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Report error Found 411 of affinity data for UniProtKB/TrEMBL: O60725
TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50502491(CHEMBL4443354 | US11834430, Compound 41)
Affinity DataIC50: 0.00200nMAssay Description:Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50502491(CHEMBL4443354 | US11834430, Compound 41)
Affinity DataIC50: 0.00200nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50502493(CHEMBL4558383 | US11834430, Compound 81)
Affinity DataIC50: 0.00300nMAssay Description:Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50502489(CHEMBL4583704 | US11834430, Compound 72)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637711(US11834430, Compound 29 | 3-methoxy-4-((1-(3- (2-m...)
Affinity DataIC50: 0.0800nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50502494(CHEMBL4446351 | US11834430, Compound 9)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50502494(CHEMBL4446351 | US11834430, Compound 9)
Affinity DataIC50: 0.100nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637738(US11834430, Compound 56 | (S)-3-chloro-4-((1- (3-(...)
Affinity DataIC50: 0.150nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50502488(CHEMBL4449942 | US11834430, Compound 62)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50502488(CHEMBL4449942 | US11834430, Compound 62)
Affinity DataIC50: 0.170nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50502486(CHEMBL4468997 | US11834430, Compound 5)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50502492(CHEMBL4446048 | US11834430, Compound 8)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50502492(CHEMBL4446048 | US11834430, Compound 8)
Affinity DataIC50: 0.200nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637731(US11834430, Compound 49 | (S)-4-((1-(3-(2- cyclopr...)
Affinity DataIC50: 0.300nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637758(US11834430, Compound 76 | 4-(2-((2-(2- cyclopropyl...)
Affinity DataIC50: 0.390nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637735(US11834430, Compound 53 | 3-fluoro-4-(2-((2-(2- me...)
Affinity DataIC50: 0.440nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637730(US11834430, Compound 48 | (R)-3-methoxy-4- ((1-(3-...)
Affinity DataIC50: 0.640nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50502489(CHEMBL4583704 | US11834430, Compound 72)
Affinity DataIC50: 0.680nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50502490(CHEMBL4464629 | US11834430, Compound 47)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637719(US11834430, Compound 37 | 3-fluoro-4-((1-(3-(1- me...)
Affinity DataIC50: 0.700nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637759(US11834430, Compound 77 | (R)-3-methoxy-4- ((1-(3-...)
Affinity DataIC50: 0.700nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637742(US11834430, Compound 60 | (S)-3-methoxy-4- ((1-(3-...)
Affinity DataIC50: 0.810nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637743(US11834430, Compound 61 | 4-((1-(3-(2- cyclopropyl...)
Affinity DataIC50: 0.880nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50502487(CHEMBL4473893 | US11834430, Compound 15)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50348075(CHEMBL1800705)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant C-terminal His6-tagged ICMT assessed as methylation of N-acetyl-S-geranylgeranylcysteine using SAM as methyl donor su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637706(US11834430, Compound 24 | 3-chloro-4-(2-((2-(2- me...)
Affinity DataIC50: 1nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637728(US11834430, Compound 46 | (R)-3-fluoro-4-((1- (3-(...)
Affinity DataIC50: 1nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50502493(CHEMBL4558383 | US11834430, Compound 81)
Affinity DataIC50: 1nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50502487(CHEMBL4473893 | US11834430, Compound 15)
Affinity DataIC50: 1.10nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637713(US11834430, Compound 31 | 3-methoxy-4-((1-(3- (1-m...)
Affinity DataIC50: 1.20nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637715(US11834430, Compound 33 | (S)-3-chloro-4-(2- (3-(2...)
Affinity DataIC50: 1.5nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637750(US11834430, Compound 68 | (R)-4-((1-(3-(2- cyclopr...)
Affinity DataIC50: 1.5nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50502495(CHEMBL4445788 | US11834430, Compound 40)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637710(US11834430, Compound 28 | 4-((1-(3-(2- cyclopropyl...)
Affinity DataIC50: 1.60nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637712(US11834430, Compound 30 | 3-methyl-4-((1-(3- (1-me...)
Affinity DataIC50: 1.60nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637776(US11834430, Compound 94 | 4-(2-(3-fluoro-5-(1- met...)
Affinity DataIC50: 1.60nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637786(US11834430, Compound 104 | 4-(2-(4-bromo-2- fluoro...)
Affinity DataIC50: 1.70nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637782(US11834430, Compound 100 | 3-chloro-4-(2-((2-(1- m...)
Affinity DataIC50: 1.80nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637688(US11834430, Compound 6 | 3-fluoro-4-(2-(3-(2- meth...)
Affinity DataIC50: 2nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637800(US11834430, Compound 118 | 3-chloro-4-(2-(3-(1- cy...)
Affinity DataIC50: 2.20nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637781(US11834430, Compound 99 | 5-chloro-2-(2-((2-(2- me...)
Affinity DataIC50: 2.60nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637751(US11834430, Compound 69 | 3-fluoro-4-(2-((2-(1- me...)
Affinity DataIC50: 2.80nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637771(US11834430, Compound 89 | 4-(2-((2-(2- cyclopropyl...)
Affinity DataIC50: 2.80nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50502486(CHEMBL4468997 | US11834430, Compound 5)
Affinity DataIC50: 3nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637689(US11834430, Compound 7 | 3-chloro-4-(2-(3-(1- meth...)
Affinity DataIC50: 3nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637700(US11834430, Compound 18 | 5-methyl-2-(2-(3-(1- met...)
Affinity DataIC50: 3nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637704(US11834430, Compound 22 | 3-chloro-4-(2-(3-(2- met...)
Affinity DataIC50: 3nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637785(US11834430, Compound 103 | 4-(2-(4-chloro-2- fluor...)
Affinity DataIC50: 3.10nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637717(US11834430, Compound 35 | (S)-3-fluoro-4-(2-(3- (2...)
Affinity DataIC50: 3.60nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
Go to US Patent

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM637734(US11834430, Compound 52 | 3-amino-4-(2-(3-(2- cycl...)
Affinity DataIC50: 3.60nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
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