Assay Method Information | |
| ChEMBL_1785274 (CHEMBL4256791) |
Description: | Inhibition of human WDR5 (22 to 334 residues) assessed as reduction in WRAD-mediated human MLL1 ( 3745 to 3969 residues) H3K4 methylation using human HeLa cells oligonucleosomes as substrate and 3H-SAM as methylation cofactor by radioisotope-based filter-binding assay |
Affinity data for this assay | |
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