Compile Data Set for Download or QSAR
Report error Found 374 for UniProtKB: O55242
LigandPNGBDBM21025([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...)
Affinity DataIC50: 0.360nMAssay Description:Compound was tested for antagonistic activity against opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2018
Entry Details Article
PubMed
LigandPNGBDBM50369571(CHEMBL1790710)
Affinity DataIC50: 2.70nMAssay Description:Opioid receptor activity was evaluated using mouse vas deferens (MVD) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 2.80nMAssay Description:Compound was tested for agonistic activity against the opioid receptor in electrically stimulated mouse vas deference.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50225846(CHEMBL293145)
Affinity DataIC50: 7nMAssay Description:Compound was tested for agonist activity against opioid receptor in mouse vas deferens preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2018
Entry Details Article
PubMed
LigandPNGBDBM50002184(Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Ly...)
Affinity DataIC50: 7.80nMAssay Description:Opioid receptors antagonist activity in smooth-muscle tissue mouse vas deferens (MVD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50001465(2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataIC50: 8.40nMAssay Description:Concentration required to inhibit the specific binding of tritiated ligand [3H]DADL to opiate receptor by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details Article
PubMed
LigandPNGBDBM21025([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...)
Affinity DataIC50: 9nMAssay Description:Concentration required to inhibit the specific binding of tritiated ligand [3H]DADL to opiate receptor by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details Article
PubMed
LigandPNGBDBM50225254(CHEMBL610531)
Affinity DataIC50: 12.5nMAssay Description:In vitro binding affinity against opioid receptor using 1 nM [3H]- Naltrexone in the presence of 100 mM NaCl.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details Article
PubMed
LigandPNGBDBM50225849(CHEMBL301654)
Affinity DataIC50: 13nMAssay Description:Compound was tested for agonist activity against opioid receptor in mouse vas deferens preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2018
Entry Details Article
PubMed
LigandPNGBDBM50225254(CHEMBL610531)
Affinity DataIC50: 13nMAssay Description:In vitro binding affinity against opioid receptor using 1 nM [3H]- Naltrexone in the presence of 100 mM NaCl.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details Article
PubMed
LigandPNGBDBM50225254(CHEMBL610531)
Affinity DataIC50: 15nMAssay Description:In vitro binding affinity against opioid receptor using 1 nM of [3H]- Naltrexone in the absence of NaClMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details Article
PubMed
LigandPNGBDBM50225254(CHEMBL610531)
Affinity DataIC50: 15nMAssay Description:In vitro binding affinity against opioid receptor using 1 nM of [3H]- Naltrexone in the absence of NaClMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details Article
PubMed
LigandPNGBDBM50010703(CHEMBL443068 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Cys-A...)
Affinity DataIC50: 20nMAssay Description:Opioid receptors antagonist activity in smooth-muscle tissue mouse vas deferens (MVD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50010701(CHEMBL410616 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-D-Cys...)
Affinity DataIC50: 20nMAssay Description:Opioid receptors antagonist activity in smooth-muscle tissue mouse vas deferens (MVD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50225847(CHEMBL54820)
Affinity DataIC50: 21nMAssay Description:Compound was tested for agonist activity against opioid receptor in mouse vas deferens preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2018
Entry Details Article
PubMed
LigandPNGBDBM50010702(Dynorphin A (1-17) | dynorphin A | DYNORPHIN(1-17)...)
Affinity DataIC50: 23nMAssay Description:Opioid receptors antagonist activity in smooth-muscle tissue mouse vas deferens (MVD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50010706(CHEMBL384250 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-D-Cys...)
Affinity DataIC50: 25nMAssay Description:Opioid receptors antagonist activity in smooth-muscle tissue mouse vas deferens (MVD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50000092(Analog of 14-(Arylhydroxyamino)codeinone | 4-methy...)
Affinity DataIC50: 27nMAssay Description:Concentration required to inhibit [3H]naltrexone binding to Opioid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
LigandPNGBDBM50231235(CHEMBL441636)
Affinity DataIC50: 30nMAssay Description:Tested for displacement of radioligand [3H]-Naloxone from opiate receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50231227(CHEMBL328583)
Affinity DataIC50: 55nMAssay Description:Tested for displacement of radioligand [3H]-Naloxone from opiate receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50367061(NALORPHINE HYDROCHLORIDE | NALORPHINE)
Affinity DataIC50: 59nMAssay Description:Concentration required to inhibit the stereospecific [3H]diprenorphine binding Opioid receptors in the absence of sodium(Na+) was determined in mouse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
LigandPNGBDBM50225845(CHEMBL293967)
Affinity DataIC50: 70nMAssay Description:Compound was tested for agonist activity against opioid receptor in mouse vas deferens preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2018
Entry Details Article
PubMed
LigandPNGBDBM50001465(2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataIC50: 75nMAssay Description:Concentration required to inhibit the specific binding of tritiated ligand [3H]-naloxone to opiate receptor by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details Article
PubMed
LigandPNGBDBM50247803(Beta-Funeltrexamine | beta-funaltrexamine | methyl...)
Affinity DataIC50: 82nMAssay Description:Compound was tested for agonist activity against opioid receptor in mouse vas deferens preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2018
Entry Details Article
PubMed
LigandPNGBDBM50001674(CHEMBL344000 | 14-oxa-11,22-diazaheptacyclo[13.9.1...)
Affinity DataIC50: 85nMAssay Description:Compound was tested for agonistic activity against the opioid receptor in electrically stimulated mouse vas deferenceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50225255(CHEMBL2310924)
Affinity DataIC50: 115nMAssay Description:In vitro binding affinity against opioid receptor using 1 nM of [3H]- Naltrexone in the absence of NaClMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details Article
PubMed
LigandPNGBDBM50225255(CHEMBL2310924)
Affinity DataIC50: 115nMAssay Description:In vitro binding affinity against opioid receptor using 1 nM of [3H]- Naltrexone in the absence of NaClMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details Article
PubMed
LigandPNGBDBM50001675(CHEMBL285563 | 14-oxa-11,22-diazaheptacyclo[13.9.1...)
Affinity DataIC50: 124nMAssay Description:Compound was tested for agonistic activity against the opioid receptor in electrically stimulated mouse vas deferenceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50231230(CHEMBL328019)
Affinity DataIC50: 150nMAssay Description:Tested for displacement of radioligand [3H]-Naloxone from opiate receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50367061(NALORPHINE HYDROCHLORIDE | NALORPHINE)
Affinity DataIC50: 160nMAssay Description:Concentration required to inhibit the stereospecific [3H]diprenorphine binding Opioid receptors in the presence of sodium(Na+) was determined in mous...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
LigandPNGBDBM50001679(22-phenethyl-14-oxa-11,22-diazaheptacyclo[13.9.1.0...)
Affinity DataIC50: 171nMAssay Description:Compound was tested for agonistic activity against the opioid receptor in electrically stimulated mouse vas deferenceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50001677(22-phenethyl-14-oxa-11,22-diazaheptacyclo[13.9.1.0...)
Affinity DataIC50: 179nMAssay Description:Compound was tested for agonistic activity against the opioid receptor in electrically stimulated mouse vas deferenceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50231233(CHEMBL92960)
Affinity DataIC50: 200nMAssay Description:Tested for displacement of radioligand [3H]-Naloxone from opiate receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50010704(Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Ly...)
Affinity DataIC50: 204nMAssay Description:Opioid receptors antagonist activity in smooth-muscle tissue mouse vas deferens (MVD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50000092(Analog of 14-(Arylhydroxyamino)codeinone | 4-methy...)
Affinity DataIC50: 258nMAssay Description:Opioid receptor activity was evaluated using mouse vas deferens (MVD) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50231240(CHEMBL92779)
Affinity DataIC50: 400nMAssay Description:Tested for displacement of radioligand [3H]-Naloxone from opiate receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50010705(CHEMBL385759 | H-Tyr-Gly-Gly-Phe-Cys-Arg-Arg-Ile-A...)
Affinity DataIC50: 421nMAssay Description:Opioid receptors antagonist activity in smooth-muscle tissue mouse vas deferens (MVD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50026752(4-Ethoxycarbonyl-1-methyl-4-phenyl-piperidinium | ...)
Affinity DataIC50: 500nMAssay Description:Tested for displacement of radioligand [3H]-Naloxone from opiate receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50225255(CHEMBL2310924)
Affinity DataIC50: 880nMAssay Description:In vitro binding affinity against opioid receptor using 1 nM [3H]- Naltrexone in the presence of 100 mM NaCl.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details Article
PubMed
LigandPNGBDBM50225255(CHEMBL2310924)
Affinity DataIC50: 880nMAssay Description:In vitro binding affinity against opioid receptor using 1 nM [3H]- Naltrexone in the presence of 100 mM NaCl.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details Article
PubMed
LigandPNGBDBM50231231(CHEMBL92124)
Affinity DataIC50: 900nMAssay Description:Tested for displacement of radioligand [3H]-Naloxone from opiate receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50010700(CHEMBL265824 | H-Tyr-Gly-Gly-Phe-Cys-Arg-Arg-D-Ala...)
Affinity DataIC50: 1.66E+3nMAssay Description:Opioid receptors antagonist activity in smooth-muscle tissue mouse vas deferens (MVD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50003560(Levomethorpan | CHEMBL22207 | Dextromethorphan | 4...)
Affinity DataIC50: 2.00E+3nMAssay Description:Concentration required to inhibit [3H]naltrexone binding to Opioid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
LigandPNGBDBM50223879(CHEMBL280688)
Affinity DataIC50: 3.00E+3nMAssay Description:Concentration required to inhibit [3H]naltrexone binding to Opioid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
LigandPNGBDBM50017233(LEVO-DROMORAN | CHEMBL592 | LEVORPHANOL)
Affinity DataIC50: 4.00E+3nMAssay Description:Concentration required to inhibit [3H]naltrexone binding to Opioid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
LigandPNGBDBM50231236(CHEMBL89961)
Affinity DataIC50: 4.00E+3nMAssay Description:Tested for displacement of radioligand [3H]-Naloxone from opiate receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50231241(CHEMBL285244)
Affinity DataIC50: 5.00E+3nMAssay Description:Tested for displacement of radioligand [3H]-Naloxone from opiate receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50231237(CHEBI:6125 | Cetobemidone | Cliradon | Cymidon | K...)
Affinity DataIC50: 7.00E+3nMAssay Description:Tested for displacement of radioligand [3H]-Naloxone from opiate receptor; value ranges from 7-10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50231228(CHEMBL96626)
Affinity DataIC50: 8.00E+3nMAssay Description:Tested for displacement of radioligand [3H]-Naloxone from opiate receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50223880(CHEMBL610906)
Affinity DataIC50: 8.50E+3nMAssay Description:Concentration required to inhibit the stereospecific [3H]diprenorphine binding Opioid receptors in the absence of sodium(Na+) was determined in mouse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
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