| Assay Method Information | |
| | ChEMBL_1688692 (CHEMBL4039262) |
| Description: | Negative allosteric modulation of rat mGlu5 receptor expressed in HEK293A cells assessed as inhibition of glutamate induced-calcium mobilization preincubated for 2.3 mins followed by glutamate addition measured after 2.6 mins in presence of 5-Methyl-6-(phenylethynyl)-pyridine by Fluo-4 AM dye based fluorescence assay |
| Affinity data for this assay | |
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