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Report error Found 40 of affinity data for UniProtKB/TrEMBL: O78749
TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679764(US12011433, Compound mofezolac)
Affinity DataIC50: 7.90nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
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TargetCytochrome c oxidase subunit 1(Sheep)
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US Patent
LigandPNGBDBM679777(US12011433, Compound MPA361)
Affinity DataIC50: 13nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
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TargetCytochrome c oxidase subunit 1(Sheep)
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US Patent
LigandPNGBDBM679784(US12011433, Compound MPA439)
Affinity DataIC50: 49nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
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TargetCytochrome c oxidase subunit 1(Sheep)
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US Patent
LigandPNGBDBM679768(US12011433, Compound MPA195)
Affinity DataIC50: 70nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
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TargetCytochrome c oxidase subunit 1(Sheep)
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US Patent
LigandPNGBDBM679782(US12011433, Compound MPA462)
Affinity DataIC50: 80nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
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TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679767(US12011433, Compound GAMOF11)
Affinity DataIC50: 100nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
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TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679770(US12011433, Compound MPA190)
Affinity DataIC50: 100nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
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TargetCytochrome c oxidase subunit 1(Sheep)
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US Patent
LigandPNGBDBM679765(US12011433, Compound GlaMOF0)
Affinity DataIC50: 100nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679781(US12011433, Compound MPA415)
Affinity DataIC50: 150nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679772(US12011433, Compound MPA230)
Affinity DataIC50: 700nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
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TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM50556692(CHEMBL4789452 | US12011433, MPA 290)
Affinity DataIC50: 950nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
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TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679773(US12011433, Compound 270)
Affinity DataIC50: 1.10E+3nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679769(US12011433, Compound MPA199)
Affinity DataIC50: 3.30E+3nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679780(US12011433, Compound MPA354)
Affinity DataIC50: 5.50E+3nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679776(US12011433, Compound MPA15(DQ3))
Affinity DataIC50: 6.00E+3nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM50513906(CHEMBL4549769)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of ovine COX1 preincubated for 5 mins followed by arachidonic acid addition and measured after 2 mins by colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of ovine COX1 preincubated for 5 mins followed by arachidonic acid addition and measured after 2 mins by colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679779(US12011433, Compound MPA434)
Affinity DataIC50: 7.10E+3nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679778(US12011433, Compound MPA448)
Affinity DataIC50: 9.00E+3nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM50326826(2-(4-acetamido)phenyl)-8-benzoyl-quinoline-4-carbo...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of sheep COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM50300870(2-(4-(methylsulfonyl)phenyl)-quinoline-4-carboxyli...)
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of sheep COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM50326828(8-benzoyl-2-(4-(methylsulfonyl)phenyl)quinoline-4-...)
Affinity DataIC50: 1.59E+4nMAssay Description:Inhibition of sheep COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679786(US12011433, Compound MPA362)
Affinity DataIC50: 1.60E+4nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679785(US12011433, Compound MPA450)
Affinity DataIC50: 1.70E+4nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM50515745(CHEMBL4474644)
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGF2alpha incubated for 2 mins using arachidonic acid as substrate by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM50326827(2-(4-acetamido)phenyl)-6-benzoyl-quinoline-4-carbo...)
Affinity DataIC50: 2.18E+4nMAssay Description:Inhibition of sheep COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 2.43E+4nMAssay Description:Inhibition of sheep COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM50326829(6-benzoyl-2-(4-(methylsulfonyl)phenyl)quinoline-4-...)
Affinity DataIC50: 2.44E+4nMAssay Description:Inhibition of sheep COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 2.73E+4nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGF2alpha incubated for 2 mins using arachidonic acid as substrate by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM50524076(CHEMBL4483707)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of ovine COX1 assessed as reduction in prostaglandin E2 production incubated for 10 mins before arachidonic acid addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM50515744(CHEMBL4441570)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGF2alpha incubated for 2 mins using arachidonic acid as substrate by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM50515743(CHEMBL4448990)
Affinity DataIC50: 3.99E+4nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGF2alpha incubated for 2 mins using arachidonic acid as substrate by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679771(US12011433, Compound MPA239)
Affinity DataIC50: 5.00E+4nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679783(US12011433, Compound MPA422)
Affinity DataIC50: 5.00E+4nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679775(US12011433, Compound MPA236)
Affinity DataIC50: 5.00E+4nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM679766(US12011433, Compound GlaMOF5)
Affinity DataIC50: 5.00E+4nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent

TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM50326830(2-(4-azido)phenyl)-8-benzoyl-quinoline-4-carboxyli...)
Affinity DataIC50: 6.56E+4nMAssay Description:Inhibition of sheep COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM13063(CHEMBL865 | cid_119607 | Bextra | VLX | 4-(5-methy...)
Affinity DataIC50: 9.62E+4nMAssay Description:Inhibition of ovine cyclooxygenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM50326831(2-(4-azido)phenyl)-6-benzoyl-quinoline-4-carboxyli...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of sheep COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM50229774(N-hydroxy-4-(5-methyl-3-phenylisoxazol-4-yl)benzen...)
Affinity DataIC50: 1.57E+5nMAssay Description:Inhibition of ovine cyclooxygenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed