Compile Data Set for Download or QSAR
Report error Found 46 of affinity data for UniProtKB/TrEMBL: P00636
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM4626(CHEMBL301018 | N-(3-chloro-4-fluorophenyl)-6,7-dim...)
Affinity DataIC50: 340nMAssay Description:Compound was evaluated for its concentration required to inhibit the porcine kidney F16BPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50095256((6,7-Dimethoxy-quinazolin-4-yl)-(3-ethynyl-4-fluor...)
Affinity DataIC50: 770nMAssay Description:Compound was evaluated for its concentration required to inhibit the porcine kidney F16BPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50004952(CHEMBL31344 | 3-(2-Carboxy-ethyl)-4,6-dichloro-1H-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against Fructose-1,6-bisphosphatase (F16BPase) in porcine kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293592(4-(2-amino-1,3-thiazol-4-yl)phenol | 4-(2-Aminothi...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM18137(adenosine 5 -monophosphate | CHEMBL752 | [(2R,3S,4...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of pig kidney fructose-1,6-bisphosphatase expressed in Escherichia coli BL21 (DE3) assessed as reduction of NADP+ to NADPH by phosphogluco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM18137(adenosine 5 -monophosphate | CHEMBL752 | [(2R,3S,4...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316378(US9273021, 3 | 1,1'-(1,3,7,9-Tetrahydroxydibenzofu...)
Affinity DataIC50: 1.50E+3nMpH: 7.5Assay Description:FBPase activity was measured spectrophotometrically by employing the coupling enzymes phosphoglucose isomerase and glucose-6-phosphate dehydrogenase....More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316378(US9273021, 3 | 1,1'-(1,3,7,9-Tetrahydroxydibenzofu...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of pig kidney fructose-1,6-bisphosphatase expressed in Escherichia coli BL21 (DE3) assessed as reduction of NADP+ to NADPH by phosphogluco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50095259(N-(3-ethynylphenyl)-6,7-dimethoxyquinazolin-4-amin...)
Affinity DataIC50: 1.60E+3nMAssay Description:Compound was evaluated for its concentration required to inhibit the porcine kidney F16BPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50095266((3-Chloro-4-fluoro-phenyl)-(6,7-diethoxy-quinazoli...)
Affinity DataIC50: 3.10E+3nMAssay Description:Compound was evaluated for its concentration required to inhibit the porcine kidney F16BPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50095261(4-(3'-chloroanilino)-6,7-diethoxyquinazoline hydro...)
Affinity DataIC50: 3.90E+3nMAssay Description:Compound was evaluated for its concentration required to inhibit the porcine kidney F16BPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316379(US9273021, 4 | 1,1'-(1,3,7,9-Tetrahydroxydibenzofu...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of pig kidney fructose-1,6-bisphosphatase expressed in Escherichia coli BL21 (DE3) assessed as reduction of NADP+ to NADPH by phosphogluco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316379(US9273021, 4 | 1,1'-(1,3,7,9-Tetrahydroxydibenzofu...)
Affinity DataIC50: 5.00E+3nMpH: 7.5Assay Description:FBPase activity was measured spectrophotometrically by employing the coupling enzymes phosphoglucose isomerase and glucose-6-phosphate dehydrogenase....More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293581(4-(2-(3-Hydroxyphenylamino)thiazol-4-yl)benzene-1,...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM3032(CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was evaluated for its concentration required to inhibit the porcine kidney F16BPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM3556(PD153035 Analog | 4-[(3-Bromophenyl)amino]-6,7-die...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was evaluated for its concentration required to inhibit the porcine kidney F16BPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM3532(CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was evaluated for its concentration required to inhibit the porcine kidney F16BPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293578(4-(2-(4-Hydroxyphenylamino)thiazol-4-yl)benzene-1,...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293580(3-(4-(4-Hydroxyphenyl)thiazol-2-ylamino)phenol | C...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293583(2-(4-(4-Hydroxyphenyl)thiazol-2-ylamino)phenol | C...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293584(4-(2-(2-Hydroxyphenylamino)thiazol-4-yl)benzene-1,...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293596(methyl 4-ethyl-5-methyl-2-(3-(pyridin-2-ylmethyl)t...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293572(4-(4-(4-Hydroxyphenyl)thiazol-2-ylamino)benzenesul...)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293572(4-(4-(4-Hydroxyphenyl)thiazol-2-ylamino)benzenesul...)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293579(3-(4-Phenylthiazol-2-ylamino)phenol | CHEMBL554135)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293586(4-(2-(3-Nitrophenylamino)thiazol-4-yl)phenol | CHE...)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293591(3-(4-(4-hydroxyphenyl)thiazol-2-ylamino)benzoic ac...)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293577(cid_972292 | CHEMBL563294 | 4-(4-(4-Hydroxyphenyl)...)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293575(3-(4-(4-Hydroxyphenyl)thiazol-2-ylamino)benzenesul...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293573(CHEMBL239103 | cid_2175556 | 4-(4-(2,4-dihydroxyph...)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293593(4-(2-aminothiazol-4-yl)benzene-1,3-diol | CHEMBL54...)
Affinity DataIC50: 9.30E+4nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293574(3-(4-Phenylthiazol-2-ylamino)benzenesulfonamide | ...)
Affinity DataIC50: 1.04E+5nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293589(2-(2-(Phenylamino)thiazol-4-yl)phenol | CHEMBL5628...)
Affinity DataIC50: 1.19E+5nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293576(CHEMBL562493 | 4131JH0380 | 4-(4-phenylthiazol-2-y...)
Affinity DataIC50: 1.24E+5nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293571(4-(4-Phenyl-thiazol-2-ylamino)-benzenesulfonamide ...)
Affinity DataIC50: 1.45E+5nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293585(4-(2-(4-Nitrophenylamino)thiazol-4-yl)phenol | CHE...)
Affinity DataIC50: 2.46E+5nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293582(2-(4-Phenylthiazol-2-ylamino)phenol | CHEMBL555896)
Affinity DataIC50: 2.70E+5nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293587(4-(2-(phenylamino)thiazol-4-yl)phenol | CHEMBL5536...)
Affinity DataIC50: 3.18E+5nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293588(4-(2-(Phenylamino)thiazol-4-yl)benzene-1,3-diol | ...)
Affinity DataIC50: 3.43E+5nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50202829(2,6-diacetyl-3,7,9-trihydroxy-8,9b-dimethyldibenzo...)
Affinity DataIC50: 3.71E+5nMAssay Description:Inhibition of pig kidney fructose-1,6-bisphosphatase expressed in Escherichia coli BL21 (DE3) assessed as reduction of NADP+ to NADPH by phosphogluco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293590(3-(4-phenylthiazol-2-ylamino)benzoic acid | CHEMBL...)
Affinity DataIC50: 5.71E+5nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293597(4-[(4-carboxybenzene)sulfonyl]benzoic acid | 4,4'-...)
Affinity DataIC50: 7.50E+5nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM209638(US9273021, Usnic Acid)
Affinity DataIC50: 9.30E+5nMpH: 7.5Assay Description:FBPase activity was measured spectrophotometrically by employing the coupling enzymes phosphoglucose isomerase and glucose-6-phosphate dehydrogenase....More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293595(1-(3,5-dimethyl-1H-pyrazol-1-yl)-3-(naphthalen-2-y...)
Affinity DataIC50: 3.00E+6nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM31190(thiazol-2-amine, 1 | US20240342139, Compound BL-10...)
Affinity DataIC50: 1.39E+6nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50264074(N,4-Diphenylthiazol-2-amine | CHEMBL510166)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed