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Report error Found 686 of affinity data for UniProtKB/TrEMBL: P53985
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50103571(CHEMBL3335793)
Affinity DataKd:  1.60nMAssay Description:Binding affinity to MCT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180637(CHEMBL3818005)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180638(CHEMBL3818980)
Affinity DataEC50:  55nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180639(CHEMBL3818923)
Affinity DataEC50:  60nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180640(CHEMBL3819278)
Affinity DataEC50:  520nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180641(CHEMBL3818095)
Affinity DataEC50:  24nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180642(CHEMBL3818476)
Affinity DataEC50:  420nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180643(CHEMBL3818311)
Affinity DataEC50:  0.800nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180644(CHEMBL3818991)
Affinity DataEC50:  500nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180645(CHEMBL3817951)
Affinity DataEC50:  0.800nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180646(CHEMBL3819279)
Affinity DataEC50:  100nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180647(CHEMBL3818777)
Affinity DataEC50:  0.160nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180648(CHEMBL3818150)
Affinity DataEC50:  0.800nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180649(CHEMBL3818851)
Affinity DataEC50:  4nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180650(CHEMBL3817902)
Affinity DataEC50:  11nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM22000(7-[(3-hydroxypropyl)sulfanyl]-2-methyl-4-(2-methyl...)
Affinity DataEC50:  5nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180651(CHEMBL3819158)
Affinity DataEC50:  690nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50092069(CHEMBL3582422 | US9296728, 20)
Affinity DataIC50: 8nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50092072(CHEMBL3582419 | US9296728, 14)
Affinity DataIC50: 9nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50092071(CHEMBL3582420 | US9296728, 18)
Affinity DataIC50: 11nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50608633(CHEMBL3582501)
Affinity DataIC50: 25nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50092070(CHEMBL3582421 | US9296728, 15)
Affinity DataIC50: 34nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM214697(US9296728, 19)
Affinity DataIC50: 37nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM214698(US9296728, 21)
Affinity DataIC50: 48nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM345287(2-[[1-[(2-Chlorophenyl)methyl]-5-[3- (cyclopropyl...)
Affinity DataIC50: 54.5nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM356766(US10214492, Example 130)
Affinity DataIC50: 55nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM546629(2-([1-[(2-Chlorophenyl)methyl]-5-(4- cyclopropoxyt...)
Affinity DataIC50: 55nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
Go to US Patent

TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50616340(CHEMBL5435709)
Affinity DataIC50: 81nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50616346(CHEMBL5419493)
Affinity DataIC50: 82nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM4350((2E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid ...)
Affinity DataIC50: 87nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM345271(1-[[5-(4-Chlorophenyl)-1-[(2- chlorophenyl)methyl...)
Affinity DataIC50: 100nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM345295(1-[[1-[(2-Chlorophenyl)methyl]-5-(3- methoxypheny...)
Affinity DataIC50: 100nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM356738(US10214492, Example 108 | US11292767, Example 108)
Affinity DataIC50: 102nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM356858(US10214492, Example 207 | US11292767, Example 207)
Affinity DataIC50: 102nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM356768(US10214492, Example 132 | US11292767, Example 132)
Affinity DataIC50: 104nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM22000(7-[(3-hydroxypropyl)sulfanyl]-2-methyl-4-(2-methyl...)
Affinity DataIC50: 105nMAssay Description:Inhibition of MCT1 (unknown origin) overexpressed in human MCF7 cells assessed as inhibition of transporter-mediated [14C]lactate transport after 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50616336(CHEMBL5401494)
Affinity DataIC50: 105nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50616339(CHEMBL5405329)
Affinity DataIC50: 105nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50616335(CHEMBL5394985)
Affinity DataIC50: 109nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50616343(CHEMBL5433941)
Affinity DataIC50: 109nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50616348(CHEMBL5409450)
Affinity DataIC50: 109nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50616337(CHEMBL5440350)
Affinity DataIC50: 112nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50055506(CHEMBL3326270)
Affinity DataIC50: 116nMAssay Description:Inhibition of MCT1 (unknown origin) overexpressed in human MCF7 cells assessed as inhibition of transporter-mediated [14C]lactate transport after 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50616338(CHEMBL5421503)
Affinity DataIC50: 135nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM356781(US10214492, Example 143 | US11292767, Example 143)
Affinity DataIC50: 152nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM356861(US10214492, Example 210 | US11292767, Example 210)
Affinity DataIC50: 154nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM356904(US10214492, Example 255 | US11292767, Example 255)
Affinity DataIC50: 154nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50055505(CHEMBL3326265)
Affinity DataIC50: 192nMAssay Description:Inhibition of MCT1 (unknown origin) overexpressed in human MCF7 cells assessed as inhibition of transporter-mediated [14C]lactate transport after 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50616334(CHEMBL5397576)
Affinity DataIC50: 193nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50616342(CHEMBL5427293)
Affinity DataIC50: 196nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
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