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TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643750(CHEMBL5575150)
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643763(CHEMBL5594712)
Affinity DataIC50: 0.700nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643748(CHEMBL5574671)
Affinity DataIC50: 0.700nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM524158(US11166942, Compound 60)
Affinity DataIC50: 1.5nMAssay Description:The ATF4 reporter was prepared by fusing the human full length 5′UTR of ATF4 (NCBI Accession No. BC022088.2) upstream of the firefly luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM524152(US11166942, Compound 54)
Affinity DataIC50: 1.60nMAssay Description:The ATF4 reporter was prepared by fusing the human full length 5′UTR of ATF4 (NCBI Accession No. BC022088.2) upstream of the firefly luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643768(CHEMBL5589825)
Affinity DataIC50: 1.90nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM524148(US11166942, Compound 50)
Affinity DataIC50: 1.93nMAssay Description:The ATF4 reporter was prepared by fusing the human full length 5′UTR of ATF4 (NCBI Accession No. BC022088.2) upstream of the firefly luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM524138(US11166942, Compound 31 | US11166942, Compound 47)
Affinity DataIC50: 1.98nMAssay Description:The ATF4 reporter was prepared by fusing the human full length 5′UTR of ATF4 (NCBI Accession No. BC022088.2) upstream of the firefly luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643749(CHEMBL5566312)
Affinity DataIC50: 2.30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643762(CHEMBL5591151)
Affinity DataIC50: 2.40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643770(CHEMBL5573122)
Affinity DataIC50: 2.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM524143(US11166942, Compound 45)
Affinity DataIC50: 2.60nMAssay Description:The ATF4 reporter was prepared by fusing the human full length 5′UTR of ATF4 (NCBI Accession No. BC022088.2) upstream of the firefly luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643744(CHEMBL4303573)
Affinity DataIC50: 2.70nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM524115(US11166942, Compound 4)
Affinity DataIC50: 3.10nMAssay Description:The ATF4 reporter was prepared by fusing the human full length 5′UTR of ATF4 (NCBI Accession No. BC022088.2) upstream of the firefly luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM524146(US11166942, Compound 48)
Affinity DataIC50: 3.36nMAssay Description:The ATF4 reporter was prepared by fusing the human full length 5′UTR of ATF4 (NCBI Accession No. BC022088.2) upstream of the firefly luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM524106(US11166942, Compound 1)
Affinity DataIC50: 3.60nMAssay Description:The ATF4 reporter was prepared by fusing the human full length 5′UTR of ATF4 (NCBI Accession No. BC022088.2) upstream of the firefly luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM524144(US11166942, Compound 46)
Affinity DataIC50: 3.60nMAssay Description:The ATF4 reporter was prepared by fusing the human full length 5′UTR of ATF4 (NCBI Accession No. BC022088.2) upstream of the firefly luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643780(CHEMBL5590478)
Affinity DataIC50: 3.80nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM524138(US11166942, Compound 31 | US11166942, Compound 47)
Affinity DataIC50: 4.16nMAssay Description:The ATF4 reporter was prepared by fusing the human full length 5′UTR of ATF4 (NCBI Accession No. BC022088.2) upstream of the firefly luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643758(CHEMBL5593424)
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643760(CHEMBL5572905)
Affinity DataIC50: 5.30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM524156(US11166942, Compound 58)
Affinity DataIC50: 5.70nMAssay Description:The ATF4 reporter was prepared by fusing the human full length 5′UTR of ATF4 (NCBI Accession No. BC022088.2) upstream of the firefly luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643759(CHEMBL5572011)
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643769(CHEMBL5567438)
Affinity DataIC50: 6.80nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643784(CHEMBL5565290)
Affinity DataIC50: 8.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643766(CHEMBL5573131)
Affinity DataIC50: 8.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643778(CHEMBL5571595)
Affinity DataIC50: 9.40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643771(Evetifator | DNL-343)
Affinity DataIC50: 9.80nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM524125(US11166942, Compound 14)
Affinity DataIC50: 10.2nMAssay Description:The ATF4 reporter was prepared by fusing the human full length 5′UTR of ATF4 (NCBI Accession No. BC022088.2) upstream of the firefly luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM524133(US11166942, Compound 22)
Affinity DataIC50: 10.3nMAssay Description:The ATF4 reporter was prepared by fusing the human full length 5′UTR of ATF4 (NCBI Accession No. BC022088.2) upstream of the firefly luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM524114(US11166942, Compound 3)
Affinity DataIC50: 10.6nMAssay Description:The ATF4 reporter was prepared by fusing the human full length 5′UTR of ATF4 (NCBI Accession No. BC022088.2) upstream of the firefly luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM524130(US11166942, Compound 19)
Affinity DataIC50: 11.5nMAssay Description:The ATF4 reporter was prepared by fusing the human full length 5′UTR of ATF4 (NCBI Accession No. BC022088.2) upstream of the firefly luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM524139(US11166942, Compound 32)
Affinity DataIC50: 12nMAssay Description:The ATF4 reporter was prepared by fusing the human full length 5′UTR of ATF4 (NCBI Accession No. BC022088.2) upstream of the firefly luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643767(CHEMBL5595443)
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643783(CHEMBL5569682)
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM524126(US11166942, Compound 15)
Affinity DataIC50: 12.4nMAssay Description:The ATF4 reporter was prepared by fusing the human full length 5′UTR of ATF4 (NCBI Accession No. BC022088.2) upstream of the firefly luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643772(CHEMBL5564968)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM524113(US11166942, Compound 2)
Affinity DataIC50: 18.4nMAssay Description:The ATF4 reporter was prepared by fusing the human full length 5′UTR of ATF4 (NCBI Accession No. BC022088.2) upstream of the firefly luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM524116(US11166942, Compound 5)
Affinity DataIC50: 18.8nMAssay Description:The ATF4 reporter was prepared by fusing the human full length 5′UTR of ATF4 (NCBI Accession No. BC022088.2) upstream of the firefly luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643765(CHEMBL5592433)
Affinity DataIC50: 19nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM524149(US11166942, Compound 51)
Affinity DataIC50: 19.8nMAssay Description:The ATF4 reporter was prepared by fusing the human full length 5′UTR of ATF4 (NCBI Accession No. BC022088.2) upstream of the firefly luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM524150(US11166942, Compound 52)
Affinity DataIC50: 26.9nMAssay Description:The ATF4 reporter was prepared by fusing the human full length 5′UTR of ATF4 (NCBI Accession No. BC022088.2) upstream of the firefly luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM524159(US11166942, Compound 61)
Affinity DataIC50: 29.4nMAssay Description:The ATF4 reporter was prepared by fusing the human full length 5′UTR of ATF4 (NCBI Accession No. BC022088.2) upstream of the firefly luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM524117(US11166942, Compound 6)
Affinity DataIC50: 30.8nMAssay Description:The ATF4 reporter was prepared by fusing the human full length 5′UTR of ATF4 (NCBI Accession No. BC022088.2) upstream of the firefly luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM524135(US11166942, Compound 24)
Affinity DataIC50: 32.2nMAssay Description:The ATF4 reporter was prepared by fusing the human full length 5′UTR of ATF4 (NCBI Accession No. BC022088.2) upstream of the firefly luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643752(CHEMBL5565662)
Affinity DataIC50: 34nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643757(CHEMBL5575064)
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643776(CHEMBL5574460)
Affinity DataIC50: 52nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM524134(US11166942, Compound 23)
Affinity DataIC50: 55.6nMAssay Description:The ATF4 reporter was prepared by fusing the human full length 5′UTR of ATF4 (NCBI Accession No. BC022088.2) upstream of the firefly luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643782(CHEMBL5570121)
Affinity DataIC50: 58nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
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