Compile Data Set for Download or QSAR
Report error Found 3 of affinity data for UniProtKB/TrEMBL: P31938
TargetDual specificity mitogen-activated protein kinase kinase 1(Mouse)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM104963(CHEMBL507361 | US8575391, Q | US11147816, PD032590...)
Affinity DataIC50: 0.330nMAssay Description:Inhibition of MEK1 in mouse colon 26 cells assessed as reduction in ERK1/2 phosphorylation after 1 hr by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2020
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Mouse)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50170831(N*6*-Cyclohexyl-N*2*-(4-morpholin-4-yl-phenyl)-9H-...)
Affinity DataIC50: 8nMAssay Description:Inhibition of MEK1 in mouse C2C12 by ERK2 phosphorylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Mouse)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50180839(CHEMBL1998165)
Affinity DataIC50: 20nMAssay Description:Inhibition of MEK1 in mouse C26 cells assessed as inhibition of ERK1/2 phosphorylation incubated for 1 hr by Western blottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed