Compile Data Set for Download or QSAR
Report error Found 723 for UniProtKB: P29702
LigandPNGBDBM50080742((S)-2-[(5-{[Benzyl-(5-fluoro-pyridin-3-yl)-amino]-...)
Affinity DataIC50: 0.100nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50080764((S)-2-({5-[(Benzyl-pyridin-3-yl-amino)-methyl]-2'-...)
Affinity DataIC50: 0.100nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50080765((S)-2-({5-[(Cyclohexylmethyl-pyridin-3-yl-amino)-m...)
Affinity DataIC50: 0.100nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM14453(1-({1-[(4-cyanophenyl)methyl]-1H-imidazol-5-yl}met...)
Affinity DataIC50: 0.150nMpH: 7.5 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase was determined by measuring the transfer of [3H]-FPP to substrate Ha-Ras-CVLS. The incorporated r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandPNGBDBM50127310(5-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of transfer of [3H]FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50112379(1-(3-Chloro-phenyl)-4-{2-[3-(2-methoxy-4'-trifluor...)
Affinity DataIC50: 0.170nMAssay Description:Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50127313(5-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50: 0.180nMAssay Description:Inhibition of transfer of [3H]FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50127321(5-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50: 0.180nMAssay Description:Inhibition of transfer of [3H]FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50112387(3-oxo-19-oxa-2,5,10,12-tetraazahexacyclo[18.6.2.22...)
Affinity DataIC50: 0.190nMAssay Description:Displacement of radiolabeled FTI from Farnesyltransferase in v-Ha-ras-transformed Rat1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50080748((S)-2-[(5-{[(3,5-Difluoro-benzyl)-thiazol-5-ylmeth...)
Affinity DataIC50: 0.200nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM13389(CHEMBL41748 | 4-{[(4-cyanophenyl)methoxy](1-methyl...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM13389(CHEMBL41748 | 4-{[(4-cyanophenyl)methoxy](1-methyl...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of [3H]FPP transfer to biotin K-ras peptide (KKSKTKCVIM) by bovine FTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50112387(3-oxo-19-oxa-2,5,10,12-tetraazahexacyclo[18.6.2.22...)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50083595(3-[3-((R)-2-Amino-3-mercapto-propylamino)-phenoxy]...)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of bovine Farnesyltransferase in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50127318(5-(3-Chloro-phenyl)-6-[(4-cyano-phenyl)-(3-methyl-...)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of transfer of [3H]FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50153786(4-((5-((4-cyanophenoxy)methyl)-1H-imidazol-1-yl)me...)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of bovine farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067566((S)-2-{[2'-Ethyl-5-(pyridin-3-yloxymethyl)-bipheny...)
Affinity DataIC50: 0.350nMAssay Description:In vitro inhibition of farnesyltransferase from bovine brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50153166(3''-Chloro-6-[3-(4-cyano-benzyl)-3H-imidazol-4-ylm...)
Affinity DataIC50: 0.370nMAssay Description:Inhibition of bovine farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50153802(3',4'-dichloro-6-(((1-(4-cyanobenzyl)-1H-imidazol-...)
Affinity DataIC50: 0.370nMAssay Description:Inhibition of bovine farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126336(4-{[(4-Cyano-3-naphthalen-1-yl-phenyl)-(3-methyl-3...)
Affinity DataIC50: 0.370nMAssay Description:In vitro inhibitory activity against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50153785(4-((1-(4-cyanobenzyl)-1H-imidazol-5-yl)methoxy)-2-...)
Affinity DataIC50: 0.380nMAssay Description:Inhibition of bovine farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126339(4-[(3-CYANO-BENZYL)-(3-METHYL-3H-IMIDAZOL-4-YLMETH...)
Affinity DataIC50: 0.390nMAssay Description:In vitro inhibitory activity against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50080743((S)-2-({5-[(Benzyl-thiazol-5-ylmethyl-amino)-methy...)
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50080747((S)-2-[(5-{[(3,5-Difluoro-benzyl)-phenyl-amino]-me...)
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067581((S)-2-{[2'-Methyl-5-(pyridin-3-ylaminomethyl)-biph...)
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50080750((S)-2-({5-[(Benzyl-pyrimidin-5-yl-amino)-methyl]-2...)
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067563((S)-2-{[2'-Methyl-5-(pyridin-3-yloxymethyl)-biphen...)
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067563((S)-2-{[2'-Methyl-5-(pyridin-3-yloxymethyl)-biphen...)
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibition of farnesyltransferase from bovine brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50083589(3-[4-((S)-2-Amino-3-mercapto-propylamino)-phenoxy]...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of bovine Farnesyltransferase in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50127306(5-[(5-Cyano-3'-trifluoromethoxy-biphenyl-2-ylmetho...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of transfer of [3H]FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067581((S)-2-{[2'-Methyl-5-(pyridin-3-ylaminomethyl)-biph...)
Affinity DataIC50: 0.420nMAssay Description:In vitro inhibition of farnesyltransferase from bovine brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50127315(A-315493 | 6-[(4-Cyano-3-naphthalen-1-yl-phenyl)-(...)
Affinity DataIC50: 0.430nMAssay Description:Inhibition of transfer of [3H]FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50153176(4''-tert-Butyl-6-[3-(4-cyano-benzyl)-3H-imidazol-4...)
Affinity DataIC50: 0.440nMAssay Description:Inhibition of bovine farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50083575(4-{5-[(4-Benzenesulfonyl-3-methyl-phenylamino)-met...)
Affinity DataIC50: 0.450nMAssay Description:Inhibition of bovine Farnesyltransferase in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126340(4-[(3-Cyano-benzyl)-(3-methyl-3H-imidazol-4-ylmeth...)
Affinity DataIC50: 0.450nMAssay Description:In vitro inhibitory activity against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50127324(5-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50: 0.450nMAssay Description:Inhibition of transfer of [3H]FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50112383(17-(5,5,5-trifluoropentyl)-19-oxa-2,5,10,12-tetraa...)
Affinity DataIC50: 0.480nMAssay Description:Displacement of radiolabeled FTI from Farnesyltransferase in v-Ha-ras-transformed Rat1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50153172(6-(((1-(4-cyanobenzyl)-1H-imidazol-5-yl)methoxy)me...)
Affinity DataIC50: 0.490nMAssay Description:Inhibition of bovine farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM14423(4-{[3-(3-ethoxyphenyl)-1-methyl-2-oxo-2,3-dihydro-...)
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase was determined by measuring the transfer of [3H]-FPP to substrate Ha-Ras-CVLS. The incorporated r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandPNGBDBM50080759((S)-2-{[2'-Methyl-4-phenethyl-5-(pyridin-3-yloxyme...)
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067559((S)-4-Methylsulfanyl-2-{[5-(pyridin-3-yloxymethyl)...)
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibition of farnesyltransferase from bovine brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50067584(2-{[5-((R)-2-Amino-3-mercapto-propylamino)-bipheny...)
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibition of farnesyltransferase from bovine brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50127311(5-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50: 0.510nMAssay Description:Inhibition of transfer of [3H]FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50127320(5'-(3-Chloro-phenyl)-6'-[(4-cyano-phenyl)-(3-methy...)
Affinity DataIC50: 0.510nMAssay Description:Inhibition of transfer of [3H]FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM17327((2S)-2-({1-[benzyl(1,3-thiazol-5-ylmethyl)carbamoy...)
Affinity DataIC50: 0.560nMpH: 7.5 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase was determined by measuring the transfer of [3H]-FPP to substrate Ha-Ras-CVLS. The incorporated r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2007
Entry Details Article
PubMed
LigandPNGBDBM50126335(R-115777 | 6-[(S)-AMINO(4-CHLOROPHENYL)(1-METHYL-1...)
Affinity DataIC50: 0.570nMAssay Description:In vitro inhibitory activity against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50127304(5-(3-Chloro-phenyl)-6-[(4-cyano-phenyl)-(3-methyl-...)
Affinity DataIC50: 0.570nMAssay Description:Inhibition of transfer of [3H]FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM14450(1-({1-[(4-cyanophenyl)methyl]-1H-imidazol-5-yl}met...)
Affinity DataIC50: 0.580nMpH: 7.5 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase was determined by measuring the transfer of [3H]-FPP to substrate Ha-Ras-CVLS. The incorporated r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandPNGBDBM50153776(5-((5-(((5-cyano-3'-ethoxybiphenyl-2-yl)methoxy)me...)
Affinity DataIC50: 0.580nMAssay Description:Inhibition of bovine farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50153782(6-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethoxymethy...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of bovine farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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