Compile Data Set for Download or QSAR
Report error Found 512 of affinity data for UniProtKB/TrEMBL: P56726
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50196074(CHEMBL3919826)
Affinity DataEC50:  1.50E+3nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50196075(CHEMBL3894352)
Affinity DataEC50:  600nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50196076(CHEMBL3965788)
Affinity DataEC50:  900nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50196077(CHEMBL3947608)
Affinity DataEC50:  1.20E+3nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50324671(Purmorphamine | CHEMBL1221984)
Affinity DataEC50:  800nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50196078(CHEMBL3899175)
Affinity DataEC50:  1.20E+3nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50196079(CHEMBL3891055)
Affinity DataEC50:  3.60E+3nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50196080(CHEMBL3927217)
Affinity DataEC50:  360nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50196081(CHEMBL3971451)
Affinity DataEC50:  600nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50196082(CHEMBL3923290)
Affinity DataEC50:  5.80E+3nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50196083(CHEMBL3954578)
Affinity DataEC50:  800nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50393851(CHEMBL1221983)
Affinity DataEC50:  130nMAssay Description:Agonist activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50196084(CHEMBL3970506)
Affinity DataEC50:  700nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50196085(CHEMBL3941789)
Affinity DataEC50:  800nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50196086(CHEMBL3974265)
Affinity DataEC50:  2.00E+3nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50196087(CHEMBL3903318)
Affinity DataEC50:  6.50E+3nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50196088(CHEMBL3979766)
Affinity DataEC50:  3.40E+3nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50393851(CHEMBL1221983)
Affinity DataEC50:  30nMAssay Description:Agonist activity at Smo in mouse NIH/3T3 cells transfected with Gli-dependent firefly luciferase reporter assessed as stimulation of Gli transcriptio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50196089(CHEMBL3950627)
Affinity DataEC50:  4.90E+3nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50196090(CHEMBL3958271)
Affinity DataEC50:  3.10E+3nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50196091(CHEMBL3925255)
Affinity DataEC50:  2.60E+3nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50196092(CHEMBL3922897)
Affinity DataEC50:  2.40E+3nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50200480(CHEMBL3965352)
Affinity DataEC50:  24nMAssay Description:Inhibition of Smo in mouse Shh Light2 cells assessed as inhibition of SAG-induced Hh pathway activity by measuring SAG-EC50 at 50 nM measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50200480(CHEMBL3965352)
Affinity DataEC50:  47nMAssay Description:Inhibition of Smo in mouse Shh Light2 cells assessed as inhibition of SAG-induced Hh pathway activity by measuring SAG-EC50 at 100 nM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50200480(CHEMBL3965352)
Affinity DataEC50:  137nMAssay Description:Inhibition of Smo in mouse Shh Light2 cells assessed as inhibition of SAG-induced Hh pathway activity by measuring SAG-EC50 at 500 nM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50249522(2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(me...)
Affinity DataEC50:  4.70nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50388722(CHEMBL2059865)
Affinity DataEC50:  13nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50539182(CHEMBL4642917)
Affinity DataEC50:  7.5nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50388708(CHEMBL2059866)
Affinity DataEC50:  89nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50539183(CHEMBL4636352)
Affinity DataEC50:  23nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50388711(CHEMBL2059869)
Affinity DataEC50:  27nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50539184(CHEMBL4636369)
Affinity DataEC50:  2.90nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50388720(CHEMBL2059861)
Affinity DataEC50:  18nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50388709(CHEMBL2059867)
Affinity DataEC50:  6.70nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50539185(CHEMBL4637915)
Affinity DataEC50:  30nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50388719(CHEMBL2059860)
Affinity DataEC50:  39nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50388710(CHEMBL2059868)
Affinity DataEC50:  21nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50539186(CHEMBL4641050)
Affinity DataEC50:  6.80nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50539187(CHEMBL4632769)
Affinity DataEC50:  1nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50539188(CHEMBL4637222)
Affinity DataEC50:  2.60nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50539189(CHEMBL4640840)
Affinity DataEC50:  2.90nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50539190(CHEMBL4636326)
Affinity DataEC50:  17nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50539191(CHEMBL4638476)
Affinity DataEC50:  13nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50539192(CHEMBL4637218)
Affinity DataEC50:  3.10nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50539193(CHEMBL4639432)
Affinity DataEC50:  0.900nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50539194(CHEMBL4648026)
Affinity DataEC50:  1.10nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50539195(CHEMBL4647379)
Affinity DataEC50:  3.10nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50539196(CHEMBL4644674)
Affinity DataEC50:  0.800nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50539197(CHEMBL4644175)
Affinity DataEC50:  2.30nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50539198(CHEMBL4643226)
Affinity DataEC50:  1nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
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