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Report error Found 135 of affinity data for UniProtKB/TrEMBL: O89049
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385274(CHEMBL2035489)
Affinity DataIC50: 130nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50551265(CHEMBL4792536)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant rat TrxR1 using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by color...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50127227((R)-2,4,6-Trimethyl-deca-2,4-dienoic acid {(1S,5S,...)
Affinity DataIC50: 272nMAssay Description:Inhibition of NADPH-reduced recombinant rat TrxR1 expressed in Escherichia coli harboring gor mutant assessed as suppression of DTNB reduction pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385288(CHEMBL2034987)
Affinity DataIC50: 280nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385273(CHEMBL2035491)
Affinity DataIC50: 320nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385303(CHEMBL2035460 | US8592468, EbSe14)
Affinity DataIC50: 350nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385279(CHEMBL2035484)
Affinity DataIC50: 570nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50127227((R)-2,4,6-Trimethyl-deca-2,4-dienoic acid {(1S,5S,...)
Affinity DataIC50: 572nMAssay Description:Inhibition of NADPH-reduced recombinant rat TrxR1 expressed in Escherichia coli harboring gor mutant assessed as suppression of insulin reduction usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50551269(CHEMBL4745896)
Affinity DataIC50: 590nMAssay Description:Inhibition of recombinant rat TrxR1 using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by color...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50515528(CHEMBL4459518)
Affinity DataIC50: 600nMAssay Description:Inhibition of rat TrxR1 using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50515528(CHEMBL4459518)
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant rat TrxR1 using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by color...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM33201(MLS001048870 | cid_271296 | 2-methyl-5,8-bis(oxida...)
Affinity DataIC50: 700nMAssay Description:Inhibition of NADPH-reduced rat TrxR1 assessed as suppression of DTNB reduction incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2020
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385302(CHEMBL2035461 | US8592468, EbSe15)
Affinity DataIC50: 780nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385278(CHEMBL2035485)
Affinity DataIC50: 820nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385287(CHEMBL2035476)
Affinity DataIC50: 860nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50515538(CHEMBL4562297)
Affinity DataIC50: 930nMAssay Description:Inhibition of rat TrxR1 using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385301(CHEMBL2035462)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385292(CHEMBL2035471)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50515537(CHEMBL4589636)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of rat TrxR1 using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385293(CHEMBL2035470)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385283(CHEMBL2035480)
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50551268(CHEMBL4793784)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant rat TrxR1 using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by color...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385281(CHEMBL2035482)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50127227((R)-2,4,6-Trimethyl-deca-2,4-dienoic acid {(1S,5S,...)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of NADPH-reduced recombinant rat TrxR1 expressed in Escherichia coli harboring gor mutant assessed as suppression of DTNB reduction incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385280(CHEMBL2035483)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385286(CHEMBL2035477)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385299(CHEMBL2035464 | US8592468, EbSe16)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50515536(CHEMBL4577957)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of rat TrxR1 using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385282(CHEMBL2035481)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385300(CHEMBL2035463)
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50633108(CHEMBL5430918)
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of recombinant rat TrxR1 incubated for 1 hr in presence of NADPH by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385305(CHEMBL2035472)
Affinity DataIC50: 2.38E+3nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50236287(CHEMBL4071967)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant rat liver thioredoxin reductase after 60 mins by DTNB reduction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2019
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385276(CHEMBL2035487)
Affinity DataIC50: 2.87E+3nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385277(CHEMBL2035486)
Affinity DataIC50: 2.91E+3nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50633100(CHEMBL5412818)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant rat TrxR1 incubated for 1 hr in presence of NADPH by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50515527(CHEMBL4451049)
Affinity DataIC50: 3.12E+3nMAssay Description:Inhibition of rat TrxR1 using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385291(CHEMBL2035473)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50551264(CHEMBL4791226)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant rat TrxR1 using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by color...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50551267(CHEMBL4754210)
Affinity DataIC50: 3.37E+3nMAssay Description:Inhibition of recombinant rat TrxR1 using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by color...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50633109(CHEMBL5417326)
Affinity DataIC50: 3.69E+3nMAssay Description:Inhibition of recombinant rat TrxR1 incubated for 1 hr in presence of NADPH by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50633107(CHEMBL5417869)
Affinity DataIC50: 3.74E+3nMAssay Description:Inhibition of recombinant rat TrxR1 incubated for 1 hr in presence of NADPH by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50236319(CHEMBL4101407)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of recombinant rat liver thioredoxin reductase after 60 mins by DTNB reduction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2019
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385285(CHEMBL2035478)
Affinity DataIC50: 3.87E+3nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50236321(CHEMBL4097389)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of recombinant rat liver thioredoxin reductase after 60 mins by DTNB reduction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2019
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50236287(CHEMBL4071967)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of recombinant rat liver thioredoxin reductase after 30 mins by DTNB reduction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2019
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50515531(CHEMBL4452177)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of rat TrxR1 using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50333880(Hypericin | CHEMBL1614664 | Pseudohypericin)
Affinity DataIC50: 4.41E+3nMAssay Description:Inhibition of rat liver cytosolic TrxR1 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385297(CHEMBL2035466)
Affinity DataIC50: 4.49E+3nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Peking University

Curated by ChEMBL
LigandPNGBDBM50385275(CHEMBL2035488)
Affinity DataIC50: 4.54E+3nMAssay Description:Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
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