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Report error Found 23 for UniProtKB: P54709
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444975(US10668094, Compound DtxMcP-(cyclic) | US10668094,...)
Affinity DataKi:  3.70nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
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TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444991(US10668094, Compound DMDMcB-(cyclic))
Affinity DataKi:  3.90nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
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TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444840(US10668094, Compound DtxcB-(cyclic) | US10668094, ...)
Affinity DataKi:  4nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
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TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444975(US10668094, Compound DtxMcP-(cyclic) | US10668094,...)
Affinity DataKi:  4.30nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
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TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444840(US10668094, Compound DtxcB-(cyclic) | US10668094, ...)
Affinity DataKi:  4.30nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
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TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444983(US10668094, Compound DBz-(cyclic))
Affinity DataKi:  5.60nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
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TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444977(US10668094, Compound DiB)
Affinity DataKi:  5.80nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
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TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444981(US10668094, Compound DEcP-(cyclic))
Affinity DataKi:  7.20nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
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TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444980(US10668094, Compound DcP-(cyclic))
Affinity DataKi:  8.10nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
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TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444989(US10668094, Compound DP)
Affinity DataKi:  9.80nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
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TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444979(US10668094, Compound DiP)
Affinity DataKi:  10.3nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
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TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM231660(DMe (11) | US10668094, Compound DMe)
Affinity DataKi:  10.8nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
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TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444994(US10668094, Compound DTMS-(silyl))
Affinity DataKi:  11.1nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
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TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444984(US10668094, Compound DcH-(cyclic))
Affinity DataKi:  11.7nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
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TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM231662(DMeCF3 (13) | US10668094, Compound DCF3)
Affinity DataKi:  12.4nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
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TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM231661(DEt (12) | US10668094, Compound DEt)
Affinity DataKi:  14.4nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
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TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444990(US10668094, Compound DtB)
Affinity DataKi:  16.3nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
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TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444978(US10668094, Compound DESA-(sulfonamide))
Affinity DataKi:  20.1nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
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TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444976(US10668094, Compound DESM-(sulfonyl))
Affinity DataKi:  24.7nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
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TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444996(US10668094, Compound DcPe-(cyclic))
Affinity DataKi:  27.6nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
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TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM46356(SMR000058529 | cid_441207 | MLS000069787 | DIGITOX...)
Affinity DataKi:  28.8nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
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PDB3D3D Structure (crystal)
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM46355(MLS000069819 | cid_2724385 | SMR000059217 | DIGOXI...)
Affinity DataKi:  42.8nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
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PDB3D3D Structure (crystal)
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444982(US10668094, Compound DMSM-(sulfonyl))
Affinity DataKi:  89nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent