Compile Data Set for Download or QSAR
Report error Found 119 for UniProtKB: P15382
LigandPNGBDBM50121051(CHEMBL3621437)
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of human Kv7.1/KCNE1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
LigandPNGBDBM50099566(2-(4-Fluoro-phenyl)-2-(2-fluoro-phenyl)-2-phenyl-a...)
Affinity DataIC50: 9nMAssay Description:Selectivity for gardos channel; (Gardos channel vs 2000 nM for the cardiac IKs channel).)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
LigandPNGBDBM50106236((3R,4S)-Ethanesulfonic acid (6-benzyloxy-3-hydroxy...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50099582(N-[(3R,4S)-3-Hydroxy-2,2-dimethyl-6-(4,4,4-trifluo...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50099582(N-[(3R,4S)-3-Hydroxy-2,2-dimethyl-6-(4,4,4-trifluo...)
Affinity DataIC50: 120nMAssay Description:Inhibition of IKs currents in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
LigandPNGBDBM50106233(N-(6-Benzyloxy-3-hydroxy-2,2-dimethyl-chroman-4-yl...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50106231(N-[3-Hydroxy-2,2-dimethyl-6-(4,4,4-trifluoro-butox...)
Affinity DataIC50: 240nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50106232(N-(6-Butoxy-3-hydroxy-2,2-dimethyl-chroman-4-yl)-N...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50106237((3S,4R)-Ethanesulfonic acid (6-benzyloxy-3-hydroxy...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50106234((3S,4R)-(+)-N-[3-Hydroxy-2,2-dimethyl-6-(4,4,4-tri...)
Affinity DataIC50: 440nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50106228((3R,4S)-Ethanesulfonic acid (6-fluoro-3-hydroxy-2,...)
Affinity DataIC50: 700nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50235240(CHEMBL4065169)
Affinity DataIC50: 790nMAssay Description:Inhibition of human KCNQ1/KCNE1 expressed in HEK293 cells assessed as reduction in slowly activating delayed rectifier cardiac potassium current by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2019
Entry Details Article
PubMed
LigandPNGBDBM50106235(N-(3-Hydroxy-2,2-dimethyl-6-propoxy-chroman-4-yl)-...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50106226(N-(6-Chloro-3-hydroxy-2,2-dimethyl-chroman-4-yl)-N...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50106229(Ethanesulfonic acid (6-fluoro-3-hydroxy-2,2-dimeth...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50420077(CHEMBL2047511)
Affinity DataIC50: 1.30E+3nMAssay Description:Antagonist activity at KCNQ1/MINK expressed in CHO cells assessed as inhibition of KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50392995(CHEMBL2152523)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of IKs (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50420073(CHEMBL2047506)
Affinity DataIC50: 1.90E+3nMAssay Description:Antagonist activity at KCNQ1/MINK expressed in CHO cells assessed as inhibition of KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50099566(2-(4-Fluoro-phenyl)-2-(2-fluoro-phenyl)-2-phenyl-a...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Iks current KvLQT1 potassium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
LigandPNGBDBM50106223((3S,4R)-Ethanesulfonic acid (6-fluoro-3-hydroxy-2,...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50420057(CHEMBL2046674)
Affinity DataIC50: 2.90E+3nMAssay Description:Antagonist activity at KCNQ1/MINK expressed in CHO cells assessed as inhibition of KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50106224(Ethanesulfonic acid (3-hydroxy-2,2-dimethyl-chroma...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50420064(CHEMBL2046681)
Affinity DataIC50: 3.40E+3nMAssay Description:Antagonist activity at KCNQ1/MINK expressed in CHO cells assessed as inhibition of KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50420066(CHEMBL2046683)
Affinity DataIC50: 3.40E+3nMAssay Description:Antagonist activity at KCNQ1/MINK expressed in CHO cells assessed as inhibition of KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50106227((3R,4S)-Ethanesulfonic acid (6-cyano-3-hydroxy-2,2...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytes,(Experiment 1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50099567(Ethanesulfonic acid (6-cyano-3-hydroxy-2,2-dimethy...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytes,(Experiment 2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50420056(CHEMBL2046673)
Affinity DataIC50: 5.80E+3nMAssay Description:Antagonist activity at KCNQ1/MINK expressed in CHO cells assessed as inhibition of KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50420082(CHEMBL2047516)
Affinity DataIC50: 5.80E+3nMAssay Description:Antagonist activity at KCNQ1/MINK expressed in CHO cells assessed as inhibition of KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50106230(Ethanesulfonic acid (6-cyano-3-hydroxy-2,2-dimethy...)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50395464(CHEMBL2164048)
Affinity DataIC50: 8.12E+3nMAssay Description:Antagonist activity at KCNQ1/E1 expressed in CHO cells incubated for 3 mins by automated patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50343721(3-(4-(4-(2-fluoro-4-methylphenyl)-5-(4-methoxyphen...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of IKrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandPNGBDBM84745(DULOXETINE | LY-248686 | CAS_136434-34-9 | LY24868...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of slow delayed inward rectifying potassium current (Iks) in Chinese Hamster Ovary (CHO) cells expressing hKvLQT1/hminK measured using Ion...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
LigandPNGBDBM50343722(3-(4-(5-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-4-(2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IKrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandPNGBDBM50355405(CHEMBL1835153)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Iks channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50045833(CHEMBL3314349)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of human cardiac slowly activating delayed rectifier K+ channel expressed in CHO cells by electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
LigandPNGBDBM50420052(CHEMBL2046669)
Affinity DataIC50: 1.50E+4nMAssay Description:Antagonist activity at KCNQ1/MINK expressed in CHO cells assessed as inhibition of KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50420063(CHEMBL2046680)
Affinity DataIC50: 1.50E+4nMAssay Description:Antagonist activity at KCNQ1/MINK expressed in CHO cells assessed as inhibition of KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50468128(CHEMBL4282052)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of IKs (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM84735(CAS_99200-09-6 | NSC_71301 | Nebivolol)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of slow delayed inward rectifying potassium current (Iks) in Chinese Hamster Ovary (CHO) cells expressing hKvLQT1/hminK measured using Ion...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
LigandPNGBDBM50420061(CHEMBL2046678)
Affinity DataIC50: 1.70E+4nMAssay Description:Antagonist activity at KCNQ1/MINK expressed in CHO cells assessed as inhibition of KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50523763(CHEMBL4438854)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of IKs (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50109647(Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of slow delayed inward rectifying potassium current (Iks) in Chinese Hamster Ovary (CHO) cells expressing hKvLQT1/hminK measured using Ion...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
LigandPNGBDBM50385309(CHEMBL2035983)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Iks ion channel by voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50420070(CHEMBL2046684)
Affinity DataIC50: 2.20E+4nMAssay Description:Antagonist activity at KCNQ1/MINK expressed in CHO cells assessed as inhibition of KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50530637(CHEMBL4591417)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human KCNQ1/KCNE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50530637(CHEMBL4591417)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human KCNQ1/KCNE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM25351(N-[2-(4-{[(4-fluorophenyl)methyl]carbamoyl}-5-hydr...)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of slow delayed inward rectifying potassium current (Iks) in Chinese Hamster Ovary (CHO) cells expressing hKvLQT1/hminK measured using Ion...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
LigandPNGBDBM50103543(CHEMBL3358006)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of IKs channel (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
LigandPNGBDBM50420058(CHEMBL2046675)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at KCNQ1/MINK expressed in CHO cells assessed as inhibition of KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50246769(CHEMBL4064608)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of IKs (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2019
Entry Details Article
PubMed
Displayed 1 to 50 (of 119 total ) | Next | Last >>
Jump to: