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TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116766((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataKd:  1.60nMAssay Description:Binding affinity of compound against Dopamine receptor D2 was measured using [3H]pramipexole in Bovine striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM85099(SDZ SER 082 FUMARATE | CAS_141474-54-6 | SDZ SER-0...)
Affinity DataKd: <1.00E+4nMAssay Description:Binding affinity towards Dopamine receptor D2 of calf striatal tissue using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM85099(SDZ SER 082 FUMARATE | CAS_141474-54-6 | SDZ SER-0...)
Affinity DataKd: <1.00E+4nMAssay Description:Binding affinity towards Dopamine receptor D2 of calf striatal tissue using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50223644(CHEMBL366732)
Affinity DataIC50: 0.00140nMAssay Description:Compound was tested for its ability to displace [3H]spiroperidol from dopamine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50064578(6-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataIC50: 0.770nMAssay Description:Affinity towards Dopamine receptor D2 in membranes from bovine striatum using [3H]racloprideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50001955(APOKYN | CHEMBL53 | (Apomorphine) 6-Methyl-5,6,6a,...)
Affinity DataIC50: 1nMAssay Description:Tested for binding to dopamine receptor using [3H]apomorphine as radioligand in calf caudate nucleus homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2018
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 1.20nMAssay Description:Affinity towards Dopamine receptor D2 in membranes from bovine striatum using [3H]racloprideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of [3H]haloperidol binding to Dopamine receptor in calf caudate nuclei.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50224797(CHEMBL148829)
Affinity DataIC50: 2nMAssay Description:Binding affinity against dopamine receptor from P4 fractions of caudate nucleus (calf brain), using [3H]ADTN as the radioligand at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50224797(CHEMBL148829)
Affinity DataIC50: 2.5nMAssay Description:Binding affinity against dopamine receptor from P4 fractions of caudate nucleus (calf brain), using [3H]APO as the radioligand at a concentration of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2018
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50064576(7-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataIC50: 3nMAssay Description:Affinity towards Dopamine receptor D2 in membranes from bovine striatum using [3H]racloprideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50036855(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50: 3nMAssay Description:Binding affinity against D2 receptor in calf caudate nucleusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50007425(CHEMBL330274 | (S)-6-propyl-5,6,6a,7-tetrahydro-4H...)
Affinity DataIC50: 3.5nMAssay Description:Binding affinity against dopamine receptor from P4 fractions of caudate nucleus (calf brain), using [3H]ADTN as the radioligand at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataIC50: 3.70nMAssay Description:Tested for binding to dopamine receptor using [3H]- ADTN as radioligand in calf caudate nucleus homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50036851(8-[4-(Chroman-3-yl-propyl-amino)-butyl]-8-aza-spir...)
Affinity DataIC50: 4nMAssay Description:Binding affinity against D2 receptor in calf caudate nucleusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM29644(APOMORPHINE HYDROCHLORIDE | SMR000059235 | APOMORP...)
Affinity DataIC50: 4nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataIC50: 4.5nMAssay Description:Tested for binding to dopamine receptor using [3H]apomorphine as radioligand in calf caudate nucleus homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50001955(APOKYN | CHEMBL53 | (Apomorphine) 6-Methyl-5,6,6a,...)
Affinity DataIC50: 4.90nMAssay Description:Tested for binding to dopamine receptor using [3H]- ADTN as radioligand in calf caudate nucleus homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50001955(APOKYN | CHEMBL53 | (Apomorphine) 6-Methyl-5,6,6a,...)
Affinity DataIC50: 5nMAssay Description:Inhibition of [3H]dopamine binding to Dopamine receptor in calf caudate nuclei.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50007425(CHEMBL330274 | (S)-6-propyl-5,6,6a,7-tetrahydro-4H...)
Affinity DataIC50: 5nMAssay Description:Binding affinity against dopamine receptor from P4 fractions of caudate nucleus (calf brain), using [3H]APO as the radioligand at a concentration of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2018
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50064577(7-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataIC50: 5.20nMAssay Description:Affinity towards Dopamine receptor D2 in membranes from bovine striatum using [3H]racloprideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50064580(6-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}...)
Affinity DataIC50: 6nMAssay Description:Affinity towards Dopamine receptor D2 in membranes from bovine striatum using [3H]racloprideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM81195(cid_3153 | 6-Amino-5,6,7,8-tetrahydro-naphthalene-...)
Affinity DataIC50: 6nMAssay Description:Evaluated for the inhibition of binding of [3H]DA (dopamine) to dopamine receptor in calf striatal homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2018
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50064583(6-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}...)
Affinity DataIC50: 7nMAssay Description:Affinity towards Dopamine receptor D2 in membranes from bovine striatum using [3H]racloprideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50036874(4-Fluoro-N-{4-[(5-methoxy-chroman-3-yl)-propyl-ami...)
Affinity DataIC50: 7nMAssay Description:Binding affinity against D2 receptor in calf caudate nucleusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50064584(4-Methyl-7-{4-[4-(3-trifluoromethyl-phenyl)-pipera...)
Affinity DataIC50: 8nMAssay Description:Affinity towards Dopamine receptor D2 in membranes from bovine striatum using [3H]racloprideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50036850(8-{4-[(5-Hydroxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50: 8nMAssay Description:Binding affinity against D2 receptor in calf caudate nucleusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50016882(CHEMBL263574 | 1-Butyl-2,3,4,4a,10,10a-hexahydro-1...)
Affinity DataIC50: 8nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50001955(APOKYN | CHEMBL53 | (Apomorphine) 6-Methyl-5,6,6a,...)
Affinity DataIC50: 8.60nMAssay Description:Tested for binding to dopamine receptor using [3H]spiroperidol as radioligand in calf caudate nucleus homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50016888(CHEMBL162955 | 1-Propyl-2,3,4,4a,10,10a-hexahydro-...)
Affinity DataIC50: 9nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM82368(NSC_121851 | CAS_121851 | CHEMBL301060 | CHEMBL115...)
Affinity DataIC50: 10nMAssay Description:Binding affinity against D2 receptor in calf caudate nucleusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50064587(6-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataIC50: 10nMAssay Description:Affinity towards Dopamine receptor D2 in membranes from bovine striatum using [3H]racloprideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50064589(6-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataIC50: 10nMAssay Description:Affinity towards Dopamine receptor D2 in membranes from bovine striatum using [3H]racloprideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50036857(2-Methoxy-N-{4-[(5-methoxy-chroman-3-yl)-propyl-am...)
Affinity DataIC50: 10nMAssay Description:Binding affinity against D2 receptor in calf caudate nucleusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM82368(NSC_121851 | CAS_121851 | CHEMBL301060 | CHEMBL115...)
Affinity DataIC50: 10nMAssay Description:Binding affinity against D2 receptor in calf caudate nucleusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50010698((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Affinity DataIC50: 10nMAssay Description:Tested for binding to dopamine receptor using [3H]- ADTN as radioligand in calf caudate nucleus homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50228062(CHEMBL165290)
Affinity DataIC50: 11nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50010698((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Affinity DataIC50: 11nMAssay Description:Tested for binding to dopamine receptor using [3H]apomorphine as radioligand in calf caudate nucleus homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50001955(APOKYN | CHEMBL53 | (Apomorphine) 6-Methyl-5,6,6a,...)
Affinity DataIC50: 15nMAssay Description:In vitro inhibitory activity against dopamine receptor from calf caudate using [3H]dopamine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50001955(APOKYN | CHEMBL53 | (Apomorphine) 6-Methyl-5,6,6a,...)
Affinity DataIC50: 15nMAssay Description:In vitro inhibitory activity was evaluated against [3H]dopamine (DA) calf caudate dopamine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50016885(CHEMBL162282 | 1-Propyl-2,3,4,4a,10,10a-hexahydro-...)
Affinity DataIC50: 16nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50017543(9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10...)
Affinity DataIC50: 18nMAssay Description:In vitro inhibitory activity against dopamine receptor from calf caudate using [3H]dopamine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 19nMAssay Description:In vitro inhibitory activity was evaluated against,[3H]spiperone calf caudate (SPC) dopamine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 19nMAssay Description:In vitro inhibitory activity was evaluated against,[3H]spiperone calf caudate (SPC) dopamine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM82368(NSC_121851 | CAS_121851 | CHEMBL301060 | CHEMBL115...)
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]SDZ-205-501 from Dopamine receptor D2 in calf caudate nucleus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM82368(NSC_121851 | CAS_121851 | CHEMBL301060 | CHEMBL115...)
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]SDZ-205-501 from Dopamine receptor D2 in calf caudate nucleus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50017536(CHEMBL273786 | Flumezapine | 7-Fluoro-2-methyl-10-...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against dDopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50036846((5-Methoxy-chroman-3-yl)-(4-piperidin-1-yl-butyl)-...)
Affinity DataIC50: 20nMAssay Description:Binding affinity against D2 receptor in calf caudate nucleusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50036865(8-{3-[(5-Methoxy-chroman-3-yl)-propyl-amino]-propo...)
Affinity DataIC50: 20nMAssay Description:Binding affinity against D2 receptor in calf caudate nucleusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50228061(CHEMBL163167)
Affinity DataIC50: 20nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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