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Report error Found 6585 of affinity data for UniProtKB/TrEMBL: P03951
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50458533(CHEMBL4206890)
Affinity DataKd:  1.40E+6nMAssay Description:Inhibition of human factor 11a assessed as reduction in para-nitroanilide releasee using pyroGlu-Pro-Arg-pNA.HCl substrate by by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50582335(CHEMBL5082201)
Affinity DataEC50:  39nMAssay Description:Inhibition of human coagulation factor 11 assessed as inhibition of factor 12a mediated activation measured after 60 mins by fluorescence based micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50582336(CHEMBL5086359)
Affinity DataEC50:  30nMAssay Description:Inhibition of human coagulation factor 11 assessed as inhibition of factor 12a mediated activation measured after 60 mins by fluorescence based micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50582337(CHEMBL5088355)
Affinity DataEC50:  37nMAssay Description:Inhibition of human coagulation factor 11 assessed as inhibition of factor 12a mediated activation measured after 60 mins by fluorescence based micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50582338(CHEMBL5090234)
Affinity DataEC50:  29nMAssay Description:Inhibition of human coagulation factor 11 assessed as inhibition of factor 12a mediated activation measured after 60 mins by fluorescence based micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50582339(CHEMBL5069505)
Affinity DataEC50:  25nMAssay Description:Inhibition of human coagulation factor 11 assessed as inhibition of factor 12a mediated activation measured after 60 mins by fluorescence based micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50582340(CHEMBL5075675)
Affinity DataEC50:  37nMAssay Description:Inhibition of human coagulation factor 11 assessed as inhibition of factor 12a mediated activation measured after 60 mins by fluorescence based micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50580355(CHEMBL5093463)
Affinity DataEC50:  8.5nMAssay Description:Inhibition of human coagulation factor 11 assessed as inhibition of factor 12a mediated activation using z-GPR-AFC measured after 60 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50580356(CHEMBL5079764)
Affinity DataEC50:  19nMAssay Description:Inhibition of human coagulation factor 11 assessed as inhibition of factor 12a mediated activation using z-GPR-AFC measured after 60 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50580357(CHEMBL5077411)
Affinity DataEC50:  13nMAssay Description:Inhibition of human coagulation factor 11 assessed as inhibition of factor 12a mediated activation using z-GPR-AFC measured after 60 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50580358(CHEMBL5082014)
Affinity DataEC50:  4.30nMAssay Description:Inhibition of human coagulation factor 11 assessed as inhibition of factor 12a mediated activation using z-GPR-AFC measured after 60 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50580359(CHEMBL5086001)
Affinity DataEC50:  8.80nMAssay Description:Inhibition of human coagulation factor 11 assessed as inhibition of factor 12a mediated activation using z-GPR-AFC measured after 60 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50580360(CHEMBL5080508)
Affinity DataEC50:  3.80nMAssay Description:Inhibition of human coagulation factor 11 assessed as inhibition of factor 12a mediated activation using z-GPR-AFC measured after 60 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50427855(CHEMBL2326343)
Affinity DataKd:  8.40E+4nMAssay Description:Binding affinity to human factor 11a-DEGR by spectrofluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50612148(CHEMBL5289136)
Affinity DataKd:  3.65E+5nMAssay Description:Binding affinity to active site dansylated human DEGR-FXIa assessed as change in fluorescence intensity by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50427854(CHEMBL2326344)
Affinity DataKd:  9.10E+4nMAssay Description:Binding affinity to human factor 11a-DEGR by spectrofluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50612136(CHEMBL5271926)
Affinity DataKd:  1.99E+4nMAssay Description:Binding affinity to active site dansylated human DEGR-FXIa assessed as change in fluorescence intensity by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011523(CHEMBL3262555)
Affinity DataKd:  4.50E+3nMAssay Description:Binding affinity to fluorescein-EGR-labeled human factor-11a by fluorescence spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011525(CHEMBL2396787)
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity to fluorescein-EGR-labeled human factor-11a by fluorescence spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50427852(CHEMBL2326346)
Affinity DataKd:  3.80E+4nMAssay Description:Binding affinity to human factor 11a-DEGR by spectrofluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50427853(CHEMBL2326345)
Affinity DataKd:  3.70E+4nMAssay Description:Binding affinity to human factor 11a-DEGR by spectrofluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM345099(US9783530, 44 | 4-[(2-{5-[5-chloro-2-(1H- tetrazol...)
Affinity DataIC50: 0.0700nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; JT Ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM304228(BDBM304229 | 2-(1-((4-carboxy-3- fluorophenyl)amin...)
Affinity DataIC50: 0.100nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM620037(US20230295157, Example 362 | (3S,8aR*)-3-(5-(1H-py...)
Affinity DataIC50: 0.100nMAssay Description:A fluorescence intensity (FLINT) based assay was used to monitor inhibition of Factor XIa. The peptide substrate, 5Fam-KLTRAETV-K5Tamra (purchased fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50514063(CHEMBL4447001)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of human factor 11a preincubated for 15 mins followed by Boc-Glu (OBzl) -Ala-Arg-AMC and measured after 30 mins by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM304126((R)-trans-4-{[2-{5-[3-chloro-6-(difluoromethoxy)-2...)
Affinity DataIC50: 0.140nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM345082(4-{[(2R)-2-{5-[5-chloro-2- (1H-tetrazol-1-yl)pheny...)
Affinity DataIC50: 0.140nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; JT Ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM345057(4-{[(2R)-2-{5-[5-chloro- 2-(1H-tetrazol-1- yl)phen...)
Affinity DataIC50: 0.160nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; JT Ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM588063(US11541049, Example 5)
Affinity DataIC50: 0.160nMAssay Description:Reagents:Enzyme: human coagulation factor XIa; manufacturer: Haemtech;Substrate: Boc-Ile-Glu-Gly-Arg-AMC Acetate salt; manufacturer: Bachem;Reaction ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50593279(CHEMBL5196642)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of human coagulation factor XIa using GPR-AFC as substrate preincubated for 30 mins followed by substrate addition and measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM285900(7-(5-(5-carboxythiophen-3-yl)-4-chloro-1H-imidazol...)
Affinity DataIC50: 0.170nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; JT Ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2019
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM304171(US10143681, Example 63 | 2-((2R)-1-((4- carboxyphe...)
Affinity DataIC50: 0.190nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM345105(4-[(2-{5-[3-chloro-2- fluoro-6-(1H-tetrazol-1- yl)...)
Affinity DataIC50: 0.190nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; JT Ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50593277(CHEMBL5183661)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of human coagulation factor XIa using GPR-AFC as substrate preincubated for 30 mins followed by substrate addition and measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM619887(US20230295157, Example 211 | 5-(5-Chloro-2-((3S,8a...)
Affinity DataIC50: 0.200nMAssay Description:A fluorescence intensity (FLINT) based assay was used to monitor inhibition of Factor XIa. The peptide substrate, 5Fam-KLTRAETV-K5Tamra (purchased fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM619914(US20230295157, Example 238 | 5-(2-((3*S,8aR)-7-(3-...)
Affinity DataIC50: 0.200nMAssay Description:A fluorescence intensity (FLINT) based assay was used to monitor inhibition of Factor XIa. The peptide substrate, 5Fam-KLTRAETV-K5Tamra (purchased fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM619925(US20230295157, Example 249 | N-(4-(2-((3S,8a*R)-7-...)
Affinity DataIC50: 0.200nMAssay Description:A fluorescence intensity (FLINT) based assay was used to monitor inhibition of Factor XIa. The peptide substrate, 5Fam-KLTRAETV-K5Tamra (purchased fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM619926(US20230295157, Example 250 | N-(4-(24(3S,8aS*)-7-(...)
Affinity DataIC50: 0.200nMAssay Description:A fluorescence intensity (FLINT) based assay was used to monitor inhibition of Factor XIa. The peptide substrate, 5Fam-KLTRAETV-K5Tamra (purchased fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM619946(US20230295157, Example 270)
Affinity DataIC50: 0.200nMAssay Description:A fluorescence intensity (FLINT) based assay was used to monitor inhibition of Factor XIa. The peptide substrate, 5Fam-KLTRAETV-K5Tamra (purchased fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM619953(US20230295157, Example 277 | 6-(2-((3S,8aR)-7-(3-C...)
Affinity DataIC50: 0.200nMAssay Description:A fluorescence intensity (FLINT) based assay was used to monitor inhibition of Factor XIa. The peptide substrate, 5Fam-KLTRAETV-K5Tamra (purchased fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM619989(US20230295157, Example 313 | (3S)-3-(5-(3-Amino-1H...)
Affinity DataIC50: 0.200nMAssay Description:A fluorescence intensity (FLINT) based assay was used to monitor inhibition of Factor XIa. The peptide substrate, 5Fam-KLTRAETV-K5Tamra (purchased fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM620017(US20230295157, Example 341 | Methyl (4-(2-((3S,8aR...)
Affinity DataIC50: 0.200nMAssay Description:A fluorescence intensity (FLINT) based assay was used to monitor inhibition of Factor XIa. The peptide substrate, 5Fam-KLTRAETV-K5Tamra (purchased fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM620029(US20230295157, Example 354 | (3S,8aR)-3-(5-(6-Amin...)
Affinity DataIC50: 0.200nMAssay Description:A fluorescence intensity (FLINT) based assay was used to monitor inhibition of Factor XIa. The peptide substrate, 5Fam-KLTRAETV-K5Tamra (purchased fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM620030(US20230295157, Example 355 | Methyl (4-(2-((3S)-7-...)
Affinity DataIC50: 0.200nMAssay Description:A fluorescence intensity (FLINT) based assay was used to monitor inhibition of Factor XIa. The peptide substrate, 5Fam-KLTRAETV-K5Tamra (purchased fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM620044(US20230295157, Example 369 | N-(2-(2-((3S,8aR)-7-(...)
Affinity DataIC50: 0.200nMAssay Description:A fluorescence intensity (FLINT) based assay was used to monitor inhibition of Factor XIa. The peptide substrate, 5Fam-KLTRAETV-K5Tamra (purchased fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM620045(US20230295157, Example 370 | N-(4-(2-((3S)-7-(3-ch...)
Affinity DataIC50: 0.200nMAssay Description:A fluorescence intensity (FLINT) based assay was used to monitor inhibition of Factor XIa. The peptide substrate, 5Fam-KLTRAETV-K5Tamra (purchased fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM285973(US10081617, Example 120 | (7S)-7-[5-(4-aminophenyl...)
Affinity DataIC50: 0.207nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; JT Ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2019
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM304171(US10143681, Example 63 | 2-((2R)-1-((4- carboxyphe...)
Affinity DataIC50: 0.210nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM588060(US11541049, Example 2)
Affinity DataIC50: 0.210nMAssay Description:Reagents:Enzyme: human coagulation factor XIa; manufacturer: Haemtech;Substrate: Boc-Ile-Glu-Gly-Arg-AMC Acetate salt; manufacturer: Bachem;Reaction ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM345061(2-{5-[5-chloro-2-(1H- tetrazol-1-yl)phenyl]-1- oxi...)
Affinity DataIC50: 0.240nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; JT Ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
Go to US Patent

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