-dihydroisobenzofur...)
Affinity DataKd:  2.22E+5nMAssay Description:Binding affinity to human cyclophilin A by intrinsic tryptophan fluorescence titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50267623(1-(4-Fluorophenyl)-3-(3-oxo-1,3-dihydroisobenzofur...)
Affinity DataKd:  2.27E+5nMAssay Description:Binding affinity to human cyclophilin A by intrinsic tryptophan fluorescence titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50267620(1-(3,5-Difluorophenyl)-3-(3-oxo-1,3-dihydroisobenz...)
Affinity DataKd:  5.13E+5nMAssay Description:Binding affinity to human cyclophilin A by intrinsic tryptophan fluorescence titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
The University of Edinburgh

LigandPNGBDBM50267659(4-(3-(3-Chlorophenyl)thioureido)-N-(5-methylisoxaz...)
Affinity DataKd:  7.96E+4nMAssay Description:Binding affinity to human cyclophilin A by intrinsic tryptophan fluorescence titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
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