Compile Data Set for Download or QSAR
Report error Found 6893 of affinity data for UniProtKB/TrEMBL: P43490
TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572541(US11452717, Example 136 | Ethyl 4-(3-((1H-imidazol...)
Affinity DataEC50: >2.00E+4nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM50569519(CHEMBL4850097 | US11452717, Compound TableB-1.16)
Affinity DataEC50: >2.00E+4nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572543(US11452717, Compound TableB-1.17 | Ethyl 4-(3-((3-...)
Affinity DataEC50: >2.00E+4nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572544(US11452717, Compound TableB-1.18 | Ethyl 4-(3-((1-...)
Affinity DataEC50: >2.00E+4nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM50569522(CHEMBL4867843 | US11452717, Compound TableB-1.19)
Affinity DataEC50: >2.00E+4nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572546(US11452717, Compound TableB-1.20 | Ethyl 4-(3-((1-...)
Affinity DataEC50: >2.00E+4nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572547(US11452717, Compound TableB-1.21 | Ethyl 4-(3-((1-...)
Affinity DataEC50: >2.00E+4nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572548(US11452717, Example 255 | 4-[3-(1H-Pyrazol-4-ylmet...)
Affinity DataEC50:  3.50E+3nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572549(US11452717, Example 256 | N-Benzyl-4-[3-(1H-pyrazo...)
Affinity DataEC50:  1.05E+3nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572550(US11452717, Example 257 | 1-[4-(3,4-Dihydro-1H-iso...)
Affinity DataEC50: <100nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572551(US11452717, Compound TableB-1.25 | 1-[4-(8-Oxa-3-a...)
Affinity DataEC50:  1.05E+3nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572552(US11452717, Compound TableB-1.26 | N-Cyclobutylmet...)
Affinity DataEC50:  1.05E+3nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572553(US11452717, Compound TableB-1.27 | N-Phenyl-4-[3-(...)
Affinity DataEC50:  1.05E+3nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572554(US11452717, Compound TableB-1.28 | N-Cyclopentyl-N...)
Affinity DataEC50:  1.05E+3nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572555(US11452717, Compound TableB-1.29 | N-Benzyl-N-isop...)
Affinity DataEC50: <100nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572556(US11452717, Compound TableB-1.30 | N-Benzyl-N-isop...)
Affinity DataEC50: <100nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572557(US11452717, Compound TableB-1.31 | N-Benzyl-N-isop...)
Affinity DataEC50: >2.00E+4nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572558(US11452717, Compound TableB-1.32 | N-Benzyl-N-isop...)
Affinity DataEC50: <100nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572559(US11452717, Compound TableB-1.33 | 1-[4-(3,4-Dihyd...)
Affinity DataEC50:  1.05E+3nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572560(US11452717, Compound TableB-1.34 | N-(3-Methoxy-be...)
Affinity DataEC50:  1.05E+3nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572561(US11452717, Compound TableB-1.35 | N-(2-Chloro-ben...)
Affinity DataEC50: <100nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572562(US11452717, Compound TableB-1.36 | N-(2-Methoxy-be...)
Affinity DataEC50: <100nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572563(US11452717, Compound TableB-1.37 | N-(4-Methoxy-be...)
Affinity DataEC50: <100nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572564(US11452717, Compound TableB-1.38 | N-(4-Chloro-ben...)
Affinity DataEC50:  1.05E+3nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572565(US11452717, Compound TableB-1.39 | N-Benzyl-4-(3-o...)
Affinity DataEC50:  1.05E+3nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572566(US11452717, Compound TableB-1.40 | 1-[4-(3,4-Dihyd...)
Affinity DataEC50:  1.05E+3nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572567(US11452717, Compound TableB-1.41 | 1-[4-(3,4-Dihyd...)
Affinity DataEC50: >2.00E+4nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572568(US11452717, Example 308 | 1-[4-(3-Chloro-benzenesu...)
Affinity DataEC50: <100nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572569(US11452717, Example 309 | 1-[4-(2-Chloro-benzenesu...)
Affinity DataEC50: <100nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572570(US11452717, Example 310 | BDBM50569539 | 1-[4-(4-C...)
Affinity DataEC50: <100nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572571(US11452717, Example 313 | 1-[4-(2-Methoxy-benzenes...)
Affinity DataEC50: <100nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572572(US11452717, Example 314 | 1-[4-(3-Methoxy-benzenes...)
Affinity DataEC50: <100nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM50569540(CHEMBL4868976 | US11452717, Compound TableB-1.47)
Affinity DataEC50: <100nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM50569538(CHEMBL4859010 | US11452717, Compound TableB-1.48)
Affinity DataEC50: <100nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572575(US11452717, Example 320 | 1-[4-(4-Methoxy-benzenes...)
Affinity DataEC50: <100nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572576(US11452717, Compound TableB-1.50 | N-[4-(3-Oxazol-...)
Affinity DataEC50:  1.05E+3nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572577(US11452717, Example 340 | N-Oxazol-5-ylmethyl-2-(4...)
Affinity DataEC50:  1.05E+3nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572578(US11452717, Example 341 | N-{4-[3-(1H-Pyrazol-4-yl...)
Affinity DataEC50: <100nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572579(US11452717, Example 342 | N-(4-(3-((1H-pyrazol-4-y...)
Affinity DataEC50: <100nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572580(US11452717, Example 343 | N-(4-{3-[1-(4-Methoxy-be...)
Affinity DataEC50: >2.00E+4nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572581(US11452717, Compound TableB-2.1 | 1-(4-Fluoropheny...)
Affinity DataEC50: >2.00E+4nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572582(US11452717, Compound TableB-2.2 | 1-(4-Chloropheny...)
Affinity DataEC50:  1.25E+4nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572583(US11452717, Compound TableB-2.3 | 1-(Pyridin-4-ylm...)
Affinity DataEC50: >2.00E+4nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572584(US11452717, Compound TableB-2.4 | Ethyl 2-(3-(pyri...)
Affinity DataEC50: >2.00E+4nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572585(US11452717, Compound TableB-2.5 | Ethyl 3-(3-(pyri...)
Affinity DataEC50:  1.25E+4nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572586(US11452717, Compound TableB-2.6 | 1-(Pyridin-4-ylm...)
Affinity DataEC50:  1.25E+4nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
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Date in BDB:
12/4/2022
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572587(US11452717, Compound TableB-2.7 | 1-(Pyridin-4-ylm...)
Affinity DataEC50: >2.00E+4nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
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Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572588(US11452717, Compound TableB-2.8 | 1-(4-Methoxyphen...)
Affinity DataEC50: >2.00E+4nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572589(US11452717, Compound TableB-2.9 | N,N-diethyl-4-(3...)
Affinity DataEC50: >2.00E+4nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572590(US11452717, Compound TableB-2.10 | 4-(3-(Pyridin-4...)
Affinity DataEC50:  3.50E+3nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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