Compile Data Set for Download or QSAR
Report error Found 42 of affinity data for UniProtKB/TrEMBL: P0AD64
TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50149467((5R,6Z)-6-(6,7-dihydro-5H-cyclopenta-[d]imidazo[2,...)
Affinity DataIC50: 12nMAssay Description:Inhibition of Escherichia coli SHV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212641(Brobactam)
Affinity DataIC50: 17.8nMAssay Description:Inhibitory activity against Escherichia coli HA208 Class-III SHV-1 type beta-lactamase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details

TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50021959(antibiotic MM 14151 | CHEMBL777 | MM 14151 | clavu...)
Affinity DataIC50: 20.1nMAssay Description:Inhibitory activity against Escherichia coli HA208 Class-III SHV-1 type beta-lactamase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details

TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212645(CHEMBL305908)
Affinity DataIC50: 26.4nMAssay Description:Inhibitory activity against Escherichia coli HA208 Class-III SHV-1 type beta-lactamase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details

TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50021959(antibiotic MM 14151 | CHEMBL777 | MM 14151 | clavu...)
Affinity DataIC50: 28nMAssay Description:Inhibition of Escherichia coli SHV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212644(CHEMBL73450)
Affinity DataIC50: 51nMAssay Description:Inhibitory activity against Escherichia coli HA208 Class-III SHV-1 type beta-lactamase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details

TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212638(CHEMBL302512)
Affinity DataIC50: 72nMAssay Description:Inhibitory activity against Escherichia coli HA208 Class-III SHV-1 type beta-lactamase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details

TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212634(CHEMBL309009)
Affinity DataIC50: 104nMAssay Description:Inhibitory activity against Escherichia coli HA208 Class-III SHV-1 type beta-lactamase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details

TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50: 110nMAssay Description:Inhibition of Klebsiella pneumoniae Beta-Lactamase SHV-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50: 133nMAssay Description:Inhibitory activity against Escherichia coli HA208 Class-III SHV-1 type beta-lactamase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details

TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212643(CHEMBL308516)
Affinity DataIC50: 141nMAssay Description:Inhibitory activity against Escherichia coli HA208 Class-III SHV-1 type beta-lactamase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details

TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212642(CHEMBL70269)
Affinity DataIC50: 146nMAssay Description:Inhibitory activity against Escherichia coli HA208 Class-III SHV-1 type beta-lactamase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details

TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50218934(sodium (8S,9R)-10(E)-ethylidene-4(S)-(2'-fluoroeth...)
Affinity DataIC50: 148nMAssay Description:Inhibition of Escherichia coli SHV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50218935(sodium (8S,9R)-10(E)-ethylidene-4(S)-methoxy-11-ox...)
Affinity DataIC50: 151nMAssay Description:Inhibition of Escherichia coli SHV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50218936(sodium (8S,9R)-10(E)-ethylidene-4(S)-(2'-cyanoetho...)
Affinity DataIC50: 152nMAssay Description:Inhibition of Escherichia coli SHV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50021959(antibiotic MM 14151 | CHEMBL777 | MM 14151 | clavu...)
Affinity DataIC50: 170nMAssay Description:Inhibition of Klebsiella pneumoniae Beta-Lactamase SHV-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50021959(antibiotic MM 14151 | CHEMBL777 | MM 14151 | clavu...)
Affinity DataIC50: 170nMAssay Description:Inhibition of Klebsiella pneumoniae Beta-Lactamase SHV-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50218939(sodium (5S,8aS,8bR)-5-butoxy-1-eth-(E)-ylidene-2-o...)
Affinity DataIC50: 206nMAssay Description:Inhibition of Escherichia coli SHV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50218932(sodium (8R,9R)-10(S)-[1(R)-hydroxyethyl]-4(R)-buto...)
Affinity DataIC50: 219nMAssay Description:Inhibition of Escherichia coli SHV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50: 222nMAssay Description:Inhibition of Escherichia coli SHV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50218933(sodium (8R,9R)-10(E)-ethylidene-4(R)-ethoxy-11-oxo...)
Affinity DataIC50: 284nMAssay Description:Inhibition of Escherichia coli SHV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50218938(sodium (8S,9R)-10(E)-ethylidene-4(S)-isopropoxy-11...)
Affinity DataIC50: 340nMAssay Description:Inhibition of Escherichia coli SHV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212637(CHEMBL72046)
Affinity DataIC50: 370nMAssay Description:Inhibitory activity against Escherichia coli HA208 Class-III SHV-1 type beta-lactamase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details

TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50218937(sodium (8S,9R)-10(E)-ethylidene-4(S)-ethoxy-11-oxo...)
Affinity DataIC50: 385nMAssay Description:Inhibition of Escherichia coli SHV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212636(CHEMBL310221)
Affinity DataIC50: 503nMAssay Description:Inhibitory activity against Escherichia coli HA208 Class-III SHV-1 type beta-lactamase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details

TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50076680(Sodium; (2S,3R,5R)-3-((Z)-2-cyano-vinyl)-3-methyl-...)
Affinity DataIC50: 540nMAssay Description:Compound was tested for inhibition of Beta-lactamase from SHV-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212640(CHEMBL423309)
Affinity DataIC50: 577nMAssay Description:Inhibitory activity against Escherichia coli HA208 Class-III SHV-1 type beta-lactamase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details

TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212646(CHEMBL72972)
Affinity DataIC50: 655nMAssay Description:Inhibitory activity against Escherichia coli HA208 Class-III SHV-1 type beta-lactamase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details

TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212639(CHEMBL302241)
Affinity DataIC50: 926nMAssay Description:Inhibitory activity against Escherichia coli HA208 Class-III SHV-1 type beta-lactamase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details

TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212635(CHEMBL415266)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibitory activity against Escherichia coli HA208 Class-III SHV-1 type beta-lactamase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details

TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50021954(UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...)
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibitory activity against Escherichia coli HA208 Class-III SHV-1 type beta-lactamase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details
PDB3D3D Structure (crystal)
TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataKi:  220nM IC50: 30nMpH: 7.4Assay Description:Steady state kinetics were performed on an Agilent 8453 diode array spectrophotometer in 10 mM phosphate-buffered saline (pH 7.4). IC50, defined as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2015
Entry Details Article
PubMed
TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM152696(PSR-3-283A)
Affinity DataKi:  560nM IC50: 320nMpH: 7.4Assay Description:Steady state kinetics were performed on an Agilent 8453 diode array spectrophotometer in 10 mM phosphate-buffered saline (pH 7.4). IC50, defined as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2015
Entry Details Article
PubMed
TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50021954(UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...)
Affinity DataKi:  1.50E+3nM IC50: 3.40E+3nMpH: 7.4Assay Description:Steady state kinetics were performed on an Agilent 8453 diode array spectrophotometer in 10 mM phosphate-buffered saline (pH 7.4). IC50, defined as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50021959(antibiotic MM 14151 | CHEMBL777 | MM 14151 | clavu...)
Affinity DataKi:  2.00E+3nM IC50: 100nMpH: 7.4Assay Description:Steady state kinetics were performed on an Agilent 8453 diode array spectrophotometer in 10 mM phosphate-buffered saline (pH 7.4). IC50, defined as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2015
Entry Details Article
PubMed
TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50370963(CEFTAZIDIME BATSI)
Affinity DataKi:  2.20E+3nMAssay Description:Binding affinity at Beta-lactamase SHV1 expressed in Escherichia coli DH10B cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50486725(CHEMBL2236666)
Affinity DataKi:  4.23E+3nMAssay Description:Inhibition of Klebsiella pneumoniae beta-lactamase SHV-89More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202234((Z)-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)aceta...)
Affinity DataKi:  8.90E+3nMAssay Description:Binding affinity at Beta-lactamase SHV1 expressed in Escherichia coli DH10B cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50486723(PENEM-2)
Affinity DataKi:  6.79E+4nMAssay Description:Inhibition of Klebsiella pneumoniae beta-lactamase SHV-89More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50486724(PENEM-1)
Affinity DataKi:  1.10E+5nMAssay Description:Inhibition of Klebsiella pneumoniae beta-lactamase SHV-89More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50021959(antibiotic MM 14151 | CHEMBL777 | MM 14151 | clavu...)
Affinity DataKi:  2.29E+5nMAssay Description:Inhibition of Klebsiella pneumoniae beta-lactamase SHV-89More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetBeta-lactamase SHV-1(Pseudomonas aeruginosa (g-Proteobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202233(Acylglycineboronic acid, 5 | CHEMBL227673 | acetam...)
Affinity DataKi:  3.00E+5nMAssay Description:Binding affinity at Beta-lactamase SHV1 expressed in Escherichia coli DH10B cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed