Affinity DataEC50: 3.10nMT: 2°CAssay Description:Assay procedures: OCC culture solution was preheated in water tank at 37° C. Cells were taken out from liquor nitrogen tank, left on the dry-ice, and...More data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Affinity DataEC50: 133nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Affinity DataEC50: 82.6nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Affinity DataEC50: 8.90nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Affinity DataEC50: 0.600nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Affinity DataEC50: 1.20nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Affinity DataEC50: 49nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Affinity DataEC50: 38.6nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Affinity DataEC50: 19.2nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Affinity DataEC50: 4.40nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Affinity DataEC50: 21.4nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Affinity DataEC50: 5.70nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG...More data for this Ligand-Target Pair
Affinity DataEC50: 5.5nMAssay Description:Agonist activity against mouse S1P1 assessed as accumulation of cAMP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5.5nMAssay Description:Agonist activity against mouse S1P1 assessed as accumulation of cAMP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:Agonist activity at mouse S1P1 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production after 1 hr by HTRF a...More data for this Ligand-Target Pair
Affinity DataEC50: 77nMT: 2°CAssay Description:Assay procedures: OCC culture solution was preheated in water tank at 37° C. Cells were taken out from liquor nitrogen tank, left on the dry-ice, and...More data for this Ligand-Target Pair
Affinity DataEC50: 27nMT: 2°CAssay Description:Assay procedures: OCC culture solution was preheated in water tank at 37° C. Cells were taken out from liquor nitrogen tank, left on the dry-ice, and...More data for this Ligand-Target Pair
Affinity DataEC50: 8nMT: 2°CAssay Description:Assay procedures: OCC culture solution was preheated in water tank at 37° C. Cells were taken out from liquor nitrogen tank, left on the dry-ice, and...More data for this Ligand-Target Pair
Affinity DataEC50: 354nMT: 2°CAssay Description:Assay procedures: OCC culture solution was preheated in water tank at 37° C. Cells were taken out from liquor nitrogen tank, left on the dry-ice, and...More data for this Ligand-Target Pair
Affinity DataEC50: 20nMT: 2°CAssay Description:Assay procedures: OCC culture solution was preheated in water tank at 37° C. Cells were taken out from liquor nitrogen tank, left on the dry-ice, and...More data for this Ligand-Target Pair
Affinity DataEC50: 9.90nMT: 2°CAssay Description:Assay procedures: OCC culture solution was preheated in water tank at 37° C. Cells were taken out from liquor nitrogen tank, left on the dry-ice, and...More data for this Ligand-Target Pair
Affinity DataEC50: 14.3nMT: 2°CAssay Description:Assay procedures: OCC culture solution was preheated in water tank at 37° C. Cells were taken out from liquor nitrogen tank, left on the dry-ice, and...More data for this Ligand-Target Pair
Affinity DataEC50: 0.440nMAssay Description:Agonist activity at mouse S1P1 receptor assessed as cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0500nMAssay Description:Agonist activity at mouse S1P1 receptor assessed as cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0640nMAssay Description:Agonist activity at mouse S1P1 receptor assessed as cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0500nMAssay Description:Agonist activity at mouse S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8.30nMAssay Description:Agonist activity against mouse S1P1 assessed as accumulation of cAMP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40nMAssay Description:Agonist activity at mouse S1P1 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production after 1 hr by HTRF a...More data for this Ligand-Target Pair
Affinity DataEC50: 8.30nMAssay Description:Agonist activity against mouse S1P1 assessed as accumulation of cAMP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1×109 cells/pellet) were suspended in buffer containing 20 mM HEPES (4-(...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1×109 cells/pellet) were suspended in buffer containing 20 mM HEPES (4-(...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1×109 cells/pellet) were suspended in buffer containing 20 mM HEPES (4-(...More data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1×109 cells/pellet) were suspended in buffer containing 20 mM HEPES (4-(...More data for this Ligand-Target Pair
Affinity DataIC50: 48.7nMAssay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1×109 cells/pellet) were suspended in buffer containing 20 mM HEPES (4-(...More data for this Ligand-Target Pair
Affinity DataIC50: 69.4nMAssay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1×109 cells/pellet) were suspended in buffer containing 20 mM HEPES (4-(...More data for this Ligand-Target Pair
Affinity DataIC50: 119nMAssay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1×109 cells/pellet) were suspended in buffer containing 20 mM HEPES (4-(...More data for this Ligand-Target Pair
Affinity DataIC50: 151nMAssay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1×109 cells/pellet) were suspended in buffer containing 20 mM HEPES (4-(...More data for this Ligand-Target Pair
Affinity DataIC50: 183nMAssay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1×109 cells/pellet) were suspended in buffer containing 20 mM HEPES (4-(...More data for this Ligand-Target Pair
