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Report error Found 61 of affinity data for UniProtKB/TrEMBL: O60427
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50245999(CHEMBL4084502)
Affinity DataIC50: 0.520nMAssay Description:Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50576738(CHEMBL4856454)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Delta-5-desaturase (unknown origin) expressed in HEK2936E cell membrane incubated for 1 hr by DGLA-CoA and Arachidonyl-CoA mass spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50576739(CHEMBL4879015)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Delta-5-desaturase (unknown origin) expressed in HEK2936E cell membrane incubated for 1 hr by DGLA-CoA and Arachidonyl-CoA mass spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50615159(CHEMBL5278664)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human Delta 5 desaturase (unknown origin) expressed in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50245998(CHEMBL4064555)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50576734(CHEMBL4874614)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Delta-5-desaturase (unknown origin) expressed in HEK2936E cell membrane incubated for 1 hr by DGLA-CoA and Arachidonyl-CoA mass spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50576736(CHEMBL4872983)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Delta-5-desaturase (unknown origin) expressed in HEK2936E cell membrane incubated for 1 hr by DGLA-CoA and Arachidonyl-CoA mass spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50535222(CHEMBL4439992)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of D5D in human HepG2 cells using [14C]DGLA as substrate preincubated for 30 mins followed by substrate addition measured after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50576737(CHEMBL4855704)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of Delta-5-desaturase (unknown origin) expressed in HEK2936E cell membrane incubated for 1 hr by DGLA-CoA and Arachidonyl-CoA mass spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50576735(CHEMBL4868627)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of Delta-5-desaturase (unknown origin) expressed in HEK2936E cell membrane incubated for 1 hr by DGLA-CoA and Arachidonyl-CoA mass spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246049(CHEMBL4102458)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246023(CHEMBL4060775)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116774(CHEMBL3608796)
Affinity DataIC50: 5nMAssay Description:Inhibition of liver delta-5 desaturase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116776(CHEMBL3608798)
Affinity DataIC50: 6nMAssay Description:Inhibition of liver delta-5 desaturase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116778(CHEMBL3608800)
Affinity DataIC50: 8nMAssay Description:Inhibition of liver delta-5 desaturase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246000(CHEMBL4070383)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246000(CHEMBL4070383)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM3263(CHEMBL329672 | N-(3-chlorophenyl)quinazolin-4-amin...)
Affinity DataIC50: 11nMAssay Description:Inhibition of liver delta-5 desaturase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116702(CHEMBL3608697)
Affinity DataIC50: 15nMAssay Description:Inhibition of liver delta-5 desaturase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116709(CHEMBL3608700)
Affinity DataIC50: 17nMAssay Description:Inhibition of liver delta-5 desaturase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246045(CHEMBL4090490)
Affinity DataIC50: 18nMAssay Description:Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116700(CHEMBL3608699)
Affinity DataIC50: 18nMAssay Description:Inhibition of liver delta-5 desaturase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116775(CHEMBL3608797)
Affinity DataIC50: 21nMAssay Description:Inhibition of liver delta-5 desaturase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116708(CHEMBL2263368)
Affinity DataIC50: 29nMAssay Description:Inhibition of D5D in human HepG2 cells using [14C]DGLA as substrate preincubated for 30 mins followed by substrate addition measured after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116703(CHEMBL3608696)
Affinity DataIC50: 34nMAssay Description:Inhibition of liver delta-5 desaturase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116768(CHEMBL3608702)
Affinity DataIC50: 50nMAssay Description:Inhibition of liver delta-5 desaturase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246007(CHEMBL4104260)
Affinity DataIC50: 55nMAssay Description:Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116773(CHEMBL3608795)
Affinity DataIC50: 58nMAssay Description:Inhibition of liver delta-5 desaturase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116708(CHEMBL2263368)
Affinity DataIC50: 58nMAssay Description:Inhibition of liver delta-5 desaturase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116772(CHEMBL3608794)
Affinity DataIC50: 59nMAssay Description:Inhibition of liver delta-5 desaturase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246065(CHEMBL4066595)
Affinity DataIC50: 60nMAssay Description:Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116704(CHEMBL3608695)
Affinity DataIC50: 67nMAssay Description:Inhibition of liver delta-5 desaturase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116771(CHEMBL3608793)
Affinity DataIC50: 84nMAssay Description:Inhibition of liver delta-5 desaturase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246046(CHEMBL4069465)
Affinity DataIC50: 150nMAssay Description:Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116781(CHEMBL2263369)
Affinity DataIC50: 155nMAssay Description:Inhibition of liver delta-5 desaturase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246006(CHEMBL4087912)
Affinity DataIC50: 170nMAssay Description:Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246022(CHEMBL4080025)
Affinity DataIC50: 170nMAssay Description:Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116770(CHEMBL3608704)
Affinity DataIC50: 173nMAssay Description:Inhibition of liver delta-5 desaturase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116705(CHEMBL460481)
Affinity DataIC50: 174nMAssay Description:Inhibition of liver delta-5 desaturase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246066(CHEMBL4085437)
Affinity DataIC50: 190nMAssay Description:Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116780(CHEMBL3608803)
Affinity DataIC50: 245nMAssay Description:Inhibition of liver delta-5 desaturase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116777(CHEMBL3608799)
Affinity DataIC50: 254nMAssay Description:Inhibition of liver delta-5 desaturase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116769(CHEMBL3608703)
Affinity DataIC50: 260nMAssay Description:Inhibition of liver delta-5 desaturase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116712(CHEMBL3608701)
Affinity DataIC50: 371nMAssay Description:Inhibition of liver delta-5 desaturase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116707(CHEMBL3608693)
Affinity DataIC50: 516nMAssay Description:Inhibition of liver delta-5 desaturase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116706(CHEMBL3608694)
Affinity DataIC50: 843nMAssay Description:Inhibition of liver delta-5 desaturase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116701(CHEMBL3608698)
Affinity DataIC50: 925nMAssay Description:Inhibition of liver delta-5 desaturase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246076(CHEMBL4063561)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50329966(2-(2'-fluorobiphenyl-4-yl)-6-(methylsulfonyl)-1H-b...)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of Delta(5) fatty acid desaturase in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50312701(5-methyl-3-(2-(4-(2-(trifluoromethyl)phenoxy)piper...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of delta5 desaturase in human HepG2 cells assessed as [14C]eicosatrienoic acid to [14C]arachidonic acid conversion pretreated 15 mins befo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
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