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Report error Found 167 of affinity data for UniProtKB/TrEMBL: P49654
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118222(MRS 2257)
Affinity DataEC50:  22nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 3 (P2X3) at 3 uM, expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50257829(Ro-51 | 2-(4-amino-5-(5-iodo-2-isopropyl-4-methoxy...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at rat P2X3 receptor expressed in CHO cells by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM266545(US9718790, I-2291)
Affinity DataIC50: 3nMpH: 7.5Assay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The cells stably expressing rat P2X3 were seeded in a 96-we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2018
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50580225(CHEMBL5084053)
Affinity DataIC50: 3.80nMAssay Description:Antagonist activity at rat P2X3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM271665(US10065941, Compound R-009 | US9732060, Compound R...)
Affinity DataIC50: 4nMAssay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The C6BU-1 cells were seeded in a 96-well microtiter plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM271665(US10065941, Compound R-009 | US9732060, Compound R...)
Affinity DataIC50: 4nMAssay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The C6BU-1 cells were seeded in a 96-well microtiter plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM271626(US10065941, Compound I-127 | US9732060, Compound I...)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at rat P2X3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM265250(US9718790, I-1788)
Affinity DataIC50: 5nMpH: 7.5Assay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The cells stably expressing rat P2X3 were seeded in a 96-we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2018
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM265052(US9718790, I-1679)
Affinity DataIC50: 6nMpH: 7.5Assay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The cells stably expressing rat P2X3 were seeded in a 96-we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2018
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM271501(US10065941, Compound I-002 | US9732060, Compound I...)
Affinity DataIC50: 6nMAssay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The C6BU-1 cells were seeded in a 96-well microtiter plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM271675(US10065941, Compound R-014 | US9732060, Compound R...)
Affinity DataIC50: 6nMAssay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The C6BU-1 cells were seeded in a 96-well microtiter plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM271501(US10065941, Compound I-002 | US9732060, Compound I...)
Affinity DataIC50: 6nMAssay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The C6BU-1 cells were seeded in a 96-well microtiter plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50563052(CHEMBL4748113)
Affinity DataIC50: 6.10nMAssay Description:Antagonist activity at rat P2X3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50413367(CHEMBL523173)
Affinity DataIC50: 6.30nMAssay Description:Antagonist activity at rat P2X3 receptor expressed in CHO cells by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50413347(CHEMBL494353)
Affinity DataIC50: 6.30nMAssay Description:Antagonist activity at rat P2X3 receptor expressed in CHO cells by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50413370(CHEMBL495204)
Affinity DataIC50: 6.30nMAssay Description:Antagonist activity at rat recombinant P2X3 receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50580221(CHEMBL5073093)
Affinity DataIC50: 7.70nMAssay Description:Antagonist activity at rat P2X3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50413346(CHEMBL494160)
Affinity DataIC50: 7.90nMAssay Description:Antagonist activity at rat P2X3 receptor expressed in CHO cells by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM271685(US10065941, Compound R-019 | US9732060, Compound R...)
Affinity DataIC50: 8nMAssay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The C6BU-1 cells were seeded in a 96-well microtiter plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM271721(US10065941, Compound R-037 | US9732060, Compound R...)
Affinity DataIC50: 8nMAssay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The C6BU-1 cells were seeded in a 96-well microtiter plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM271539(US10065941, Compound I-130 | US10065941, Compound ...)
Affinity DataIC50: 9nMAssay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The C6BU-1 cells were seeded in a 96-well microtiter plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM271599(US10065941, Compound I-100 | US9732060, Compound I...)
Affinity DataIC50: 9nMAssay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The C6BU-1 cells were seeded in a 96-well microtiter plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50413367(CHEMBL523173)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat P2X3 receptor expressed in CHO cells by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50257636(5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat P2X3 receptor expressed in CHO cells by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50257636(5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat P2X3 receptor expressed in CHO cells by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50413356(CHEMBL492933)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat P2X3 receptor expressed in CHO cells by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50413364(CHEMBL492300)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat P2X3 receptor expressed in CHO cells by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50413349(CHEMBL494582)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat P2X3 receptor expressed in CHO cells by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50257636(5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat recombinant P2X3 receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM271612(US10065941, Compound I-113 | US9732060, Compound I...)
Affinity DataIC50: 10nMAssay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The C6BU-1 cells were seeded in a 96-well microtiter plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM271518(US10065941, Compound I-019 | US9732060, Compound I...)
Affinity DataIC50: 11nMAssay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The C6BU-1 cells were seeded in a 96-well microtiter plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM271521(US10065941, Compound I-022 | US9732060, Compound I...)
Affinity DataIC50: 11nMAssay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The C6BU-1 cells were seeded in a 96-well microtiter plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50413345(CHEMBL494159)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at rat P2X3 receptor expressed in CHO cells by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50413357(CHEMBL492934)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at rat P2X3 receptor expressed in CHO cells by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50413366(CHEMBL492907)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at rat P2X3 receptor expressed in CHO cells by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM266400(US9718790, I-0837)
Affinity DataIC50: 19nMpH: 7.5Assay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The cells stably expressing rat P2X3 were seeded in a 96-we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2018
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50413395(CHEMBL495203)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at rat recombinant P2X3 receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM266545(US9718790, I-2291)
Affinity DataIC50: 20nMpH: 7.5Assay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The cells stably expressing rat P2X3 were seeded in a 96-we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2018
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM265052(US9718790, I-1679)
Affinity DataIC50: 23nMpH: 7.5Assay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The cells stably expressing rat P2X3 were seeded in a 96-we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2018
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50102299(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonomethyl-p...)
Affinity DataIC50: 25nMAssay Description:Inhibition of inward ion current elicited by ATP was determined at recombinant P2X3 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50413382(CHEMBL494833)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at rat recombinant P2X3 receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50413394(CHEMBL448525)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at rat recombinant P2X3 receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50415550(Ro-85 | CHEMBL599760)
Affinity DataIC50: 31.6nMAssay Description:Antagonist activity at rat P2X3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50102300([4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonomethyl-...)
Affinity DataIC50: 36nMAssay Description:Inhibition of inward ion current elicited by ATP was determined at recombinant P2X3 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50415553(CHEMBL605130)
Affinity DataIC50: 39.8nMAssay Description:Antagonist activity at rat P2X3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50415601(CHEMBL598103)
Affinity DataIC50: 39.8nMAssay Description:Antagonist activity at rat P2X3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50413377(CHEMBL494176)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at rat recombinant P2X3 receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50413400(CHEMBL521983)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at rat recombinant P2X3 receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM266400(US9718790, I-0837)
Affinity DataIC50: 44nMpH: 7.5Assay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The cells stably expressing rat P2X3 were seeded in a 96-we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2018
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50413352(CHEMBL443930)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at rat P2X3 receptor expressed in CHO cells by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
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