Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) for PDB: 9VJG
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016777BDBM50016777(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)
Affinity DataKi:  0.100nMAssay Description:Binding affinity at 5-hydroxytryptamine 1A receptor in bovine hippocampal preparation using [3H]8-OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1A(Mouse)
University of G£Teborg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016777BDBM50016777(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)
Affinity DataKi:  0.5nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016777BDBM50016777(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016777BDBM50016777(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity was measured on cloned Human 5-hydroxytryptamine 1A receptor which is labeled by [3H]8-OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016777BDBM50016777(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016777BDBM50016777(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of [3H]- 8-OH-DPAT binding to 5-HT1A-receptor from rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article
PDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016777BDBM50016777(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)
Affinity DataKi:  3.10nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT (agonist) as radioligand (sc)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016777BDBM50016777(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)
Affinity DataKi:  4.10nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor in rat brain tissue using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016777BDBM50016777(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)
Affinity DataIC50: 4.80nMAssay Description:Concentration of compound required to inhibit cortical 5-hydroxytryptamine 1A receptor binding sites in rat brain was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016777BDBM50016777(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)
Affinity DataKi:  4.80nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley rat cortex membranes after 15 mins by liquid scintillation spectrometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1A(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016777BDBM50016777(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)
Affinity DataKi:  7.10nMAssay Description:Displacement of [3H]-5-carboxamidotryptamine from human 5-HT1A receptor expressed in HEK293T cell membranes incubated for 90 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)