| Assay Method Information | |
| | ChEMBL_1436389 (CHEMBL3389592) |
| Description: | Inhibition of N-terminal His6-tagged mouse DNMT1 (731 to 1602 residues) expressed in Escherichia coli BL21 (DE3) incubated for 15 mins before addition of [3H]-SAM and poly(dI-dC).poly(dI-dC) by liquid scintillation counting based radioactive methylation assay |
| Affinity data for this assay | |
|---|---|
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