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Report error Found 235 of affinity data for UniProtKB/TrEMBL: P00591
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 4nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 4nMAssay Description:Inhibition of porcine pancreatic lipase using p-NPB as substrate pretreated for 15 mins followed by substrate addition measured after 15 mins by spec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50552242(CHEMBL365190)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of porcine pancreatic lipase preincubated for 10 mins followed by 4-MUO addition and measured at 60 sec interval for 40 mins by multi plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50465318(CHEMBL472695)
Affinity DataIC50: 8nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 12nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2017
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50465320(CHEMBL4282840)
Affinity DataIC50: 15nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50465321(CHEMBL4291122)
Affinity DataIC50: 15nMAssay Description:Inhibition of porcine pancreatic lipaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50274723(N-Formyl-D-leucine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50465317(CHEMBL4282614)
Affinity DataIC50: 17nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50465323(CHEMBL4282318)
Affinity DataIC50: 20nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50465319(CHEMBL4290524)
Affinity DataIC50: 77nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50303006(mulberrofuran D | CHEMBL517247)
Affinity DataIC50: 90nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2017
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50595125(CHEMBL5174296)
Affinity DataIC50: 140nMAssay Description:Inhibition of porcine pancreatic lipase using trioleate as substrate assessed as inhibition of substrate hydrolysis measured for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 150nMAssay Description:Inhibition of porcine pancreatic lipase measured after 40 mins by spectrophotocolorimetric enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 220nMAssay Description:Inhibition of porcine pancreatic lipase using micellar solution of triolein as substrate preincubated for 5 mins before substrate addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 300nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenylbutyrate as substrate assessed as formation of p-nitrophenol preincubated for 15 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 300nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenylbutyrate as substrate preincubated for 15 mins prior substrate addition measured after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 320nMAssay Description:Inhibition of porcine pancreatic lipase pre-incubated for 15 mins before p-nitrophenylbutyrate substrate addition by microplate reader based methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50552240(CHEMBL4780197)
Affinity DataIC50: 330nMAssay Description:Inhibition of porcine pancreatic lipase preincubated for 10 mins followed by 4-MUO addition and measured at 60 sec interval for 40 mins by multi plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 360nMAssay Description:Inhibition of porcine pancreatic lipase using triolein as substrate measured after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50168024(CHEMBL3800462)
Affinity DataIC50: 390nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2017
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 400nMAssay Description:Inhibition of porcine pancreatic lipase using pNPB as substrate measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50168022(CHEMBL3797266)
Affinity DataIC50: 480nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2017
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50262486(CHEMBL2354678)
Affinity DataIC50: 500nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate pretreated for 15 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50168023(CHEMBL3800628)
Affinity DataIC50: 570nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2017
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50552238(CHEMBL4788400)
Affinity DataIC50: 580nMAssay Description:Inhibition of porcine pancreatic lipase preincubated for 10 mins followed by 4-MUO addition and measured at 60 sec interval for 40 mins by multi plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 600nMpH: 6.8Assay Description:Particularly, pancreatic lipase inhibiting activity was measured by the conventional method known to those in the art (Kim, J. H.; Kim, H. J.; Park, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 600nMAssay Description:Inhibition of pig pancreatic lipase assessed as p-NPB hydrolysis by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 600nMAssay Description:Inhibition of pig pancreatic lipase assessed as hydrolysis of p-nitrophenylbutyrate to p-nitrophenolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50552241(CHEMBL4797179)
Affinity DataIC50: 680nMAssay Description:Inhibition of porcine pancreatic lipase preincubated for 10 mins followed by 4-MUO addition and measured at 60 sec interval for 40 mins by multi plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50303004(mulberrofuran W | CHEMBL562810)
Affinity DataIC50: 700nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2017
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50168019(CHEMBL3798170)
Affinity DataIC50: 710nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2017
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50367145(CHEMBL4173252)
Affinity DataIC50: 750nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate pretreated for 15 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50168021(CHEMBL3800241)
Affinity DataIC50: 760nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2017
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50367138(CHEMBL4160519)
Affinity DataIC50: 770nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate pretreated for 15 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50367133(CHEMBL4164998)
Affinity DataIC50: 800nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate pretreated for 15 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 800nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate pretreated for 15 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50552236(CHEMBL4782276)
Affinity DataIC50: 830nMAssay Description:Inhibition of porcine pancreatic lipase preincubated for 10 mins followed by 4-MUO addition and measured at 60 sec interval for 40 mins by multi plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50367134(CHEMBL4167341)
Affinity DataIC50: 840nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate pretreated for 15 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50168018(CHEMBL3798236)
Affinity DataIC50: 850nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2017
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50367211(CHEMBL4165339)
Affinity DataIC50: 850nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate pretreated for 15 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50367212(CHEMBL4168413)
Affinity DataIC50: 910nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate pretreated for 15 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50168020(CHEMBL3797932)
Affinity DataIC50: 920nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2017
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50465322(CHEMBL2305145)
Affinity DataIC50: 930nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50367214(CHEMBL4163899)
Affinity DataIC50: 950nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate pretreated for 15 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 990nMAssay Description:Inhibition of porcine pancreatic lipase assessed as reduction in 4-nitrophenol formation from 4-nitrophenyl butyrate substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 990nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate preincubated for 5 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50552233(CHEMBL4748399)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of porcine pancreatic lipase preincubated for 10 mins followed by 4-MUO addition and measured at 60 sec interval for 40 mins by multi plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50552234(CHEMBL4757866)
Affinity DataIC50: 2.09E+3nMAssay Description:Inhibition of porcine pancreatic lipase preincubated for 10 mins followed by 4-MUO addition and measured at 60 sec interval for 40 mins by multi plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50552237(CHEMBL4744746)
Affinity DataIC50: 2.52E+3nMAssay Description:Inhibition of porcine pancreatic lipase preincubated for 10 mins followed by 4-MUO addition and measured at 60 sec interval for 40 mins by multi plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
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