Compile Data Set for Download or QSAR
Report error Found 46 of affinity data for UniProtKB/TrEMBL: P47824
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118226(PAPET-ATP | CHEMBL337062)
Affinity DataEC50:  98nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1) at 1 uM, expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118211(cid_23675739 | CHEMBL133576 | Acid Blue 129 | sodi...)
Affinity DataKd: >1.00E+5nMAssay Description:The compound was evaluated for antagonist activity against P2X purinoceptor 1 (P2X1) like receptor from rat vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118222(MRS 2257)
Affinity DataEC50:  5nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1) at 1 uM, expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118216((4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl di...)
Affinity DataEC50:  3.00E+3nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50064800(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataEC50:  43nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118215(Ip5I | CHEMBL1628528)
Affinity DataEC50:  1.5nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50064803(MRS 2220 | 3-Methyl-7-oxo-5,9-dihydro-6,8-dioxa-2-...)
Affinity DataEC50:  5.90E+3nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM85043(CHEMBL69234 | CAS_149017-66-3 | NSC_6093163 | PPAD...)
Affinity DataEC50:  99nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1) at 1 uM, expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118231(Cibachron Blue 3GA | CHEMBL134193)
Affinity DataKd:  1.60E+3nMAssay Description:Dissociation constant of the compound at P2X purinoceptor 1 (P2X1) from rat vas deferens was reportedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118237(Uniblue A | CHEMBL130059)
Affinity DataKd:  800nMAssay Description:Dissociation constant at P2X purinoceptor 1 from guinea pig taenia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118240(((2R,3S,4R,5R)-5-(6-amino-2-(hexylthio)-9H-purin-9...)
Affinity DataEC50:  840nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1) at 1 uM, expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50064803(MRS 2220 | 3-Methyl-7-oxo-5,9-dihydro-6,8-dioxa-2-...)
Affinity DataEC50:  5.90E+3nMAssay Description:Compound was tested in a functional ion channel assay of ATP-induced current at recombinant rat P2X1 receptor expressed in Xenopus oocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50064803(MRS 2220 | 3-Methyl-7-oxo-5,9-dihydro-6,8-dioxa-2-...)
Affinity DataEC50:  1.02E+4nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118244(PPNDS | CHEMBL131091)
Affinity DataEC50:  14nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50336799(Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...)
Affinity DataEC50:  1.00E+3nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1) at 1 uM, expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50240455(CHEMBL1253351)
Affinity DataIC50: 0.280nMAssay Description:Antagonist activity at rat P2X1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50540410(CHEMBL337395)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at rat P2X1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50102298(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonomethyl-p...)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50102295(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50102299(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonomethyl-p...)
Affinity DataIC50: 11nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50102300([4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonomethyl-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118221(alpha,beta-meATP | DIPHOSPHOMETHYLPHOSPHONIC ACID ...)
Affinity DataIC50: 14nMAssay Description:Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50102301(4-[4-Formyl-5-hydroxy-6-methyl-3-(2-phosphono-ethy...)
Affinity DataIC50: 20nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50102296(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonomethyl-p...)
Affinity DataIC50: 37nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50102297([2-(3,5-Bis-phosphonomethyl-phenylazo)-4-formyl-5-...)
Affinity DataIC50: 42nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50102304(Phosphoric acid mono-(4-formyl-5-hydroxy-6-methyl-...)
Affinity DataIC50: 42nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50102295(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50: 43nMAssay Description:Antagonist activity at recombinant rat P2X1 receptor expressed in Xenopus oocytes assessed as ion flux stimulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50064800(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50: 43nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM85043(CHEMBL69234 | CAS_149017-66-3 | NSC_6093163 | PPAD...)
Affinity DataIC50: 99nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50336781(Disodium 1-Amino-4-[3-(4,6-dichloro[1,3,5]triazine...)
Affinity DataIC50: 422nMAssay Description:Antagonist activity against rat P2X1 receptor expressed in Xenopus laevis oocyte assessed as inhibition of alpha, beta-meATP-induced inward current b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at rat P2X1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50540409(CHEBI:34941 | CHEMBL69234)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at rat P2X1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118245(MG 40-3 | CHEMBL133572)
Affinity DataIC50: 1.60E+3nMAssay Description:The compound was evaluated for antagonist activity against P2X purinoceptor 1 (P2X1) like receptor from rat vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50168286(1H-Benzoimidazole-2-carboxylic acid [(R)-1-((1S,2R...)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at rat P2X1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)
Affinity DataIC50: 4.68E+3nMAssay Description:Antagonist activity at P2X1 receptor in rat vas deferens assessed as inhibition of alpha/beta-meATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50336781(Disodium 1-Amino-4-[3-(4,6-dichloro[1,3,5]triazine...)
Affinity DataIC50: 4.70E+3nMAssay Description:Antagonist activity at P2X1 receptor in rat vas deferens assessed as inhibition of alphabeta me-ATP-induced responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118237(Uniblue A | CHEMBL130059)
Affinity DataIC50: 7.50E+3nMAssay Description:The compound was evaluated for antagonist activity against P2X purinoceptor 1 (P2X1) from rat vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118218(Disodium 1-amino-4-[4-(4,6-dichloro-[1,3,5]triazin...)
Affinity DataIC50: 8.80E+3nMAssay Description:The compound was evaluated for antagonist activity against P2X purinoceptor 1 (P2X1) like receptor from rat vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118231(Cibachron Blue 3GA | CHEMBL134193)
Affinity DataIC50: 9.60E+3nMAssay Description:The compound was evaluated for antagonist activity against P2X purinoceptor 1 (P2X1) from rat vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50064801(2-(4,7-Dihydroxy-3-methyl-7-oxo-5,9-dihydro-6,8-di...)
Affinity DataIC50: 1.02E+4nMAssay Description:Compound was tested in a functional ion channel assay of ATP-induced current at recombinant rat P2X1 receptor expressed in Xenopus oocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50064801(2-(4,7-Dihydroxy-3-methyl-7-oxo-5,9-dihydro-6,8-di...)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50064800(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50: 4.25E+4nMAssay Description:Compound was tested in a functional ion channel assay of ATP-induced current at recombinant rat P2X1 receptor expressed in Xenopus oocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM85043(CHEMBL69234 | CAS_149017-66-3 | NSC_6093163 | PPAD...)
Affinity DataIC50: 9.85E+4nMAssay Description:Compound was tested in a functional ion channel assay of ATP-induced current at recombinant rat P2X1 receptor expressed in Xenopus oocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50000029(suramin | SURAMIN HEXASODIUM | CHEMBL265502 | 4-Me...)
Affinity DataKi:  50nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM85682(CAS_5311315 | NSC_5311315 | NF279)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM85730(NSC_5311313 | CAS_5311313 | NF023)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2012
Entry Details Article
PubMed