| Assay Method Information | |
| | ChEMBL_2330622 |
| Description: | Negative allosteric modulator activity at human P-gp T1226Y mutant expressed in HEK293FT cells assessed as reversal of P-gp mediated PTX resistance by measuring paclitaxel IC50 incubated for 5 days by MTS assay (Rvb = 449.3 +/- 31.2 nM) |
| Affinity data for this assay | |
|---|---|
| If you find an error in this entry please send us an E-mail | |