Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) for PDB: 9UGL
Target5-hydroxytryptamine receptor 2C(Rat)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85097BDBM85097(CAS_181632-25-7 | CHEMBL14563 | SB 242084)
Affinity DataKi:  0.160nMAssay Description:Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2C(Human)
Dominican College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85097BDBM85097(CAS_181632-25-7 | CHEMBL14563 | SB 242084)
Affinity DataIC50: 0.330nMAssay Description:Antagonist activity at recombinant human 5-HT2C expressed in human U2OS cells by pathhunter beta-arrestin assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2C(Human)
Dominican College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85097BDBM85097(CAS_181632-25-7 | CHEMBL14563 | SB 242084)
Affinity DataKi:  0.480nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2C(Human)
Dominican College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85097BDBM85097(CAS_181632-25-7 | CHEMBL14563 | SB 242084)
Affinity DataKi:  1nMAssay Description:Binding affinity towards human cloned 5-hydroxytryptamine receptor 2C in HEK293 cells, using [3H]mesulergine as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2C(Human)
Dominican College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85097BDBM85097(CAS_181632-25-7 | CHEMBL14563 | SB 242084)
In Depth
Date in BDB:
2/26/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2C(Human)
Dominican College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85097BDBM85097(CAS_181632-25-7 | CHEMBL14563 | SB 242084)
Affinity DataKi:  1nMAssay Description:Binding affinity for human 5-hydroxytryptamine 2C receptor expressed in HEK 293 cells using [3H]mesulergineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2C(Human)
Dominican College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85097BDBM85097(CAS_181632-25-7 | CHEMBL14563 | SB 242084)
Affinity DataKi:  1nMAssay Description:Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2C(Human)
Dominican College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85097BDBM85097(CAS_181632-25-7 | CHEMBL14563 | SB 242084)
Affinity DataKi:  7.08nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)