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Report error Found 13 for UniProtKB: P08519
TargetApolipoprotein(a)(Human)
Eli Lilly

US Patent
LigandPNGBDBM544449((2S)-3-[3-[[Bis[[3-[(2S)-2-carboxy-2-[(3R)-pyrroli...)
Affinity DataIC50: 0.314nMAssay Description:The in vitro binding affinity of compounds to the intended target human Apo(a) protein is tested in a competitive binding assay. Human Apo(a) protein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
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TargetApolipoprotein(a)(Human)
Eli Lilly

US Patent
LigandPNGBDBM544455(3-[3-[[bis[[3-[2-carboxy-2-[(3R)-pyrrolidin-3-yl]p...)
Affinity DataIC50: 0.314nMAssay Description:The in vitro binding affinity of compounds to the intended target human Apo(a) protein is tested in a competitive binding assay. Human Apo(a) protein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
Go to US Patent

TargetApolipoprotein(a)(Human)
Eli Lilly

US Patent
LigandPNGBDBM544456((2S)-3-[3-[3-[(2S)-2-Carboxy-2-[(3R)-pyrrolidin-3-...)
Affinity DataIC50: 0.314nMAssay Description:The in vitro binding affinity of compounds to the intended target human Apo(a) protein is tested in a competitive binding assay. Human Apo(a) protein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
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TargetLipoprotein(a) /B receptor(Human)
Tuojie Biotech (Shanghai) Co.

US Patent
LigandPNGBDBM717809(US20250042847, Compound 6)
Affinity DataIC50: 0.410nMAssay Description:Experimental steps: Equal amounts of Apo(a) and ApoB serum were mixed with a serially diluted test compound (highest concentration at 100 nM, seriall...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/11/2025
Entry Details
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TargetLipoprotein(a) /B receptor(Human)
Tuojie Biotech (Shanghai) Co.

US Patent
LigandPNGBDBM717800(US20250042847, Compound 1)
Affinity DataIC50: 0.75nMAssay Description:Experimental steps: Equal amounts of Apo(a) and ApoB serum were mixed with a serially diluted test compound (highest concentration at 100 nM, seriall...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/11/2025
Entry Details
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TargetLipoprotein(a) /B receptor(Human)
Tuojie Biotech (Shanghai) Co.

US Patent
LigandPNGBDBM717810(US20250042847, Compound 7)
Affinity DataIC50: 0.760nMAssay Description:Experimental steps: Equal amounts of Apo(a) and ApoB serum were mixed with a serially diluted test compound (highest concentration at 100 nM, seriall...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/11/2025
Entry Details
Go to US Patent

TargetLipoprotein(a) /B receptor(Human)
Tuojie Biotech (Shanghai) Co.

US Patent
LigandPNGBDBM717808(US20250042847, Compound 5)
Affinity DataIC50: 0.780nMAssay Description:Experimental steps: Equal amounts of Apo(a) and ApoB serum were mixed with a serially diluted test compound (highest concentration at 100 nM, seriall...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/11/2025
Entry Details
Go to US Patent

TargetLipoprotein(a) /B receptor(Human)
Tuojie Biotech (Shanghai) Co.

US Patent
LigandPNGBDBM717807(US20250042847, Compound 4)
Affinity DataIC50: 0.850nMAssay Description:Experimental steps: Equal amounts of Apo(a) and ApoB serum were mixed with a serially diluted test compound (highest concentration at 100 nM, seriall...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/11/2025
Entry Details
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TargetLipoprotein(a) /B receptor(Human)
Tuojie Biotech (Shanghai) Co.

US Patent
LigandPNGBDBM717806(US20250042847, Compound 3)
Affinity DataIC50: 1.40nMAssay Description:Experimental steps: Equal amounts of Apo(a) and ApoB serum were mixed with a serially diluted test compound (highest concentration at 100 nM, seriall...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/11/2025
Entry Details
Go to US Patent

TargetLipoprotein(a) /B receptor(Human)
Tuojie Biotech (Shanghai) Co.

US Patent
LigandPNGBDBM717805(US20250042847, Compound 2)
Affinity DataIC50: 1.70nMAssay Description:Experimental steps: Equal amounts of Apo(a) and ApoB serum were mixed with a serially diluted test compound (highest concentration at 100 nM, seriall...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/11/2025
Entry Details
Go to US Patent

TargetApolipoprotein(a)(Human)
Eli Lilly

US Patent
LigandPNGBDBM544454((2S)-3-[3-[[[3-[(2S)-2-Carboxy-2-[(3R)-pyrrolidin-...)
Affinity DataIC50: 2.13nMAssay Description:The in vitro binding affinity of compounds to the intended target human Apo(a) protein is tested in a competitive binding assay. Human Apo(a) protein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
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TargetApolipoprotein(a)(Human)
Eli Lilly

US Patent
LigandPNGBDBM544458((2R)-3-Phenyl-2-[(3S)-pyrrolidin-3-yl]propanoic ac...)
Affinity DataIC50: 126nMAssay Description:The in vitro binding affinity of compounds to the intended target human Apo(a) protein is tested in a competitive binding assay. Human Apo(a) protein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
Go to US Patent

TargetApolipoprotein(a)(Human)
Eli Lilly

US Patent
LigandPNGBDBM544457((2S)-3-Phenyl-2-[(3R)-pyrrolidin-3-yl]propanoic ac...)
Affinity DataIC50: 152nMAssay Description:The in vitro binding affinity of compounds to the intended target human Apo(a) protein is tested in a competitive binding assay. Human Apo(a) protein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)