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Report error Found 39 of affinity data for UniProtKB/TrEMBL: P23919
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50550238(CHEMBL4749381)
Affinity DataIC50: 350nMAssay Description:Inhibition of GST-tagged human TMPK expressed in Escherichia coli BL21 incubated for 10 mins by luciferase-coupled TMPK assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50550239(CHEMBL4758532)
Affinity DataIC50: 470nMAssay Description:Inhibition of GST-tagged human TMPK expressed in Escherichia coli BL21 incubated for 10 mins by luciferase-coupled TMPK assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50365395(CHEMBL395814)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of human thymidylate kinase using dTMP as substrate after 30 mins by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50550240(CHEMBL4757635)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of GST-tagged human TMPK expressed in Escherichia coli BL21 incubated for 10 mins by luciferase-coupled TMPK assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50367702(CHEMBL606084)
Affinity DataIC50: 4.00E+3nMAssay Description:Concentration required to reduce Thymidylate kinase rate by 50% in human blast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50367696(CHEMBL605435)
Affinity DataIC50: 6.00E+3nMAssay Description:Concentration required to reduce Thymidylate kinase rate by 50% in human blast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50367698(CHEMBL604405)
Affinity DataIC50: 6.00E+3nMAssay Description:Concentration required to reduce Thymidylate kinase rate by 50% in human blast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50366828(CHEMBL1236157)
Affinity DataIC50: 8.00E+3nMAssay Description:Concentration required to reduce Thymidylate kinase rate by 50% in human blast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50398957(CHEMBL2179281)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human thymidylate kinase assessed as effect on ATP production by Escherichia coli DdlA and Malachite green reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50398958(CHEMBL2179279)
Affinity DataIC50: 4.34E+4nMAssay Description:Inhibition of human thymidylate kinase assessed as effect on ATP production by Escherichia coli DdlA and Malachite green reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50398959(CHEMBL2179277)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of human thymidylate kinase assessed as effect on ATP production by Escherichia coli DdlA and Malachite green reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50365393(CHEMBL1956669)
Affinity DataIC50: 1.23E+5nMAssay Description:Inhibition of human thymidylate kinase using dTMP as substrate after 30 mins by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50365394(CHEMBL1956676)
Affinity DataIC50: 1.24E+5nMAssay Description:Inhibition of human thymidylate kinase using dTMP as substrate after 30 mins by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50398961(CHEMBL2179269)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human thymidylate kinase assessed as effect on ATP production by Escherichia coli DdlA and Malachite green reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50398960(CHEMBL2179273)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human thymidylate kinase assessed as effect on ATP production by Escherichia coli DdlA and Malachite green reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50365392(CHEMBL1956668)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human thymidylate kinase using dTMP as substrate after 30 mins by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50365391(CHEMBL1956642)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human thymidylate kinase using dTMP as substrate after 30 mins by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50365390(CHEMBL1956634)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human thymidylate kinase using dTMP as substrate after 30 mins by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50398962(CHEMBL2179669)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human thymidylate kinase assessed as effect on ATP production by Escherichia coli DdlA and Malachite green reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50428613(CHEMBL2331747)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human thymidylate kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50367703(CHEMBL603793 | CHEMBL1794614)
Affinity DataIC50: 2.90E+5nMAssay Description:Concentration required to reduce Thymidylate kinase rate by 50% in human blast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50367697(CHEMBL606301)
Affinity DataIC50: 3.40E+5nMAssay Description:Concentration required to reduce Thymidylate kinase rate by 50% in human blast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50367704(CHEMBL604419)
Affinity DataIC50: 7.30E+5nMAssay Description:Concentration required to reduce Thymidylate kinase rate by 50% in human blast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50367699(CHEMBL604420)
Affinity DataIC50: 1.00E+6nMAssay Description:Concentration required to reduce Thymidylate kinase rate by 50% in human blast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50367701(CHEMBL605228)
Affinity DataIC50: 1.23E+6nMAssay Description:Concentration required to reduce Thymidylate kinase rate by 50% in human blast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50271535(6-(4-((5-bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H...)
Affinity DataKi:  9.20E+4nMAssay Description:Inhibition of human TMPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50359618(CHEMBL1928428)
Affinity DataKi:  9.50E+4nMAssay Description:Competitive inhibition of human TMPK by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50271531(5-(4-((5-chloro-2,4-dioxo-3,4-dihydropyrimidin-1(2...)
Affinity DataKi:  1.22E+5nMAssay Description:Inhibition of human TMPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM1(thymidine | dT)
Affinity DataKi:  1.80E+5nMAssay Description:Inhibition of human TMPK by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM1(thymidine | dT)
Affinity DataKi:  1.80E+5nMAssay Description:Inhibition of human TMPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50207303(5-bromo-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-...)
Affinity DataKi:  2.14E+5nMAssay Description:Inhibition of human TMPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50131909(1-(4-Aminomethyl-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataKi:  2.20E+5nMAssay Description:Inhibition of human TMPK by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50164421(4-[4-(5-Methyl-2,4-dioxo-3,4-dihydro-2H -pyrimidin...)
Affinity DataKi:  2.52E+5nMAssay Description:Inhibition of human TMPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50164412(4-(5-Bromo-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl...)
Affinity DataKi:  2.93E+5nMAssay Description:Inhibition of human TMPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50359622(CHEMBL1928432)
Affinity DataKi:  3.62E+5nMAssay Description:Inhibition of human TMPK assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50156570(1-[3-aminomethyl-3-deoxy-2-O-,6-N-(thiocarbonyl)-b...)
Affinity DataKi:  7.00E+5nMAssay Description:Inhibition of human TMPK by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50271448(5-[5-Chloro-4-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-...)
Affinity DataKi:  7.90E+5nMAssay Description:Inhibition of human TMPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50156573(1-(3-aminomethyl-2-O-,6-N-carbonyl-3-deoxy-beta-D-...)
Affinity DataKi:  1.10E+6nMAssay Description:Inhibition of human TMPK by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50156572(1-[3-C-(azido-methyl)-2,3-dideoxy-beta-D-thereo-pe...)
Affinity DataKi:  1.04E+6nMAssay Description:Inhibition of human TMPK by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed