TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataKd: 240nMAssay Description:Dissociation constant was determined in presence of Rev Response Element RNA IIBMore data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataKd: 10nMAssay Description:Tested for the ability to bind the HIV-1 RRE-RNA construct by fluorescence anisotropyMore data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataKd: 3.69E+3nMAssay Description:Tested for the ability to bind the HIV-1 RRE-RNA construct by fluorescence anisotropyMore data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataKd: 4.11E+3nMAssay Description:Tested for the ability to bind the HIV-1 RRE-RNA construct by fluorescence anisotropyMore data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataKd: 500nMAssay Description:Tested for the ability to bind the HIV-1 RRE-RNA construct by fluorescence anisotropyMore data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataKd: 160nMAssay Description:Tested for the ability to bind the HIV-1 RRE-RNA construct by fluorescence anisotropyMore data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataKd: 3.40nMAssay Description:Dissociation constant was determined for Rev Response Element RNA IIBMore data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataKd: 8.5nMAssay Description:Dissociation constant was determined for Rev Response Element RNA IIBMore data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataKd: 180nMAssay Description:Tested for the ability to bind the HIV-1 RRE-RNA construct by fluorescence anisotropyMore data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibitory activity against peptide binding to the Rev Response Element RNA IIB was determinedMore data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Inhibitory activity against peptide binding to the RRE RNA was determinedMore data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 690nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H]Rev response element binding to HIV1 biotinylated-Rev protein expressed in Escherichia coli after 15 mins by scintillation proximit...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of exemplary compounds of the invention to inhibit CRM1-mediated nuclear export was assessed in a RevGFP assay. Rev is a protein from hum...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of exemplary compounds of the invention to inhibit CRM1-mediated nuclear export was assessed in a RevGFP assay. Rev is a protein from hum...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of exemplary compounds of the invention to inhibit CRM1-mediated nuclear export was assessed in a RevGFP assay. Rev is a protein from hum...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of exemplary compounds of the invention to inhibit CRM1-mediated nuclear export was assessed in a RevGFP assay. Rev is a protein from hum...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of exemplary compounds of the invention to inhibit CRM1-mediated nuclear export was assessed in a RevGFP assay. Rev is a protein from hum...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.05E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.36E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 3.04E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 4.53E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 5.22E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of [3H]Rev response element binding to HIV1 biotinylated-Rev protein expressed in Escherichia coli after 15 mins by scintillation proximit...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 6.30E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 6.50E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 7.26E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 7.86E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 8.31E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 8.34E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 8.38E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 8.39E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 8.39E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 8.44E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 9.53E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 9.78E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.01E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.01E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.04E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.11E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.14E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.22E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.24E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.39E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.42E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.43E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.48E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.48E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.58E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Graduate School of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.62E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
