Compile Data Set for Download or QSAR
Report error Found 1205 for UniProtKB: O00255
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50366388(NEOMYCIN A | NEOMYCIN)
Affinity DataKd:  1.56E+4nMAssay Description:Binding affinity to menin (unknown origin) by isothermal titration calorimetry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50156121(CHEMBL3780497)
Affinity DataKd:  24nMAssay Description:Binding affinity to menin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50156122(CHEMBL3781030)
Affinity DataKd:  6.5nMAssay Description:Binding affinity to menin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50455873(CHEMBL4216801)
Affinity DataKd:  9nMAssay Description:Binding affinity to human C-terminal Avi-tagged menin expressed in Escherichia coli BL21 (DE3) cells by bio-layer interferometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50455876(CHEMBL4217916)
Affinity DataKd:  24nMAssay Description:Binding affinity to human C-terminal Avi-tagged menin expressed in Escherichia coli BL21 (DE3) cells by bio-layer interferometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM152235(US8993552, 70)
Affinity DataKd:  158nMAssay Description:Binding affinity to menin (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50454122(CHEMBL4206413)
Affinity DataKd:  22nMAssay Description:Binding affinity to menin (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50454124(CHEMBL3780822)
Affinity DataKd:  9.30nMAssay Description:Binding affinity to menin (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50496327(CHEMBL3126198)
Affinity DataKd:  85nMAssay Description:Binding affinity to human menin by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50496328(CHEMBL3126187)
Affinity DataKd:  285nMAssay Description:Binding affinity to human menin by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50496340(CHEMBL3124953)
Affinity DataKd:  952nMAssay Description:Binding affinity to human menin by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50489222(CHEMBL2314822)
Affinity DataKd:  1.40nMAssay Description:Binding affinity to menin (unknown origin) after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50489223(CHEMBL2314821)
Affinity DataKd:  16nMAssay Description:Binding affinity to menin (unknown origin) after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50454124(CHEMBL3780822)
Affinity DataKd:  10nMAssay Description:Binding affinity to human Menin expressed in Escherichia coli Rosetta2 (DE3) cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50156122(CHEMBL3781030)
Affinity DataKd:  10nMAssay Description:Binding affinity to human Menin expressed in Escherichia coli Rosetta2 (DE3) cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50455873(CHEMBL4216801)
Affinity DataKd:  10nMAssay Description:Binding affinity to human Menin expressed in Escherichia coli Rosetta2 (DE3) cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50496346(CHEMBL3126196)
Affinity DataKd:  1.10E+5nMAssay Description:Binding affinity to biotinylated Menin (unknown origin) by biolayer interferometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50516582(CHEMBL4449381)
Affinity DataKd:  1.40E+3nMAssay Description:Binding affinity to biotinylated Menin (unknown origin) by biolayer interferometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50455859(CHEMBL3780895)
Affinity DataKd:  10nMAssay Description:Binding affinity to human Menin expressed in Escherichia coli Rosetta2 (DE3) cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50540837(CHEMBL4647785)
Affinity DataKd:  82nMAssay Description:Binding affinity to human Menin expressed in Escherichia coli BL21 (DE3) assessed as inhibition of Menin/MLL1 protein-protein at 20 degree C by isoth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM689587(US20240261292, Compound A | US20240261292, Compoun...)
Affinity DataIC50: 0.0900nMAssay Description:To an untreated, white 384-well microtiter plate was added 40 nL 200�� test compound in DMSO and 4 uL 2�� terbium chelate-labeled menin (vide infra f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2024
Entry Details
Go to US Patent

TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM689589(US20240261292, Compound A3 | oxalate )
Affinity DataIC50: 0.0980nMAssay Description:To an untreated, white 384-well microtiter plate was added 40 nL 200�� test compound in DMSO and 4 uL 2�� terbium chelate-labeled menin (vide infra f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2024
Entry Details
Go to US Patent

TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM689587(US20240261292, Compound A | US20240261292, Compoun...)
Affinity DataIC50: 0.110nMAssay Description:To an untreated, white 384-well microtiter plate was added 40 nL 200�� test compound in DMSO and 4 uL 2�� terbium chelate-labeled menin (vide infra f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2024
Entry Details
Go to US Patent

TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM689590(US20240261292, Compound A1)
Affinity DataIC50: 0.180nMAssay Description:To an untreated, white 384-well microtiter plate was added 40 nL 200�� test compound in DMSO and 4 uL 2�� terbium chelate-labeled menin (vide infra f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2024
Entry Details
Go to US Patent

TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50454121(CHEMBL4211366)
Affinity DataIC50: 1nMAssay Description:Displacement of FITC-MBM1 from menin (unknown origin) measured after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50511905(CHEMBL4530300)
Affinity DataIC50: 1nMAssay Description:Inhibition of fluorescent labeled tracer binding to Menin (unknown origin) after 1 hr by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM506357(methyl ((1S,2R)-2-((S)-1-(1-((1-(4-((1-((E)-4- (di...)
Affinity DataIC50: 1nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
Go to US Patent

TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50511899(CHEMBL4457657 | US11045448, Cpd. No. 67)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of fluorescent labeled tracer binding to Menin (unknown origin) after 1 hr by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50582737(CHEMBL5076146)
Affinity DataIC50: 1.70nMAssay Description:Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50511898(CHEMBL4456868)
Affinity DataIC50: 2nMAssay Description:Inhibition of fluorescent labeled tracer binding to Menin (unknown origin) after 1 hr by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50511900(CHEMBL4454017 | US11045448, Cpd. No. 72)
Affinity DataIC50: 2nMAssay Description:Inhibition of fluorescent labeled tracer binding to Menin (unknown origin) after 1 hr by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50511901(CHEMBL4528467)
Affinity DataIC50: 2nMAssay Description:Inhibition of fluorescent labeled tracer binding to Menin (unknown origin) after 1 hr by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50511902(CHEMBL4553102)
Affinity DataIC50: 2nMAssay Description:Inhibition of fluorescent labeled tracer binding to Menin (unknown origin) after 1 hr by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50511903(CHEMBL4588924)
Affinity DataIC50: 2nMAssay Description:Inhibition of fluorescent labeled tracer binding to Menin (unknown origin) after 1 hr by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50511908(CHEMBL4456003)
Affinity DataIC50: 2nMAssay Description:Inhibition of fluorescent labeled tracer binding to Menin (unknown origin) after 1 hr by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50511910(CHEMBL4450979)
Affinity DataIC50: 2nMAssay Description:Inhibition of fluorescent labeled tracer binding to Menin (unknown origin) after 1 hr by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50511912(CHEMBL4571451)
Affinity DataIC50: 2nMAssay Description:Inhibition of fluorescent labeled tracer binding to Menin (unknown origin) after 1 hr by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM506337(methyl ((1S,2R)-2-((S)-(1-((1-(4-((3- acrylamidoph...)
Affinity DataIC50: 2nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
Go to US Patent

TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM506340(methyl ((1S,2R)-2-((S)-1-(1-((1-(4-((1-acryloylaze...)
Affinity DataIC50: 2nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
Go to US Patent

TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM506341(methyl ((1S,2R)-2-((S)-1-(1-((1-(4-((3- acrylamido...)
Affinity DataIC50: 2nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
Go to US Patent

TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM506342((1S,2R)-2-((S)-(1-((1-(4-((4- acrylamidophenyl)sul...)
Affinity DataIC50: 2nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
Go to US Patent

TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM506346(methyl ((1S,2R)-2-((S)-1-(1-((1-(4-((1-acryloylaze...)
Affinity DataIC50: 2nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
Go to US Patent

TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM506354(methyl ((1S,2R)-2-((S)-cyano(1-((1-(4-((3-((E)-4- ...)
Affinity DataIC50: 2nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
Go to US Patent

TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50511899(CHEMBL4457657 | US11045448, Cpd. No. 67)
Affinity DataIC50: 2nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
Go to US Patent

TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50511900(CHEMBL4454017 | US11045448, Cpd. No. 72)
Affinity DataIC50: 2nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
Go to US Patent

TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM506364(methyl ((1S,2R)-2-((S)-2-(2-ethyl-1H-imidazol-1-yl...)
Affinity DataIC50: 2nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
Go to US Patent

TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50582744(CHEMBL5085940)
Affinity DataIC50: 2.5nMAssay Description:Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50511904(CHEMBL4438797)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of fluorescent labeled tracer binding to Menin (unknown origin) after 1 hr by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50582746(CHEMBL5081367)
Affinity DataIC50: 2.70nMAssay Description:Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetMenin(Human)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50582751(CHEMBL5094183)
Affinity DataIC50: 2.70nMAssay Description:Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
Displayed 1 to 50 (of 1205 total ) | Next | Last >>
Jump to: