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Report error Found 38 of affinity data for UniProtKB/TrEMBL: P43367
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50503849(CHEMBL4590466)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant porcine calpain 2 protease using BODIPY-FL casein as substrate measured at 30 secs time interval for 30 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189833((S)-N-butyl-3-((S)-2-(4-fluorophenylsulfonamido)-3...)
Affinity DataIC50: 21nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50503846(CHEMBL4540394)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant porcine calpain 2 protease using BODIPY-FL casein as substrate measured at 30 secs time interval for 30 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50503847(CHEMBL4574306)
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant porcine calpain 2 protease using BODIPY-FL casein as substrate measured at 30 secs time interval for 30 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50114340(N-(4-fluorophenylsulfonyl)-L-valyl-L-leucinal | (S...)
Affinity DataIC50: 49nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50263559(2-(2-methoxyethoxy)ethyl (S)-1-((S)-4-(cyclopropyl...)
Affinity DataIC50: 99nMAssay Description:Inhibition of pig kidney m-calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50263560(2-methoxyethyl (S)-1-((S)-4-(cyclopropylamino)-3,4...)
Affinity DataIC50: 100nMAssay Description:Inhibition of pig kidney m-calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50263561(2-(2-(2-methoxyethoxy)ethoxy)ethyl (S)-1-((S)-4-(c...)
Affinity DataIC50: 120nMAssay Description:Inhibition of pig kidney m-calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189825((2S)-2-((((4-cyanophenyl)amino)thioxomethyl)amino)...)
Affinity DataIC50: 120nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50503845(CHEMBL4531762)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant porcine calpain 2 protease using BODIPY-FL casein as substrate measured at 30 secs time interval for 30 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50263613(2-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)ethyl (S)-1...)
Affinity DataIC50: 170nMAssay Description:Inhibition of pig kidney m-calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189834((2S)-2-((((3-cyanophenyl)amino)thioxomethyl)amino)...)
Affinity DataIC50: 170nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189832((2S)-4-methyl-2-((((4-methylphenyl)amino)thioxomet...)
Affinity DataIC50: 170nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189835((2S)-2-((((4-fluorophenyl)amino)thioxomethyl)amino...)
Affinity DataIC50: 190nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189828(SNJ-1715 | 1-((S)-1-((3S)-2-hydroxy-tetrahydrofura...)
Affinity DataIC50: 190nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50263558(2-(2-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)ethoxy)e...)
Affinity DataIC50: 190nMAssay Description:Inhibition of pig kidney m-calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189827((2S)-2-((((4-methoxyphenyl)amino)thioxomethyl)amin...)
Affinity DataIC50: 200nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189822((2S)-2-((benzylamino)thioxomethyl)amino)-4-methyl-...)
Affinity DataIC50: 240nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189830((2S)-4-methyl-2-((((2-methylphenyl)amino)thioxomet...)
Affinity DataIC50: 250nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189831((2S)-4-methyl-2-((((3-methylphenyl)amino)thioxomet...)
Affinity DataIC50: 340nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189823((2S,3S)-3-methyl-2-(((phenylamino)thioxomethyl)ami...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189829((2S)-3-methyl-2-(((phenylamino)thioxomethyl)amino)...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189826((S)-2-(4-fluorophenylsulfonamido)-N-((3S)-2-hydrox...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50503848(CHEMBL4475662)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of recombinant porcine calpain 2 protease using BODIPY-FL casein as substrate measured at 30 secs time interval for 30 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189824(N-(1-cyano-3-methylbutyl)-2-((4-fluorophenyl)sulfo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50084684({3-Methyl-1-[1-(3-morpholin-4-yl-propylaminooxalyl...)
Affinity DataKi:  41nMAssay Description:Inhibition of porcine kidney calpain 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50326304(3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(6-amino-...)
Affinity DataKi:  68nMAssay Description:Inhibition of porcine kidney calpain 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50326303(3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(6-amino-...)
Affinity DataKi:  70nMAssay Description:Inhibition of porcine kidney calpain 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50326300(3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(6-amino-...)
Affinity DataKi:  77nMAssay Description:Inhibition of porcine kidney calpain 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50326298(3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(6-amino-...)
Affinity DataKi:  209nMAssay Description:Inhibition of porcine kidney calpain 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50326302(3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(4-methyl...)
Affinity DataKi:  286nMAssay Description:Inhibition of porcine kidney calpain 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50326301(3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(4-amino-...)
Affinity DataKi:  438nMAssay Description:Inhibition of porcine kidney calpain 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50326306(3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(dimethyl...)
Affinity DataKi:  844nMAssay Description:Inhibition of porcine kidney calpain 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50326299(3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(4-amino-...)
Affinity DataKi:  1.14E+3nMAssay Description:Inhibition of porcine kidney calpain 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50326305(3-(Benzyloxycarbonyl-L-leucylamino)-N-(2-(dimethyl...)
Affinity DataKi:  3.52E+3nMAssay Description:Inhibition of porcine kidney calpain 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50326307(3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(4-methyl...)
Affinity DataKi:  6.36E+3nMAssay Description:Inhibition of porcine kidney calpain 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50074050(3-(1-Benzyloxycarbonyl-3-methyl-butylcarbamoyl)-1-...)
Affinity DataKi:  4.20E+4nMAssay Description:Inhibition constant for the non time dependent inhibition of calpain 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50074050(3-(1-Benzyloxycarbonyl-3-methyl-butylcarbamoyl)-1-...)
Affinity DataKi:  4.20E+4nMAssay Description:Inhibition constant for the non time dependent inhibition of Calpain 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed