Compile Data Set for Download or QSAR
Report error Found 140 of affinity data for UniProtKB/TrEMBL: P07688
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16511((2S)-1-[(2S)-2-{[(2S,3S)-3-{[(1S)-1-({[(2-methoxy-...)
Affinity DatapH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16499(CA inhibitor 2 | EtO-tES-Ile-Ala-OH | CA075 | (2S)...)
Affinity DataIC50: 23nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16500(CA inhibitor 3 | EtO-tES-Ile-Ile-OH | (2S)-2-[(2S,...)
Affinity DataIC50: 24nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16502(BzlNH-tES-Ile-Pro-OH | CA inhibitor 5 | N-{[(2S,3S...)
Affinity DataIC50: 29nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16509(CA074 | CHEMBL490920 | (2S)-1-[(2S,3S)-3-methyl-2-...)
Affinity DataIC50: 38nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16510(HO-tES-Leu-NH-CH2-CH2CH(CH3)2 | (2S,3S)-3-[[(2S)-4...)
Affinity DataIC50: 40nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50046899(2-Acetylamino-4-methyl-pentanoic acid [1-(5-amino-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16508((2S)-1-[(2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxir...)
Affinity DataIC50: 120nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50286441(Ac-LLR-CHO | Ac-Leu-Leu-Arg-H | (S)-2-((S)-2-Acety...)
Affinity DataIC50: 310nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16501(EtO-tES-Thr-Ile-OH | (2S)-2-[(2S,3R)-2-{[(2S,3S)-3...)
Affinity DataIC50: 410nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50046896(2-Acetylamino-4-methyl-pentanoic acid [1-(1-formyl...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50046887(2-(2-Acetylamino-3-phenyl-propionylamino)-4-methyl...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50046888(2-(2-Acetylamino-3-methyl-butyrylamino)-4-methyl-p...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50484453(Shishicrellastatin A)
Affinity DataIC50: 6.79E+3nMAssay Description:Inhibition of bovine cathepsin B after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50484452(Shishicrellastatin B)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of bovine cathepsin B after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16504(benzyl (2S)-1-[(2S,3S)-3-methyl-2-{[(2S,3S)-3-(pro...)
Affinity DataIC50: 9.10E+3nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50047352(CHEMBL3314610)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of bovine spleen cathepsin B using Z-Arg-Arg-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50046885(2-(2-Acetylamino-3-phenyl-propionylamino)-N-(1-for...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50046890(2-Acetylamino-4-methyl-pentanoic acid [1-(5-amino-...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50047353(CHEMBL3314607)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of bovine spleen cathepsin B using Z-Arg-Arg-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16506(CA inhibitor 9 | (2S)-1-(2-{[(2S,3S)-3-(ethoxycarb...)
Affinity DataIC50: 1.53E+4nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50368642(ACETYLPEPSTATIN)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of bovine spleen cathepsin B using Z-Arg-Arg-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50046891(2-(2-Acetylamino-4-methyl-pentanoylamino)-3-methyl...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50046898(2-Acetylamino-4-methyl-pentanoic acid [1-(5-amino-...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50046900(2-(2-Acetylamino-3-phenyl-propionylamino)-4-methyl...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16497((2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxiran-2-yl]...)
Affinity DataIC50: 2.40E+4nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50047355(CHEMBL3314608)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of bovine spleen cathepsin B using Z-Arg-Arg-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50047354(CHEMBL3314609)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of bovine spleen cathepsin B using Z-Arg-Arg-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50046895(2-Acetylamino-3-methyl-pentanoic acid [1-(5-amino-...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50047351(CHEBI:7988 | CHEMBL3314611)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of bovine spleen cathepsin B using Z-Arg-Arg-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16505(BzlNH-tES-Ile-Pro-OBzl | benzyl N-{[(2S,3S)-3-(ben...)
Affinity DataIC50: 4.60E+4nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50046894(2-(2-Acetylamino-3-methyl-butyrylamino)-4-methyl-p...)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50046892(2-Acetylamino-4-methyl-pentanoic acid [1-(1-formyl...)
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16503(CA074Me | CA inhibitor 6 | methyl N-{[(2S,3S)-3-(p...)
Affinity DataIC50: 6.80E+4nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2007
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50046893(2-[2-Acetylamino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50: 7.80E+4nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50046889(2-Acetylamino-4-methyl-pentanoic acid [1-(1-formyl...)
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50147766(CHEMBL3765121)
Affinity DataIC50: 1.70E+5nMAssay Description:Inhibition of bovine spleen cathepsin B using Z-Arg-Arg-MCA as substrate incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50224807(cyclo(Pro-Gly-Leu-Val-Met-Phe-Gly-Val) | CHEMBL400...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of bovine Cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50147767(CHEMBL3765089)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of bovine spleen cathepsin B using Z-Arg-Arg-MCA as substrate incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50053851((3-Methyl-1-{1-[3-(3,4,4a,8a-tetrahydro-2H-quinoli...)
Affinity DataKi:  0.0940nMAssay Description:Inhibition of bovine cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50053800((1-{1-Benzyl-2-oxo-2-[3-(3,4,4a,8a-tetrahydro-2H-q...)
Affinity DataKi:  0.140nMAssay Description:Inhibition of bovine cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50053847((1-{1-[2-(1H-Indol-3-yl)-ethylaminooxalyl]-propylc...)
Affinity DataKi:  31nMAssay Description:Inhibition of bovine cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50090645((S)-2-Benzyl-N-[(S)-4-guanidino-1-(2-oxo-acetyl)-b...)
Affinity DataKi:  40nMAssay Description:Ability to block cathepsin B-catalyzed hydrolysis of the fluorogenic substrate Z-Arg-Arg-NHMecMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50053833({1-[1-(2-Hydroxy-2-naphthalen-1-yl-ethylaminooxaly...)
Affinity DataKi:  63nMAssay Description:Inhibition of bovine cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50053798({1-[1-(2-Hydroxy-2-naphthalen-2-yl-ethylaminooxaly...)
Affinity DataKi:  63nMAssay Description:Inhibition of bovine cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50053820((1-{1-[2-(4-Dimethylamino-phenyl)-2-hydroxy-ethyla...)
Affinity DataKi:  72nMAssay Description:Inhibition of bovine cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50053866(Quinoline-2-carboxylic acid [1-(1-ethylaminooxalyl...)
Affinity DataKi:  96nMAssay Description:Inhibition of bovine cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50053860([1-(1-{2-[3-(3,4-Dichloro-phenoxy)-phenyl]-2-hydro...)
Affinity DataKi:  100nMAssay Description:Inhibition of bovine cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50053808({1-[1-(2,2-Diethoxy-ethylaminooxalyl)-propylcarbam...)
Affinity DataKi:  110nMAssay Description:Inhibition of bovine cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM50053818((1-{1-[2-Hydroxy-2-(3-trifluoromethyl-phenyl)-ethy...)
Affinity DataKi:  110nMAssay Description:Inhibition of bovine cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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