| Assay Method Information | |
| | ChEMBL_2024835 (CHEMBL4678648) |
| Description: | Inhibition of ABCB1 in multidrug-resistant human SW620/Ad300 cells assessed as increase in reversal of resistance to paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 20 uM pre-incubated for 4 hrs followed by paclitaxel addition and measured after 72 hrs by MTT assay (Rvb = 4233.18 +/- 499.10 nM) |
| Affinity data for this assay | |
|---|---|
| If you find an error in this entry please send us an E-mail | |