Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 9M4T
TargetAlpha-1A adrenergic receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160154BDBM50160154(CHEMBL24778 | 1-(3-Hydroxy-propyl)-5-((R)-2-{2-[2-...)
Affinity DataKi:  0.0360nMAssay Description:Binding constant measured against Alpha-1A adrenergic receptor in human prostate; +++:highly activeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAlpha-1A adrenergic receptor(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160154BDBM50160154(CHEMBL24778 | 1-(3-Hydroxy-propyl)-5-((R)-2-{2-[2-...)
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at alpha1A adrenoceptor in Sprague-Dawley rat urethra assessed as inhibition of norepinephrine-induced smooth muscle contraction ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAlpha-1A adrenergic receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160154BDBM50160154(CHEMBL24778 | 1-(3-Hydroxy-propyl)-5-((R)-2-{2-[2-...)
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at human full-length N-terminal SNAP-tagged alpha1A adrenoceptor expressed in HEK293 cells assessed as inhibition of agonist-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAlpha-1A adrenergic receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160154BDBM50160154(CHEMBL24778 | 1-(3-Hydroxy-propyl)-5-((R)-2-{2-[2-...)
Affinity DataIC50: 1.90nMAssay Description:Antagonist activity at human alpha-1A adrenergic receptor transfected in HEK293 cells assessed as reduction in agonist-induced calcium mobilization a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)