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Report error Found 1131 for UniProtKB: P31421
TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50102128((2R,4R)-4-amino-1-(carboxymethyl)pyrrolidine-2,4-d...)
Affinity DataEC50:  610nMAssay Description:Effective concentration required for partial agonistic activity at Metabotropic glutamate receptor 2; Partial agonistMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50052398(2R, 4R-APDC | (2R,4R)-APDC | CHEMBL40086 | (2R,4R)...)
Affinity DataEC50:  480nMAssay Description:Effective concentration required for agonistic activity at Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50102122((2R,4R)-4-amino-1-(4-aminobenzyl)pyrrolidine-2,4-d...)
Affinity DataEC50:  2.30E+3nMAssay Description:Effective concentration required for partial agonistic activity at Metabotropic glutamate receptor 2; Partial agonistMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50102119((2R,4R)-4-amino-1-(3-hydroxybenzyl)pyrrolidine-2,4...)
Affinity DataEC50:  9.50E+5nMAssay Description:Effective concentration required for agonistic activity at Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50102113((2R,4R)-4-amino-1-(pyridin-2-ylmethyl)pyrrolidine-...)
Affinity DataEC50:  3.70E+4nMAssay Description:Effective concentration required for agonistic activity at Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50102115((2R,4R)-4-amino-1-(2-aminobenzyl)pyrrolidine-2,4-d...)
Affinity DataEC50:  3.50E+4nMAssay Description:Effective concentration required for agonistic activity at Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50102118((2R,4R)-4-amino-1-(2-carboxybenzyl)pyrrolidine-2,4...)
Affinity DataEC50:  3.30E+4nMAssay Description:Effective concentration required for agonistic activity at Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50102124((2R,4R)-4-amino-1-(4-carboxybenzyl)pyrrolidine-2,4...)
Affinity DataEC50:  4.70E+3nMAssay Description:Effective concentration required for partial agonistic activity at Metabotropic glutamate receptor 2; Partial agonistMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50102120((2R,4R)-4-amino-1-(2-hydroxybenzyl)pyrrolidine-2,4...)
Affinity DataEC50:  6.10E+3nMAssay Description:Effective concentration required for agonistic activity at Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50102114((2R,4R)-4-amino-1-(4-hydroxybenzyl)pyrrolidine-2,4...)
Affinity DataEC50:  2.40E+4nMAssay Description:Effective concentration required for agonistic activity at Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50102116((2R,4R)-4-amino-1-(2-nitrobenzyl)pyrrolidine-2,4-d...)
Affinity DataEC50:  4.00E+3nMAssay Description:Effective concentration required for agonistic activity at Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50102117((2R,4R)-4-amino-1-(4-nitrobenzyl)pyrrolidine-2,4-d...)
Affinity DataEC50:  1.60E+5nMAssay Description:Effective concentration required for agonistic activity at Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50100942((2S,4S)-2-ammonio-4-carboxy-4-hydroxybutanoate)
Affinity DataEC50:  1.37E+5nMAssay Description:Agonist activity in rat at mGlu2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50100941((2S,4R)-2-ammonio-4-carboxy-4-hydroxybutanoate)
Affinity DataEC50:  1.61E+5nMAssay Description:Agonist activity in rat at mGlu2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM17657(L-Glutamic acid | L-Glu | (2S)-2-aminopentanedioic...)
Affinity DataEC50:  1.60E+4nMAssay Description:Agonist activity in rat at Metabotropic glutamate receptor 2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM66976(SMR001230688 | trans-( )-ACPD monohydrate | cid_16...)
Affinity DataEC50:  5.00E+3nMAssay Description:Tested for the agonistic activity against Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50056272((2S,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxy...)
Affinity DataEC50:  35nMAssay Description:Tested for the agonistic activity against Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50052398(2R, 4R-APDC | (2R,4R)-APDC | CHEMBL40086 | (2R,4R)...)
Affinity DataEC50:  300nMAssay Description:Tested for the agonistic activity against Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50052398(2R, 4R-APDC | (2R,4R)-APDC | CHEMBL40086 | (2R,4R)...)
Affinity DataEC50:  200nMAssay Description:Agonistic activity evaluated in CHO(Chinese hamster ovary) cells expressing mGluR2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50078596(4-Amino-2,4-dicarboxy-pyrrolidin-1-yl-ammonium(1-A...)
Affinity DataEC50:  4.80E+3nMAssay Description:Agonistic activity evaluated in CHO(Chinese hamster ovary) cells expressing mGluR2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM66976(SMR001230688 | trans-( )-ACPD monohydrate | cid_16...)
Affinity DataEC50:  2.10E+3nMAssay Description:Agonistic activity evaluated in CHO(Chinese hamster ovary) cells expressing mGluR2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM17657(L-Glutamic acid | L-Glu | (2S)-2-aminopentanedioic...)
Affinity DataEC50:  610nMAssay Description:Agonistic activity evaluated in CHO(Chinese hamster ovary) cells expressing mGluR2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50079183(amino(3,5-dihydroxyphenyl)acetic acid | 3,5-DHPG |...)
Affinity DataEC50:  1.09E+4nMAssay Description:Compound was tested for ability to stimulate metabotropic glutamate receptor (mGluR) mediated phosphoinositide hydrolysis in rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2018
Entry Details

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50212347(CHEMBL74987)
Affinity DataEC50:  1.06E+5nMAssay Description:Compound was tested for ability to stimulate metabotropic glutamate receptor (mGluR) mediated phosphoinositide hydrolysis in rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2018
Entry Details

LigandPNGBDBM50056272((2S,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxy...)
Affinity DataEC50:  9.80nMAssay Description:Agonist activity at mGlu2/3 receptor in Sprague-Dawley rat forebrain assessed as inhibition of spontaneous Ca2+ oscillations in cortical neurons afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM393672(US9969726, Example 1 | US10597367, Example 1)
Affinity DataEC50:  330nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM393672(US9969726, Example 1 | US10597367, Example 1)
Affinity DataEC50:  480nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM393676(US9969726, Example 2 | US10597367, Example 2)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM393676(US9969726, Example 2 | US10597367, Example 2)
Affinity DataEC50: >1.00E+4nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM393680(US9969726, Example 3 | US10597367, Example 3)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM393680(US9969726, Example 3 | US10597367, Example 3)
Affinity DataEC50: >1.00E+4nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM393682(US9969726, Example 4 | US10597367, Example 4)
Affinity DataEC50:  2.26E+3nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM393682(US9969726, Example 4 | US10597367, Example 4)
Affinity DataEC50:  2.50E+3nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM393683(US9969726, Example 5 | US10597367, Example 5)
Affinity DataEC50:  1.35E+3nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM393683(US9969726, Example 5 | US10597367, Example 5)
Affinity DataEC50:  850nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM393684(US9969726, Example 6 | US10597367, Example 6)
Affinity DataEC50: >1.00E+4nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM393684(US9969726, Example 6 | US10597367, Example 6)
Affinity DataEC50: >1.00E+4nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM393685(US9969726, Example 7 | US10597367, Example 7)
Affinity DataEC50:  2.40E+3nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM393685(US9969726, Example 7 | US10597367, Example 7)
Affinity DataEC50: >1.00E+4nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM393691(US9969726, Example 8 | US10597367, Example 8)
Affinity DataEC50: >1.00E+4nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM393691(US9969726, Example 8 | US10597367, Example 8)
Affinity DataEC50:  1.92E+3nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM393698(US9969726, Example 9 | US10597367, Example 9)
Affinity DataEC50:  640nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM393698(US9969726, Example 9 | US10597367, Example 9)
Affinity DataEC50:  350nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM393699(US9969726, Example 10 | US10597367, Example 10)
Affinity DataEC50: >1.00E+4nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM393699(US9969726, Example 10 | US10597367, Example 10)
Affinity DataEC50: >1.00E+4nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM393700(US9969726, Example 11 | US10597367, Example 11)
Affinity DataEC50:  1.59E+3nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM393700(US9969726, Example 11 | US10597367, Example 11)
Affinity DataEC50:  3.40E+3nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM393703(US9969726, Example 12 | US10597367, Example 12)
Affinity DataEC50:  1.73E+3nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM393703(US9969726, Example 12 | US10597367, Example 12)
Affinity DataEC50:  2.14E+3nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM393715(US9969726, Example 13 | US10597367, Example 13)
Affinity DataEC50: >1.00E+4nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

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