Compile Data Set for Download or QSAR
Report error Found 974 of affinity data for UniProtKB/TrEMBL: P50053
TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241201(CHEMBL4074975)
Affinity DataKd:  1.03E+5nMAssay Description:Binding affinity to full length recombinant human biotin-labeled KHK by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2019
Entry Details Article
PubMed
TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241205(CHEMBL1463512)
Affinity DataKd:  4.40E+4nMAssay Description:Binding affinity to full length recombinant human biotin-labeled KHK by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2019
Entry Details Article
PubMed
TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241206(CHEMBL1500542)
Affinity DataKd:  6.20E+4nMAssay Description:Binding affinity to full length recombinant human biotin-labeled KHK by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241207(CHEMBL4086173)
Affinity DataKd:  2.00E+4nMAssay Description:Binding affinity to full length recombinant human biotin-labeled KHK by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241206(CHEMBL1500542)
Affinity DataKd:  6.20E+4nMAssay Description:Binding affinity to recombinant His-tagged human KHK expressed in Escherichia coli in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241205(CHEMBL1463512)
Affinity DataKd:  4.40E+4nMAssay Description:Binding affinity to recombinant His-tagged human KHK expressed in Escherichia coli in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM655985(US20240067633, Isomer 2 of compound 3)
Affinity DataEC50:  37.4nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetKetohexokinase Isoform A(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM655985(US20240067633, Isomer 2 of compound 3)
Affinity DataEC50:  51.8nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM655986(US20240067633, Isomer 2 of compound 4)
Affinity DataEC50:  19.4nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM655987((S)-2-(1-(4-cyano-5,5-difluoro-3-(2-methylazetidin...)
Affinity DataEC50:  36.5nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetKetohexokinase Isoform A(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM655987((S)-2-(1-(4-cyano-5,5-difluoro-3-(2-methylazetidin...)
Affinity DataEC50:  35.2nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM655988(US20240067633, Isomer 1 of compound 8)
Affinity DataEC50:  58.6nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetKetohexokinase Isoform A(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM655988(US20240067633, Isomer 1 of compound 8)
Affinity DataEC50:  59.7nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM655989(2-((1R,5S,6R)-3-(7,7-difluoro-2-((S)-2-(methyl-d3)...)
Affinity DataEC50:  37.7nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM655990((S)-2-(1-(4-cyano-5,5-difluoro-3-(2-(methyl-d3)aze...)
Affinity DataEC50:  52.7nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM655991(US20240067633, Isomer 2 of compound 19)
Affinity DataEC50:  60.6nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM655992(US20240067633, Isomer 2 of compound 20)
Affinity DataEC50:  49.8nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM655993(US20240067633, Compound Control)
Affinity DataEC50:  123nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetKetohexokinase Isoform A(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM707376((2S,3R)-1-{5-chloro-4-[1-(1- methyl-3-azetidinyl)-...)
Affinity DataIC50: 0.200nMAssay Description:Determination of Human and Rat recombinant KHK-A and KHK-C isozyme IC50 ValuesAn assay reagent cocktail was prepared by combining NADH, water, TEA, K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50628740(CHEMBL5402865)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of KHK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM707376((2S,3R)-1-{5-chloro-4-[1-(1- methyl-3-azetidinyl)-...)
Affinity DataIC50: 0.856nMAssay Description:Determination of Human and Rat recombinant KHK-A and KHK-C isozyme IC50 ValuesAn assay reagent cocktail was prepared by combining NADH, water, TEA, K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM319582(US10174007, Example 1 | US10787438, Example 1 | US...)
Affinity DataIC50: 1nMAssay Description:Inhibition of 1 nM recombinant human N-terminal His-tagged KHKC expressed in Escherichia coli BL21 (DE3) using fructose as substrate preincubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM707378((2S,3R)-2-methyl-1-{5-methyl-4- [1-(1-methyl-3-aze...)
Affinity DataIC50: 1.05nMAssay Description:Determination of Human and Rat recombinant KHK-A and KHK-C isozyme IC50 ValuesAn assay reagent cocktail was prepared by combining NADH, water, TEA, K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM511679(US11083720, Compound C-1 | 4-(1-phenyl-1H-indazol-...)
Affinity DataIC50: 1.17nMAssay Description:Specific high-throughput screening assays were developed for KHK-C and KHK-A using recombinant proteins. Purified human recombinant KHK-C and KHK-A w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM319582(US10174007, Example 1 | US10787438, Example 1 | US...)
Affinity DataIC50: 1.5nMAssay Description:Compounds having an IC50 value less than 20 nM were examined in a second KHK assay, referred to as Assay B, using 10-fold less enzyme and measuring a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM319583(US10174007, Example 2 | US10787438, Example 2 | US...)
Affinity DataIC50: 1.5nMAssay Description:Compounds having an IC50 value less than 20 nM were examined in a second KHK assay, referred to as Assay B, using 10-fold less enzyme and measuring a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM319605([(1R,5S,6R)-3-{5-cyano-4-(1,1-difluoroethyl)-3-flu...)
Affinity DataIC50: 1.5nMAssay Description:Compounds having an IC50 value less than 20 nM were examined in a second KHK assay, referred to as Assay B, using 10-fold less enzyme and measuring a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM319582(US10174007, Example 1 | US10787438, Example 1 | US...)
Affinity DataIC50: 1.5nMAssay Description:Assay B, using 10-fold less enzyme and measuring absorbance for 3 hours to obtain IC50 values below the 10 nM lower limit of Assay A. Compounds were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2021
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM319583(US10174007, Example 2 | US10787438, Example 2 | US...)
Affinity DataIC50: 1.5nMAssay Description:Assay B, using 10-fold less enzyme and measuring absorbance for 3 hours to obtain IC50 values below the 10 nM lower limit of Assay A. Compounds were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2021
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM464138([(1R,5S,6R)-3-{5-cyano-4-(1,1-difluoroethyl)-3-flu...)
Affinity DataIC50: 1.5nMAssay Description:Assay B, using 10-fold less enzyme and measuring absorbance for 3 hours to obtain IC50 values below the 10 nM lower limit of Assay A. Compounds were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2021
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM319582(US10174007, Example 1 | US10787438, Example 1 | US...)
Affinity DataIC50: 1.5nMAssay Description:Assay B, using 10-fold less enzyme and measuring absorbance for 3 hours to obtain IC50 values below the 10 nM lower limit of Assay A. Compounds were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM319583(US10174007, Example 2 | US10787438, Example 2 | US...)
Affinity DataIC50: 1.5nMAssay Description:Assay B, using 10-fold less enzyme and measuring absorbance for 3 hours to obtain IC50 values below the 10 nM lower limit of Assay A. Compounds were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM494884(US10988463, Example 50 | [(1R,5S,6R)-3-{5-cyano-4-...)
Affinity DataIC50: 1.5nMAssay Description:Assay B, using 10-fold less enzyme and measuring absorbance for 3 hours to obtain IC50 values below the 10 nM lower limit of Assay A. Compounds were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM319582(US10174007, Example 1 | US10787438, Example 1 | US...)
Affinity DataIC50: 1.5nMAssay Description:Using 10-fold less enzyme and measuring absorbance for 3 hours to obtain IC50 values below the 10 nM lower limit of Assay A. Compounds were prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM319583(US10174007, Example 2 | US10787438, Example 2 | US...)
Affinity DataIC50: 1.5nMAssay Description:Using 10-fold less enzyme and measuring absorbance for 3 hours to obtain IC50 values below the 10 nM lower limit of Assay A. Compounds were prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM601403(US11634410, Example 50 | [(1R,5S,6R)-3-{5-cyano-4-...)
Affinity DataIC50: 1.5nMAssay Description:Using 10-fold less enzyme and measuring absorbance for 3 hours to obtain IC50 values below the 10 nM lower limit of Assay A. Compounds were prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM707387((2S,3R)-1-{6-(difluoromethyl)-5- methyl-4-[1-(1-me...)
Affinity DataIC50: 1.5nMAssay Description:Determination of Human and Rat recombinant KHK-A and KHK-C isozyme IC50 ValuesAn assay reagent cocktail was prepared by combining NADH, water, TEA, K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetKetohexokinase Isoform A(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM518444(US11124500, Example 35 | (2S,3R)-2-Methyl-1-[4-[1-...)
Affinity DataIC50: 1.59nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetKetohexokinase Isoform A(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM707370(2-(4-{2-[(S)-2-methyl-1- azetidinyl]-5-chloro-6- (...)
Affinity DataIC50: 1.80nMAssay Description:Determination of Human and Rat recombinant KHK-A and KHK-C isozyme IC50 ValuesAn assay reagent cocktail was prepared by combining NADH, water, TEA, K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetKetohexokinase Isoform A(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM707401((2S,3R)-1-{4-[1-(3-azetidinyl)-4- pyrazolyl]-6-(di...)
Affinity DataIC50: 1.90nMAssay Description:Determination of Human and Rat recombinant KHK-A and KHK-C isozyme IC50 ValuesAn assay reagent cocktail was prepared by combining NADH, water, TEA, K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389319(CHEMBL2063924)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM518423(US11124500, Example 17 | 6-[1-(Azetidin-3-yl)pyraz...)
Affinity DataIC50: 2nMAssay Description:Inhibition of KHK in human HepG2 cells incubated for 3 hrs by Rapidfire MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetKetohexokinase Isoform A(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM707387((2S,3R)-1-{6-(difluoromethyl)-5- methyl-4-[1-(1-me...)
Affinity DataIC50: 2.05nMAssay Description:Determination of Human and Rat recombinant KHK-A and KHK-C isozyme IC50 ValuesAn assay reagent cocktail was prepared by combining NADH, water, TEA, K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM707377((2S,3R)-1-{5-ethyl-4-[1-(1- methyl-3-azetidinyl)-4...)
Affinity DataIC50: 2.09nMAssay Description:Determination of Human and Rat recombinant KHK-A and KHK-C isozyme IC50 ValuesAn assay reagent cocktail was prepared by combining NADH, water, TEA, K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetKetohexokinase Isoform A(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM707391((2R,3R)-1-{4-[1-(1-methyl-3- azetidinyl)-4-pyrazol...)
Affinity DataIC50: 2.20nMAssay Description:Determination of Human and Rat recombinant KHK-A and KHK-C isozyme IC50 ValuesAn assay reagent cocktail was prepared by combining NADH, water, TEA, K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM319602([(1R,5S,6R)-3-{5-methyl-2-[(2S)-2-methylazetidin-1...)
Affinity DataIC50: 2.40nMAssay Description:Compounds having an IC50 value less than 20 nM were examined in a second KHK assay, referred to as Assay B, using 10-fold less enzyme and measuring a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM319602([(1R,5S,6R)-3-{5-methyl-2-[(2S)-2-methylazetidin-1...)
Affinity DataIC50: 2.40nMAssay Description:Assay B, using 10-fold less enzyme and measuring absorbance for 3 hours to obtain IC50 values below the 10 nM lower limit of Assay A. Compounds were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2021
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM494882(US10988463, Example 42 | [(1R,5S,6R)-3-{5-methyl-2...)
Affinity DataIC50: 2.40nMAssay Description:Assay B, using 10-fold less enzyme and measuring absorbance for 3 hours to obtain IC50 values below the 10 nM lower limit of Assay A. Compounds were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM319602([(1R,5S,6R)-3-{5-methyl-2-[(2S)-2-methylazetidin-1...)
Affinity DataIC50: 2.40nMAssay Description:Using 10-fold less enzyme and measuring absorbance for 3 hours to obtain IC50 values below the 10 nM lower limit of Assay A. Compounds were prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM319605([(1R,5S,6R)-3-{5-cyano-4-(1,1-difluoroethyl)-3-flu...)
Affinity DataIC50: 2.60nMAssay Description:A third KHK assay, referred to as Assay C, was performed at high fructose and ATP concentrations, conditions that would be more consistent with physi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent

Displayed 1 to 50 (of 974 total ) | Next | Last >>
Jump to: