Compile Data Set for Download or QSAR
Report error Found 1820 of affinity data for UniProtKB/TrEMBL: P09960
TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303649(4-{(S)-2-[4-(4-Chlorophenoxy)phenoxymethyl]pyrroli...)
Affinity DataKd:  25nMAssay Description:Binding affinity to human recombinant LTA4H by isothermal calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50197084(CHEMBL3883608)
Affinity DataKd:  220nMAssay Description:Binding affinity to human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H at 35 degC by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50197084(CHEMBL3883608)
Affinity DataKd:  130nMAssay Description:Binding affinity to human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H at 15 degC by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50197085(CHEMBL3921982)
Affinity DataKd:  60nMAssay Description:Binding affinity to human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H at 15 degC by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataKd:  6.25E+3nMAssay Description:Binding affinity to human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H at 25 degC by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50116538(SC-57461A | CHEMBL543405 | CHEMBL112671 | 3-{[3-(4...)
Affinity DataKd:  350nMAssay Description:Binding affinity to human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H at 35 degC by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50197085(CHEMBL3921982)
Affinity DataKd:  270nMAssay Description:Binding affinity to human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H at 35 degC by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50116538(SC-57461A | CHEMBL543405 | CHEMBL112671 | 3-{[3-(4...)
Affinity DataKd:  60nMAssay Description:Binding affinity to human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H at 15 degC by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataKd:  6.37E+3nMAssay Description:Binding affinity to human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H at 15 degC by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50197084(CHEMBL3883608)
Affinity DataKd:  310nMAssay Description:Binding affinity to human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H at 25 degC by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM23971(CHEMBL29292 | (2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-...)
Affinity DataKd:  5.15E+3nMAssay Description:Binding affinity to human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H at 35 degC by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataKd:  8.47E+3nMAssay Description:Binding affinity to human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H at 35 degC by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50197085(CHEMBL3921982)
Affinity DataKd:  270nMAssay Description:Binding affinity to human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H at 25 degC by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM23971(CHEMBL29292 | (2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-...)
Affinity DataKd:  4.63E+3nMAssay Description:Binding affinity to human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H at 15 degC by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM23971(CHEMBL29292 | (2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-...)
Affinity DataKd:  2.05E+3nMAssay Description:Binding affinity to human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H at 25 degC by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50116538(SC-57461A | CHEMBL543405 | CHEMBL112671 | 3-{[3-(4...)
Affinity DataKd:  290nMAssay Description:Binding affinity to human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H at 25 degC by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM326921(4-(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2- yl...)
Affinity DataIC50: 0.0420nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM326921(4-(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2- yl...)
Affinity DataIC50: 0.0420nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM326945(1-(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]py...)
Affinity DataIC50: 0.0700nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM326945(1-(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]py...)
Affinity DataIC50: 0.0700nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM327137(4-(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]py...)
Affinity DataIC50: 0.0800nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM327137(4-(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]py...)
Affinity DataIC50: 0.0800nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM327181(1-{(1S,4S)-5-[(S)-4-(2,3-Dihydro- [1,4]dioxino[2,...)
Affinity DataIC50: 0.0900nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM327189(5-[(S)-4-(2,3-Dihydro- [1,4]dioxino[2,3-b]pyridin...)
Affinity DataIC50: 0.0900nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM326957(N-(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]py...)
Affinity DataIC50: 0.0900nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM327016((3S)-3-{4-[(1s,4s)-7- azabicyclo[2.2.1]hept-7- y...)
Affinity DataIC50: 0.0900nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM327016((3S)-3-{4-[(1s,4s)-7- azabicyclo[2.2.1]hept-7- y...)
Affinity DataIC50: 0.0900nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM326957(N-(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]py...)
Affinity DataIC50: 0.0900nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM327151(7-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2-yl]benz...)
Affinity DataIC50: 0.100nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM326947(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2-yl]benz...)
Affinity DataIC50: 0.100nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM326992((3S)-3-[4-(azepan-1- ylmethyl)phenyl]-2,3- dihyd...)
Affinity DataIC50: 0.100nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM327040(4-(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]py...)
Affinity DataIC50: 0.100nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM326947(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2-yl]benz...)
Affinity DataIC50: 0.100nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM327151(7-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2-yl]benz...)
Affinity DataIC50: 0.100nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM326992((3S)-3-[4-(azepan-1- ylmethyl)phenyl]-2,3- dihyd...)
Affinity DataIC50: 0.100nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM327040(4-(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]py...)
Affinity DataIC50: 0.100nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM327185((1S,4S)-5-[(S)-4-(2,3-Dihydro- [1,4]dioxino[2,3-b...)
Affinity DataIC50: 0.110nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM326933([(3R)-1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2- ...)
Affinity DataIC50: 0.110nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM326933([(3R)-1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2- ...)
Affinity DataIC50: 0.110nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM327156((1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2- yl]b...)
Affinity DataIC50: 0.120nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM326944(7-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyrid...)
Affinity DataIC50: 0.120nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM326997(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2- yl]be...)
Affinity DataIC50: 0.120nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
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TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50575488(CHEMBL4852381)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM326997(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2- yl]be...)
Affinity DataIC50: 0.120nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM326944(7-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyrid...)
Affinity DataIC50: 0.120nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM327156((1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2- yl]b...)
Affinity DataIC50: 0.120nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM327061(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2-yl]benz...)
Affinity DataIC50: 0.130nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM327068((3S)-3-{4-[(3-methoxypiperidin- 1-yl)methyl]phenyl...)
Affinity DataIC50: 0.130nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM327093(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2-yl]benz...)
Affinity DataIC50: 0.130nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM327096(8-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyridin...)
Affinity DataIC50: 0.130nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent

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