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Found
1
Enz. Inhib. hit(s) for PDB:
9GNO
Target
Cyclin-dependent kinase 2/G1/S-specific cyclin-D1
(Human)
AstraZeneca
US Patent
Ligand
BDBM752844
(US20250197425, Example 20)
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Affinity Data
IC50: 13nM
Assay Description:
Compounds were tested in breast cancer cell line MCF-7 to assess inhibition of CDK1, CDK2, and CDK4 activity. MCF-7 cells transiently transfected wit...
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Target Info
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Ligand Info
PC cid
PC sid
PDB
In Depth
Date in BDB:
10/15/2025
Entry Details
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US Patent
PDB
3D Structure (crystal)
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