| Assay Method Information | |
| | ChEMBL_2363307 |
| Description: | Inhibition of NLRP3 inflammasome activation in LPS-induced human THP-1 cells expressing GFP-tagged ASC assessed as disruption of ASC speck formation pretreated for 2 hrs with LPS followed by compound addition for 30 mins and further incubated with zVAD-FMK and nigericin for 1 hr by Hoechst 33342 staining based analysis |
| Affinity data for this assay | |
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