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Report error Found 369 of affinity data for UniProtKB/TrEMBL: P14222
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50137357(CHEMBL3754633)
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant perforin (unknown origin) mediated lysis of human Jurkat cells pre-incubated for 30 mins with perforin followed by incubati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2017
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50361411(CHEMBL1934375)
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant perforin-mediated lysis of Jurkat cells assessed as [51Cr] release preincubated with perforin for 30 mins followed by incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50361417(CHEMBL1934381)
Affinity DataIC50: 360nMAssay Description:Inhibition of recombinant perforin-mediated lysis of Jurkat cells assessed as [51Cr] release preincubated with perforin for 30 mins followed by incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50361419(CHEMBL1934383)
Affinity DataIC50: 360nMAssay Description:Inhibition of recombinant perforin-mediated lysis of Jurkat cells assessed as [51Cr] release preincubated with perforin for 30 mins followed by incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50361406(CHEMBL1934370)
Affinity DataIC50: 370nMAssay Description:Inhibition of recombinant perforin-mediated lysis of Jurkat cells assessed as [51Cr] release preincubated with perforin for 30 mins followed by incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50361433(CHEMBL1934397)
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant perforin-mediated lysis of Jurkat cells assessed as [51Cr] release preincubated with perforin for 30 mins followed by incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50445263(CHEMBL3103651)
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant perforin (unknown origin)-mediated lysis of human [51Cr]-labelled Jurkat cells assessed as release of [51Cr] preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50361422(CHEMBL1934386)
Affinity DataIC50: 470nMAssay Description:Inhibition of recombinant perforin-mediated lysis of Jurkat cells assessed as [51Cr] release preincubated with perforin for 30 mins followed by incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50361416(CHEMBL1934380)
Affinity DataIC50: 490nMAssay Description:Inhibition of recombinant perforin-mediated lysis of Jurkat cells assessed as [51Cr] release preincubated with perforin for 30 mins followed by incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50361418(CHEMBL1934382)
Affinity DataIC50: 510nMAssay Description:Inhibition of recombinant perforin-mediated lysis of Jurkat cells assessed as [51Cr] release preincubated with perforin for 30 mins followed by incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50445286(CHEMBL3103907)
Affinity DataIC50: 510nMAssay Description:Inhibition of recombinant perforin (unknown origin)-mediated lysis of human [51Cr]-labelled Jurkat cells assessed as release of [51Cr] preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50445279(CHEMBL3103914)
Affinity DataIC50: 530nMAssay Description:Inhibition of recombinant perforin (unknown origin)-mediated lysis of human [51Cr]-labelled Jurkat cells assessed as release of [51Cr] preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50445276(CHEMBL3103917)
Affinity DataIC50: 550nMAssay Description:Inhibition of recombinant perforin (unknown origin)-mediated lysis of human [51Cr]-labelled Jurkat cells assessed as release of [51Cr] preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50445285(CHEMBL3103908)
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant perforin (unknown origin)-mediated lysis of human [51Cr]-labelled Jurkat cells assessed as release of [51Cr] preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50445259(CHEMBL3103655)
Affinity DataIC50: 630nMAssay Description:Inhibition of recombinant perforin (unknown origin)-mediated lysis of human [51Cr]-labelled Jurkat cells assessed as release of [51Cr] preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50445267(CHEMBL3103647)
Affinity DataIC50: 640nMAssay Description:Inhibition of recombinant perforin (unknown origin)-mediated lysis of human [51Cr]-labelled Jurkat cells assessed as release of [51Cr] preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50137379(CHEMBL3754407)
Affinity DataIC50: 670nMAssay Description:Inhibition of recombinant perforin (unknown origin) mediated lysis of human Jurkat cells pre-incubated for 30 mins with perforin followed by incubati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2017
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50276535(CHEMBL4169732)
Affinity DataIC50: 750nMAssay Description:Inhibition of perforin (unknown origin)-mediated 51Cr-labelled human Jurkat cell lysis preincubated with protein for 30 mins followed by cell additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2020
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50361400(CHEMBL1934364)
Affinity DataIC50: 780nMAssay Description:Inhibition of recombinant perforin-mediated lysis of Jurkat cells assessed as [51Cr] release preincubated with perforin for 30 mins followed by incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50445280(CHEMBL3103913)
Affinity DataIC50: 780nMAssay Description:Inhibition of recombinant perforin (unknown origin)-mediated lysis of human [51Cr]-labelled Jurkat cells assessed as release of [51Cr] preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50510947(CHEMBL4453871)
Affinity DataIC50: 780nMAssay Description:Inhibition of perforin (unknown origin) assessed as reduction in perforin-mediated cell lysis in human Jurkat T cells incubated for 30 mins by 51Cr r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50445303(CHEMBL3102870)
Affinity DataIC50: 790nMAssay Description:Inhibition of recombinant perforin (unknown origin)-mediated lysis of human [51Cr]-labelled Jurkat cells assessed as release of [51Cr] preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50361432(CHEMBL1934396)
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant perforin-mediated lysis of Jurkat cells assessed as [51Cr] release preincubated with perforin for 30 mins followed by incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50361420(CHEMBL1934384)
Affinity DataIC50: 820nMAssay Description:Inhibition of recombinant perforin-mediated lysis of Jurkat cells assessed as [51Cr] release preincubated with perforin for 30 mins followed by incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50137451(CHEMBL3753587)
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant perforin (unknown origin) mediated lysis of human Jurkat cells pre-incubated for 30 mins with perforin followed by incubati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2017
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50137456(CHEMBL3753271)
Affinity DataIC50: 920nMAssay Description:Inhibition of recombinant perforin (unknown origin) mediated lysis of human Jurkat cells pre-incubated for 30 mins with perforin followed by incubati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2017
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50445277(CHEMBL3103916)
Affinity DataIC50: 930nMAssay Description:Inhibition of recombinant perforin (unknown origin)-mediated lysis of human [51Cr]-labelled Jurkat cells assessed as release of [51Cr] preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50275059((Z)-1-(Benzo[b]thiophen-3-ylmethylene)-6-methyl-4-...)
Affinity DataIC50: 970nMAssay Description:Inhibition of recombinant perforin-mediated lysis of human Jurkat T cells by 51Cr release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50275059((Z)-1-(Benzo[b]thiophen-3-ylmethylene)-6-methyl-4-...)
Affinity DataIC50: 970nMAssay Description:Inhibition of recombinant perforin mediated lysis of human Jurkat cells pre-incubated for 30 mins with perforin followed by incubation with Jurkat ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50276462(CHEMBL4171638)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of perforin (unknown origin)-mediated 51Cr-labelled human Jurkat cell lysis preincubated with protein for 30 mins followed by cell additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2020
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50347203(CHEMBL1795754)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of recombinant perforin mediated lysis of human Jurkat cells pre-incubated for 30 mins with perforin followed by incubation with Jurkat ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50361401(CHEMBL1934365)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of recombinant perforin-mediated lysis of Jurkat cells assessed as [51Cr] release preincubated with perforin for 30 mins followed by incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50276547(CHEMBL4175880)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of perforin (unknown origin)-mediated 51Cr-labelled human Jurkat cell lysis preincubated with protein for 30 mins followed by cell additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2020
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50276597(CHEMBL4165670)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of perforin (unknown origin)-mediated 51Cr-labelled human Jurkat cell lysis preincubated with protein for 30 mins followed by cell additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2020
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50137455(CHEMBL3752189)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of recombinant perforin (unknown origin) mediated lysis of human Jurkat cells pre-incubated for 30 mins with perforin followed by incubati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2017
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50361431(CHEMBL1934395)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of recombinant perforin-mediated lysis of Jurkat cells assessed as [51Cr] release preincubated with perforin for 30 mins followed by incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50445268(CHEMBL3103646)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of recombinant perforin (unknown origin)-mediated lysis of human [51Cr]-labelled Jurkat cells assessed as release of [51Cr] preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50445307(CHEMBL3104019)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of recombinant perforin (unknown origin)-mediated lysis of human [51Cr]-labelled Jurkat cells assessed as release of [51Cr] preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50445281(CHEMBL3103912)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of recombinant perforin (unknown origin)-mediated lysis of human [51Cr]-labelled Jurkat cells assessed as release of [51Cr] preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50235190(CHEMBL4090472)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of recombinant perforin (unknown origin) assessed as decrease in lysis of 51Cr-labelled human Jurkat cells by measuring 51Cr release prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2019
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50235190(CHEMBL4090472)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of recombinant Perforin-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50445283(CHEMBL3103910)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of recombinant perforin (unknown origin)-mediated lysis of human [51Cr]-labelled Jurkat cells assessed as release of [51Cr] preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50361429(CHEMBL1934393)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of recombinant perforin-mediated lysis of Jurkat cells assessed as [51Cr] release preincubated with perforin for 30 mins followed by incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50137447(CHEMBL3752776)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant perforin (unknown origin) mediated lysis of human Jurkat cells pre-incubated for 30 mins with perforin followed by incubati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2017
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50276426(CHEMBL4162248)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of perforin (unknown origin)-mediated 51Cr-labelled human Jurkat cell lysis preincubated with protein for 30 mins followed by cell additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2020
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50445278(CHEMBL3103915)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of recombinant perforin (unknown origin)-mediated lysis of human [51Cr]-labelled Jurkat cells assessed as release of [51Cr] preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50275013((Z)-1-((1H-Indol-2-yl)methylene)-6-methyl-4-thioxo...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant perforin-mediated lysis of human Jurkat T cells by 51Cr release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50361412(CHEMBL1934376)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant perforin-mediated lysis of Jurkat cells assessed as [51Cr] release preincubated with perforin for 30 mins followed by incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50276521(CHEMBL4159529)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of perforin (unknown origin)-mediated 51Cr-labelled human Jurkat cell lysis preincubated with protein for 30 mins followed by cell additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2020
Entry Details Article
PubMed
TargetPerforin-1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50445270(CHEMBL3103644)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of recombinant perforin (unknown origin)-mediated lysis of human [51Cr]-labelled Jurkat cells assessed as release of [51Cr] preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
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